In vitro and ex vivo measurement of the biophysical properties of blood using microfluidic platforms and animal models

Haemorheologically impaired microcirculation, such as blood clotting or abnormal blood flow, causes interrupted blood flows in vascular networks. The biophysical properties of blood, including blood viscosity, blood viscoelasticity, haematocrit, red blood bell (RBC) aggregation, erythrocyte sedimentation rate and RBC deformability, have been used to monitor haematological diseases. In this review, we summarise several techniques for measuring haemorheological properties, such as blood viscosity, RBC deformability and RBC aggregation, using in vitro microfluidic platforms. Several methodologies for the measurement of haemorheological properties with the assistance of an extracorporeal rat bypass loop are also presented. We briefly discuss several emerging technologies for continuous, long-term, multiple measurements of haemorheological properties under in vitro or ex vivo conditions.11Ysciescopu

tert-Butyl 4-formyl-1H-imidazole-1-carboxyl­ate

In the crystal structure of the title compound, C9H12N2O3, weak inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into chains. Further weak C—H⋯O hydrogen bonds together with π–π inter­actions [centroid–centroid distance = 3.672 (4) Å] between neighbouring chains lead to a double-chain structure propagating in [100]

Structural and spectral dynamics of single-crystalline Ruddlesden-Popper phase halide perovskite blue light-emitting diodes.

Achieving perovskite-based high-color purity blue-emitting light-emitting diodes (LEDs) is still challenging. Here, we report successful synthesis of a series of blue-emissive two-dimensional Ruddlesden-Popper phase single crystals and their high-color purity blue-emitting LED demonstrations. Although this approach successfully achieves a series of bandgap emissions based on the different layer thicknesses, it still suffers from a conventional temperature-induced device degradation mechanism during high-voltage operations. To understand the underlying mechanism, we further elucidate temperature-induced device degradation by investigating the crystal structural and spectral evolution dynamics via in situ temperature-dependent single-crystal x-ray diffraction, photoluminescence (PL) characterization, and density functional theory calculation. The PL peak becomes asymmetrically broadened with a marked intensity decay, as temperature increases owing to [PbBr6]4- octahedra tilting and the organic chain disordering, which results in bandgap decrease. This study indicates that careful heat management under LED operation is a key factor to maintain the sharp and intense emission

TESTING OF ROTATIONAL EXERCISE EQUIPMENT TO IMPROVE THE VESTIBULAR SYSTEM

The primary purpose of this study was to test the effect of training using the rotational exercise equipment developed in this study on the improvement of the vestibular system. In order to test the rotational exercise equipment developed in this study, 15 ordinary college students had trainings for 8 weeks and their nystagmus intensity was analyzed. The findings showed that the rotational training using the rotational exercise equipment affected vestibular balance, as it significantly decreased the slow phase velocity (SPV) immediately after rotational stimulation and reduced the recovery time of nystagmus to normal