1,846 research outputs found

    Properties of gapped systems in AdS/BCFT

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    We study the conductivities and entanglement structures of two different holographic gapped systems at zero density in the presence of boundaries within AdS/BCFT. The first gapped system is described by the Einstein-scalar gravity and the second one is the dual of AdS soliton geometry. We show that in both these two systems the bulk and boundary conductivities along the spatial direction of the boundary of BCFT are trivial. For the first system, when we increase the size of the subsystem the renormalized entanglement entropy is always non-negative and monotonically decreasing with discontinuous, or continuous, or smooth behavior, depending on the effective tension of the brane. While for the AdS soliton with a boundary, the renormalized entanglement entropy only exhibits a discontinuous drop when we increase the size of the subsystem.Comment: 36 pages, 17 figures, published versio

    An Efficient Plot Fusion Method for High Resolution Radar Based on Contour Tracking Algorithm

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    With the development of radar system, the problem of enormous raw data has drawn much attention. A plot fusion method based on contour tracking algorithm is proposed to detect extended targets in a radar image. Firstly, the characteristic of radar image in complex environment is revealed. Then, the steps of traditional method, region growing method, and the proposed method are introduced. Meanwhile, the algorithm of tracking the contour of an extended target is illustrated in detail. It is not necessary to scan all the plots in the image, because the size of target is considered in the proposed method. Therefore, the proposed method is much more efficient than several existing methods. Lastly, the performance of several methods is tested using the raw data of two scenarios in real world. The experiment results show that the proposed method is practical and most likely to satisfy the real-time requirement in various complex environment

    Efeitos citotóxicos de anestesia local com lidocaína/ropivacaína em linhagens celulares de melanoma humano

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    ResumoJustificativaOs anestésicos locais (ALs) são geralmente considerados como seguros, mas citotoxicidade foi relatada em vários anestésicos locais usados em seres humanos, a qual não é bem investigada. No presente estudo, a citotoxicidade de lidocaína e ropivacaína e da combinação de lidocaína e ropivacaína foi avaliada em linhagens celulares de melanoma humano. Melfalano, um agente alquilante de mostarda nitrogenada, foi usado como um agente de controle para a comparação da atividade citotóxica.MétodosLinhagens celulares de melanoma, A375 e Hs294T foram expostas por uma hora a concentrações diferentes dos agentes mencionados acima. A viabilidade celular após a exposição foi determinada por citometria de fluxo.ResultadosOs ALs investigados mostraram citotoxicidade prejudicial nas linhagens celulares de melanoma estudadas dependente do tempo (p<0,001), da concentração (p<0,001) e do agente. Em ambas as linhagens de células A375 e Hs294T, níveis mínimos de viabilidade celular foram encontrados após 72 horas de exposição a esses agentes. Lidocaína a 2% provocou uma redução das células vitais para 10%±2% e 14%±2% em A375 e Hs294T, respectivamente, após 72 horas de exposição. Ropivacaína a 0,75% após 72 horas reduziu as células viáveis para 15%±3% e 25%±3%, em A375 e Hs294T, respectivamente. A viabilidade celular mínima após exposição de 72 horas para a combinação foi de 10%±2% e 18%±2% em A375 e Hs294T, respectivamente. A viabilidade celular mínima após exposição de 72 horas ao melfalano foi de 8%±1% e 12±2, em A375 e Hs294T, respectivamente.ConclusãoOs ALs têm atividade citotóxica em linhagens de celulares de melanoma humano de modo dependente do tempo, da concentração e do agente. A apoptose nas linhagens celulares foi mediada por meio da atividade das caspases‐3 e caspases‐8.AbstractBackgroundLocal anesthetics (LAs) are generally considered as safe, but cytotoxicity has been reported for several local anesthetics used in humans, which is not well investigated. In the present study, the cytotoxicity of lidocaine, ropivacaine and the combination of lidocaine and ropivacaine were evaluated on human melanoma cell lines. Melphalan, a nitrogen mustard alkylating agent, was used as a control agent for comparison of cytotoxic activity.MethodsMelanoma cell lines, A375 and Hs294T, were exposed to 1h to different concentrations of above agents. Cell‐viability after exposure was determined by flow cytometry.ResultsInvestigated LAs showed detrimental cytotoxicity on studied melanoma cell lines in time‐ (p<0.001), concentration‐ (p<0.001), and agent dependant. In both A375 and Hs294T cell lines, minimum cell viability rates were found after 72h of exposure to these agents. Lidocaine 2% caused a reduction of vital cells to 10%±2% and 14%±2% in A375 and Hs294T, respectively after 72h of exposure. Ropivacaine 0.75% after 72h reduced viable cells to 15%±3% and 25%±3% in A375 and Hs294T, respectively. Minimum cell viability after 72h exposure to the combination was 10%±2% and 18%±2% in A375 and Hs294T, respectively. Minimum cell viability after 72h exposure to melphalan was 8%±1% and 12%±2%, in A375 and Hs294T, respectively.ConclusionLAs have cytotoxic activity on human melanoma cell lines in a time‐, concentration‐ and agent‐dependant manner. Apoptosis in the cell lines was mediated through activity of caspases‐3 and caspases‐8

    A study of photoluminescence properties and performance improvement of Cd-doped ZnO quantum dots prepared by the sol–gel method

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    In the present work, ZnO quantum dots (QDs) have been prepared by the sol–gel method, and the performance of the QDs has been improved. The effect of Cd concentration on the structural and luminescent properties of the QDs, as well as the effect of the mass ratio of trioctylphosphine oxide (TOPO)/octadecylamine (ODA), has been investigated. The ZnO and Cd-doped ZnO QDs have hexagonal wurtzite structures and are 3 to 6 nm in diameter. When the Cd content was increased, the QD particle size was reduced; this effect was confirmed in the corresponding ultraviolet–visible spectra. The fluorescence intensity was simultaneously enhanced significantly. Both the UV and fluorescence spectra were blue-shifted. The luminous intensity was further enhanced when the QDs were modified with TOPO/ODA. Fourier transform infrared and X-ray diffraction techniques proved that the polymer successfully coated the surfaces of the QDs. A TOPO/ODA mass ratio of 1:2 was determined to result in the best optical performance among the different ratios examined. The results showed that the described synthetic method is appropriate for the preparation of doped QDs with high-fluorescence quantum efficiency

    Ellipticity dependence of 400 nm-driven high harmonic generation

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    We studied the dependence of high harmonic generation efficiency on the ellipticity of 400 nm driving laser pulses at 7.7 x 10(14) W/cm(2) and compared it with the 800 nm driving laser under the same conditions. The measured decrease of high harmonic yield with the ellipticity of the 400 nm laser is similar to 1.5 times slower that of the 800 nm, which agrees well with theoretical predictions based on a semi-classical model. The results indicate that it is feasible to use the generalized double optical gating with 400 nm lasers for extracting single attosecond pulses with high efficiency

    Dependence of high-order-harmonic-generation yield on driving-laser ellipticity

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    High-order-harmonic-generation yield is remarkably sensitive to driving laser ellipticity, which is interesting from a fundamental point of view as well as for applications. The most well-known example is the generation of isolated attosecond pulses via polarization gating. We develop an intuitive semiclassical model that makes use of the recently measured initial transverse momentum of tunneling ionization. The model is able to predict the dependence of the high-order-harmonic yield on driving laser ellipticity and is in good agreement with experimental results and predictions from a numerically solved time-dependent Schrodinger equation
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