In vitro specific interactions revealed the infective characteristics of fungal endophytes to grapevine

In the present study a method for co-culture of fungal endophytic strains and grape cells was developed in order to study their interactions, and filter candidates for further safe inoculation in the vineyard. Analysis of morphological and physiological traits was performed by measuring the plant callus and fungal growth, plant cells viability, degree of cell oxidation and the scale of contact or its absence as reaction of the fungal endophyte to the presence of the plant callus. Accordingly, endophytic fungal strains (EFS) were classified on scale of invasion into categories (strong - medium - weak invasive), as well as the contact between the two partners (grow into - grow onto - contact - no contact) and the grape cell oxidation degree (normal (no oxidation) - light - moderate - serious). More included the dominance and distribution of EFS in the plant host, and correlation plots of physiological traits during plant callus and endophytic fungi co–culture were calculated

Almost Sure Stability and Stabilization for Hybrid Stochastic Systems with Time-Varying Delays

The problems of almost sure (a.s.) stability and a.s. stabilization are investigated for hybrid stochastic systems (HSSs) with time-varying delays. The different time-varying delays in the drift part and in the diffusion part are considered. Based on nonnegative semimartingale convergence theorem, Hölder’s inequality, Doob’s martingale inequality, and Chebyshev’s inequality, some sufficient conditions are proposed to guarantee that the underlying nonlinear hybrid stochastic delay systems (HSDSs) are almost surely (a.s.) stable. With these conditions, a.s. stabilization problem for a class of nonlinear HSDSs is addressed through designing linear state feedback controllers, which are obtained in terms of the solutions to a set of linear matrix inequalities (LMIs). Two numerical simulation examples are given to show the usefulness of the results derived

The Dual-mediation Effect of Perceived Accuracy and Perceived Connectedness on Consumer Attitude Toward Social Network Advertising

Drawing on the stimulus-organism-response (S-O-R) model, this paper investigates the dual mediation effect of perceived accuracy and perceived connectedness in the effect of endorsement from satisfied customers, review credibility, and social influence on consumers’ social media advertising attitudes. A study was conducted and received 1597 returned surveys with 1031 valid surveys. The results show that endorsement from satisfied customers, review credibility, and social influence are antecedents of perceived accuracy and perceived connectedness. These five variables are also antecedents of consumer attitude toward social network advertising. Furthermore, perceived accuracy and connectedness are partially mediating these relationships between endorsement from satisfied customers/review credibility/social influence and consumer attitude toward social network advertising

Chloridotetra­kis(pyridine-4-carb­alde­hyde-κN)copper(II) chloride

In the mol­ecular structure of the title compound, [CuCl(C6H5NO)4]Cl, the CuII atom is coordinated by four N atoms of four pyridine-4-carboxaldehyde ligands and one chloride anion in a slightly distorted square-pyramidal coordination geometry. There is also a non-coordinating Cl− anion in the crystal structure. The CuII atom and both Cl atoms are situated on fourfold rotation axes. A weak C—H⋯Cl inter­action is also present

{N′-[(E)-(5-Bromo-2-oxidophen­yl)(phen­yl)methyl­ene]benzohydrazidato}pyridine­copper(II)

The asymmetric unit of title complex, [Cu(C20H13BrN2O2)(C5H5N)], contains two independent mol­ecules. In each mol­ecule, the central CuII atom has a square-planar environment formed by the tridentate hydrazone and the monodentate pyridine ligands, with the N atoms in a trans arrangement about the CuII atom

Host structural stabilization of Li1.232Mn0.615Ni0.154O2 through K-doping attempt: toward superior electrochemical performances

