チイキ ノ トクセイ オ イカシタ チュウガッコウ ビジュツカ ノ キョウイク ナイヨウ : ビジュツ キョウイク ノ ラーニング リソース トシテノ トクシマ ブンカザイ タンキュウ

In Japan\u27s education that has a centralized character, how to reflect the environment surrounding schools into the educational contents is one of the important themes. Regarding the contents of art subject, it is often taken up as masterpieces of Western art and Japanese national treasures in the domain of appreciation. As the subject of learning, Masterpieces of Western art and the national treasure of Japan occupy the center position. Although we have no objection of learning on such learning subjects to guarantee the quality of education, we will emphasize the value of cultural properties more familiar to our students on this paper. Because we recognize that Japanese education is at a turning point shifting to so−called "active learning" inducing learners\u27 subjective studies. Based on these recognitions, we\u27ll examine the reason why learning about the familiar cultural properties promoting the subjective learning. In order to avoid showing only abstract debate and to suggest proposal for teaching materialization, Tokushima cultural heritage will be taken up as learning resources and we\u27ll discuss the methods and procedures how to incorporate them into the content of art classes in junior high school

ズガ コウサクカ カラ ビジュツカ ソシテ ビジュツ エ ソノ ヒロガリ ト ツナガリ ノ ケントウ : キョウカショ デ オシエラレテイル コト オシエラレテイナイ コト オシエルベキ コト

Courses of Study clearly define what to teach in Course of Arts and Crafts, and the manual of Courses of Study concretely explained that in detail. In Course of Arts and Crafts, Teacher proposes activities as "subject matter" which includes contents of instruction. Textbook can be thought of as collection of subject matters. Course of Arts and Crafts is connected to Course of Arts in junior high school in many contents, and the next stage is Arts in culture. In this paper, we will investigate today’s contents of subject matter in Course of Arts and Crafts from the view point of Arts as culture. This investigation explains what is not treated in current Course of Arts and Crafts and what to be treated as Course of Arts and Crafts in future

A Study on Seismic Performance Evaluation and Enhancement of Masonry Buildings

特集2 耐震構造学研究グループ (ERS

An Approach to Improve Intestinal Absorption of Poorly Absorbed Water-Insoluble Components via Niemann Pick C1-Like 1

Dietary and biliary cholesterol absorption contributes to the maintenance of tight control of cholesterol homeostasis. Cholesterol is present as mixed micelles formed by bile salts and phospholipids in the intestinal lumen. Recently, Niemann Pick Cl-Like 1 (NPC1L1) transporter was identified as being critical for cholesterol absorption. However, the uptake mechanism of an enveloped substrate of NPC1L1 in whole lipid emulsion particles remains unclear. In this study, we investigated the uptake mechanism of a substrate of NPC1L1 in lipid emulsion particles. We also investigated whether these particles containing cholesterol can improve the intestinal absorption of other lipophilic components via NPC1L1. The uptake of lysophosphatidylcholine (LPC)-4,4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-indacene-3-propionic acid saccinimidyl ester (BODIPY), a fluorescently labeled phospholipid, in lipid emulsion particles containing cholesterol (1 mu m) was significantly increased compared to that without cholesterol in Caco-2 cells. On the other hand, its increased uptake was significantly inhibited by ezetimibe, a selective inhibitor of NPC1L1. These results suggested that not only cholesterol but also some components in lipid emulsion particles are taken up into enterocytes via NPC1L1. We also examined an approach to improve intestinal absorption of a poorly absorbed water-insoluble component, coenzyme Q10 (CoQ10), by this mechanism. The uptake of CoQ10 in lipid emulsion particles containing cholesterol was significantly increased compared to that without cholesterol. Its increased uptake was significantly inhibited by ezetimibe. Though it is still not clear whether CoQ10 is a substrate of NPC1L1, there is a potential for improvement of the absorption of poorly absorbed components by lipid emulsion particles containing cholesterol