56 research outputs found

    Magnetorheological Elastomers: Materials and Applications

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    Magnetorheological elastomers (MREs) are a type of soft magneto-active rubber-like material, whose physical or mechanical properties can be altered upon the application of a magnetic field. In general, MREs can be prepared by mixing micron-sized magnetic particles into nonmagnetic rubber-like matrices. In this chapter, the materials, the preparing methods, the analytical models, and the applications of MREs are reviewed. First, different kinds of magnetic particles and rubber-like matrices used to prepare MREs, as well as the preparing methods, will be introduced. Second, some examples of the microstructures, as well as the microstructure-based analytical models, of MREs will be shown. Moreover, the magnetic field-induced changes of the macroscopic physical or mechanical properties of MREs will be experimentally given. Third, the applications of MREs in engineering fields will be introduced and the promising applications of MREs will be forecasted. This chapter aims to bring the reader a first-meeting introduction for quickly knowing about MREs, instead of a very deep understanding of MREs

    Magneto-Sensitive Smart Materials and Magnetorheological Mechanism

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    Magneto-sensitive smart materials, also named as magnetorheological (MR) materials, are a class of smart composites prepared by dispersing nanometer- or micrometer-sized ferromagnetic fillers into the different carrier matrix. As the rheological properties can be controlled by an external magnetic field rapidly, reversibly, and continuously, magneto-sensitive smart materials have great application potential in construction, automotive industry, artificial intelligence, etc. In this chapter, a brief history and classification of magneto-sensitive smart materials are firstly summarized. Next, we discuss the state-of-the-art of the magnetorheological mechanism through experimental and theoretical studies, respectively. Finally, the prospect for this material in the future is presented

    Screening and Degradation Characteristics of a Fumonisin B1-Degrading Fungal Strain

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    A fungal strain capable of degrading fumonisin B1 (FB1) from ground maize samples heavily contaminated with fumonisin was obtained by enrichment culture method. The strain was named as FDS-2, and was characterized for its growth and degradation characteristics, and the initial degradation pathway of FB1 by FDS-2 was investigated. The strain was identified as Exophiala spinifera according to its culture characteristics, microscopic characteristics and phylogenetic tree based on RNA-internal transcribed spacer (ITS) sequence characteristics. The optimum growth and degradation conditions were 30 ℃ and pH 5.0. Under these conditions, the strain could completely degrade 250 μg of FB1 within 48 h. Intracellular FB1-degrading enzymes were discovered in this strain. Using liquid chromatography-mass spectrometry (LC-MS) to analyze the degradation products, it was determined that the primary degradation pathway began with the degradation of FB1 into hydrolyzed FB1. This study provides a strain resource and a theoretical basis for the biodegradation of fumonisin in grain and feed

    PRMT5 is upregulated by B-cell receptor signaling and forms a positive-feedback loop with PI3K/AKT in lymphoma cells

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    PRMT5, which regulates gene expression by symmetric dimethylation of histones and non-histone target proteins, is overexpressed and plays a pathogenic role in many cancers. In diffuse large B cell lymphoma (DLBCL), the mechanisms of PRMT5 dysregulation and its role in lymphomagenesis remain largely unknown. Here we demonstrate that B cell receptor (BCR) signaling regulates PRMT5 expression in DLBCL cells. Immunohistochemical analysis reveals elevated levels of PRMT5 expression in DLBCL cases and in germinal center (GC) B cells when compared to naive B cells. PRMT5 can be induced in naive B cells by BCR stimulation. We discovered that BTK-NF-κB signaling induces PRMT5 transcription in activated B cell-like (ABC) DLBCL cells while BCR downstream PI3K-AKT-MYC signaling upregulates PRMT5 expression in both ABC and GCB DLBCL cells. PRMT5 inhibition inhibits the growth of DLBCL cells in vitro and patient derived xenografts. Genomic and biochemical analysis demonstrate that PRMT5 promotes cell cycle progression and activates PI3K-AKT signaling, suggesting a feedback regulatory mechanism to enhance cell survival and proliferation. Co-targeting PRMT5 and AKT by their specific inhibitors is lethal to DLBCL cell lines and primary cancer cells. Therefore, this study provides a mechanistic rationale for clinical trials to evaluate PRMT5 and AKT inhibitors for DLBCL

    A Virtual Point-Oriented Control for Distance-Based Directed Formation and Its Application to Small Fixed-Wing UAVs