Lithium-rich layered cathodes are known famously for its superior capacity over traditional layered oxides but trapped for lower initial coulombic efficiency, poorer rate capability and worse cyclic stability in spite of diverse attempts. Herein, a new K-stabilized Li-rich layered cathode synthesized through a simple oxalate co-precipitation is reported for its super electrochemical performances. Compared with pristine Li-rich layered cathode, K-stabilized one reaches a higher initial coulombic efficiency of 87% from 76% and outruns for 94% of capacity retention and 244 mAh g-1 of discharge capacity at 0.5C after 100 cycles. Moreover, 133 mAh g-1 of discharge capacity can be delivered even charged at 10C showing a highly-improved rate capability. X-ray diffraction and electrochemical impedance spectroscopy tests show that enlarged Li slab layer caused by K+ accommodation can provide facile Li+ diffusion paths and facilitate Li+ migration from the crystal lattice. As a consequence, the introduction of K+ in the host layered structure can inhibit the detrimental spinel structure growth during cycling. Therefore, the K-stabilized Li-rich layered materials can be considered to be an attractive alternative to meet with the higher power and energy density demands of advanced lithium-ion battery

The expression of PLK-1 in cervical carcinoma: a possible target for enhancing chemosensitivity

<p>Abstract</p> <p>Background</p> <p>Polo-like kinase-1 (PLK-1) is reported to be upregulated in a variety of human tumors and is implicated in cell proliferation and survival. However, its importance in cervical carcinoma has not yet been fully elucidated.</p> <p>Methods</p> <p>We examined PLK-1 expression in cervical carcinoma tissues using immunohistochemical staining. Furthermore, we blocked PLK-1 expression in HeLa cells using specific siRNA and detected the cell cycle, cell proliferation and chemosensitivity using western blotting, MTT and flow cytometry.</p> <p>Results</p> <p>We provide evidence that expression of PLK-1 exists in human cervical carcinoma tissues and establish an association with tumor size. Furthermore, we show that PLK-1 knockdown by transfection of siRNA induces accumulation of HeLa cells in the G2/M cell cycle phase and enhances cisplatin-induced apoptosis.</p> <p>Conclusion</p> <p>Our results indicate that PLK-1 production in HeLa cells might be critical in determining whether cells survive or undergo apoptosis. Therefore, targeting PLK-1 might be a promising strategy for enhancing sensitivity to chemotherapeutic reagents in cervical carcinoma.</p

Clinical significance of the advanced lung cancer inflammation index in gastrointestinal cancer patients: a systematic review and meta-analysis

BackgroundThe advanced lung cancer inflammation index (ALI) has been identified as a scientific and clinical priority in multiple malignancies. The aim of this study is to investigate the value of the ALI before treatment in evaluating postoperative complications (POCs) and survival outcomes in patients with gastrointestinal (GI) cancer.MethodsElectronic databases including PubMed, Embase and Web of Science were comprehensively reviewed up to June 2022. The endpoints were POCs and survival outcomes. Subgroup analyses and sensitivity analyses were also performed.ResultsEleven studies including 4417 participants were included. A significant heterogeneity in the ALI cut-off value among studies was observed. Patients in the low ALI group showed increased incidence of POCs (OR=2.02; 95%CI:1.60-2.57; P&lt;0.001; I2 = 0%). In addition, a low ALI was also significantly associated with worse overall survival (HR=1.96; 95%CI: 1.58-2.43; P&lt;0.001; I2 = 64%), which remained consistent in all subgroups based on country, sample size, tumor site, tumor stage, selection method and Newcastle Ottawa Scale score. Moreover, patients in the low ALI group had an obviously decreased disease-free survival compared to these in the high ALI group (HR=1.47; 95%CI: 1.28-1.68; P&lt;0.001; I2 = 0%).ConclusionBased on existing evidence, the ALI could act as a valuable predictor of POCs and long-term outcomes in patients with GI cancer. However, the heterogeneity in the ALI cut-off value among studies should be considered when interpreting these findings

E-[4-(β-d-Allopyranos­yloxy)phen­yl]-1-(4-chloro­phen­yl)prop-2-enone ethanol solvate

The title compound, C21H21ClO7·C2H5OH was synthesized by the condensation reaction between helicid [systematic name: 4-(β-d-allopyranos­yloxy)benzaldehyde] and 4-chloro­aceto­phen­one in ethanol. In the mol­ecular structure, the pyran­oside ring adopts a chair conformation. In the crystal structure, the molecules are linked by inter­molecular O—H⋯O hydrogen bonds involving the OH groups from the pyran­oside unit and from the ethanol solvent mol­ecule