Hematological results from primary blood samples (n = 10) that were used to derive blood preparations.

<p>Hematological results from primary blood samples (n = 10) that were used to derive blood preparations.</p

Coefficients of multivariate regression models for mtDNAcn(WB) measured in blood preparations (n = 46).

<p>Coefficients of multivariate regression models for mtDNAcn(WB) measured in blood preparations (n = 46).</p

Scatter plot of the change of mtDNAcn(WB) per unit increase of the platelets/leukocyte ratio.

<p>This scatter plot shows the change of mtDNAcn(WB) per unit increase of the platelets/leukocyte ratio. Data from 46 preparations are shown. Individual mtDNAcn(WB) for each preparation are plotted as white circles. The line represents the fit of a linear model (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0163770#pone.0163770.t003" target="_blank">Table 3</a>, Model 6). mtDNAcn(WB): mitochondrial DNA copy number measured in whole blood.</p

Hematological results from primary blood samples (n = 10) that were used to derive blood preparations.

<p>Hematological results from primary blood samples (n = 10) that were used to derive blood preparations.</p

Platelet count, Leukocyte count and mtDNAcn(WB) distributions in all subjects from the AWHS cohort study (n = 3389).

<p>Platelet count, Leukocyte count and mtDNAcn(WB) distributions in all subjects from the AWHS cohort study (n = 3389).</p

Characteristics of the study population with and without metabolic syndrome.

<p>Average and standard deviation of clinical, physical, and biochemical parameters. P values were calculated from t-tests.</p><p>*n = 3136 due to missing values.</p><p>^†BP: Blood Pressure.</p><p>^‡HOMA-IR: Homeostatic Model Assessment—Insulin Resistance.</p><p>Characteristics of the study population with and without metabolic syndrome.</p

ROC curves of HbA1c, insulin, glycemia and HOMA-IR for insulin resistance and criteria clusters.

<p>ROC curves for detecting insulin resistance, the metabolic syndrome, 2 or more, and 3 or more criteria for the metabolic syndrome other than the high glucose criterion. The small circles indicate the sensitivity and specificity when using the tertiles of each variable as cut-offs. For insulin resistance, the HOMA-IR curve can not be seen as it lies exactly at the left and upper borders.</p

ROC curves of HbA1c, insulin, glycemia and HOMA-IR for metabolic syndrome criteria.

<p>ROC curves for detecting individually each metabolic syndrome criteria. The small circles indicate the sensitivity and specificity when using the tertiles of each variable as cut-offs. For high glucose, the glycemia curve can not be seen as it lies exactly at the left and upper borders.</p