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    This paper proposes a new algorithm to solve the control problem for a special class of distance-based directed formations, namely directed-triangulated Laman graphs. The central idea of the algorithm is to construct a virtual point for the agents who have more than two neighbors by employing the information of the desired formation. Compared with the existing methods, the proposed algorithm can make the distance error between the agents converge faster and the path consumption is less. Furthermore, the proposed algorithm is modified to be operable for the small fixed-wing UAV model with nonholonomic and input constraints. Finally, the effectiveness of the proposed method is verified by a series of simulation experiments

    STUDY ON THE MICROMECHANICAL MODEL OF FORCE-MAGNETIC COUPLING FOR FERROGEL MATERIALS

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    The ferrogel sample was prepared by carbonyl iron powder as conductive phase and vulcanized silicone rubber as matrix. The microstructure and mechanical properties of the sample are analyzed and tested by using X ray diffractometer( XRD)and MTS testing machine. Based on the analysis of the microstructure and morphology features and the compression performance data,a stress-magnetization coupled model was established in accordance with the magnetic interaction between particles,and some factors influencing on magneto-induced effect and macroscopic response of ferrogel are analyzed theoretically,including the magnetic particle content,size ratio,magnetic field strength and compress strain etc. The results show that the roughness has little effect on the average peak shear stress when compress strain is low,while with the increase of the normal stress,the magneto-induced effect comes into play. And the magneto-induced compressive modulus of ferrogel tends to increase with the increment of the magnetic particle content,size ratio,magnetic field strength and compression strain. If the mass fraction of the magnetic granular in ferrogel is more than 70wt%,the ductility and fracture toughness of ferrogel composites would be notably reduced. In order to gain ferrogel composites with excellent magneto-induced effect,the the optimized combination of the selected factors would be employed were in the preparation of ferrogel materials. This provides theoretical help for material production and optimization of functions and behaviors for the device

    Recent progress on the magnetorheological plastomers

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    Different from the traditional magnetorheological (MR) fluids and elastomers, the magnetic particles in the plastic MR materials are not ‘deadly’ trapped in the polymer matrix; thus, the MR plastomers exhibit higher MR effects and lower sedimentation. The plastic MR materials have attracted increasing attention, and the relevant fundamental mechanisms and practical applications have been intensively studied due to their unique physical and mechanical properties. In this highlight, we have mainly reviewed the preparation and the rheological properties of the MR plastomers. The formation mechanism of the MR plastomers has also been briefly summarized

    A Virtual Point-Oriented Control for Distance-Based Directed Formation and Its Application to Small Fixed-Wing UAVs

    No full text
    This paper proposes a new algorithm to solve the control problem for a special class of distance-based directed formations, namely directed-triangulated Laman graphs. The central idea of the algorithm is to construct a virtual point for the agents who have more than two neighbors by employing the information of the desired formation. Compared with the existing methods, the proposed algorithm can make the distance error between the agents converge faster and the path consumption is less. Furthermore, the proposed algorithm is modified to be operable for the small fixed-wing UAV model with nonholonomic and input constraints. Finally, the effectiveness of the proposed method is verified by a series of simulation experiments

    Effect of B4Cp content on microstructure and the high-temperature oxidation behavior of Ti-5.4Al-4.03Mo-3.93V-2.37Cr-0.01Zr composites

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    The paper discusses the effects of B _4 C particle (B _4 C _p ) content on the microstructure and high-temperature oxidation resistance of B _4 C _p /Ti-5.4Al-4.03Mo-3.93V-2.37Cr-0.01Zr composite prepared by powder metallurgy. The results demonstrate that grain size of the composites decreases by increasing reinforcement content from 1 to 3 wt.%, suggesting that B _4 C _p can refine grain of the materials. For the composites with increasing B _4 C _p content from 0 to 3 wt.%, the apparent porosity increase from 3.23 to 6.89%, indicating that the density of materials decreased with the increase of B _4 C _P content. In addition, the hardness of the materials have been greatly improved. Comparing to the substrate 434.02 HV, the 1, 2, and 3 wt.% B _4 C _P specimens are increased by 37.2%, 57.5%, and 84.7%, respectively. The weight of the oxidation product is reduced and the oxidation rate is slowed down, as the B _4 C _P content increases. Moreover, the thickness of the oxide layer is greatly reduced, and the thickness of oxidation layer in composites with 0, 1, 2 and 3 wt.% B4CP specimens were 60, 55, 47 and 40 μ m, indicating that B _4 C _P can improve the high-temperature oxidation resistance
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