Spatial modelling of malaria prevalence associated with geographical factors in Houet province of Burkina Faso, West Africa

International audienceMalaria is a permanent threat to health in western Burkina Faso. Research has shown that geographical variables contribute to the spatial distribution in its transmission. The objective of this study is to assess the relationship between malaria prevalence and potential explanatory geographical variables in the Houet province in Burkina Faso. Statistics on malaria prevalence registered by health centres in the Houet province in 2017 and potential geographical variables identified through a literature review were collected. An Ordinary Least Squares (OLS) regression was used to identify key geographical variables and to measure their association with malaria while the Getis Ord Gi* index was used to locate malaria hotspots. The results showed that average annual temperature, vegetation density, percentage of clay in the soil, total annual rainfall and distance to the nearest waterbody are the main variables associated with malaria prevalence. These variables account for two-thirds of the spatial variability of malaria prevalence observed in Houet province. The intensity and direction of the relationship between malaria prevalence and geographical factors vary according to the variable. Hence, only vegetation density is positively correlated with malaria prevalence. Average temperature, for soil clay content, annual rainfall and for distance to the nearest water body are negatively correlated with the disease prevalence. These results show that even in an endemic area, malaria prevalence has significant spatial variation. The results could contribute to the choice of intervention sites, as this choice is crucial for reducing the malaria burden

Diabetes knowledge and associated factors in adolescents and young adults with type 1 diabetes in Ouagadougou (Burkina Faso)

Abstract Background Type 1 diabetes (T1D) in youth is becoming a public health problem in Sub-Saharan Africa, including Burkina Faso. However, little is known about the level of knowledge of these patients on T1D. This study aimed to evaluate the knowledge of diabetes in adolescents and young adults about the disease, and identify the factors associated in Burkina Faso. Methods A cross-sectional survey was conducted from April to June 2020 among youth with T1D, aged 10 to 30 years, and regularly followed in the internal medicine department of Yalgado Ouedraogo University Hospital of Ouagadougou, Burkina Faso. Data were collected using the French AJD (Aide aux Jeunes Diabétiques) validated diabetes knowledge and skills (DKS) questionnaire designed to test participants’ accuracy in knowledge about six different themes of T1D, as generalities of diabetes, hypoglycemia and hyperglycemia, management of insulin treatment, and self-monitoring blood glucose (SMBG). DKS level was determined by calculating the scores, and univariate and multivariate logistic regression were used to explore factors influencing DKS scores. This level was classified as insufficient or low ≤ 25/50, regular 26–39/50, and adequate or good ≥ 40/50. Results Sixty-three participants with a mean age of 19.05 years and a sex ratio (W/M) of 1.17 were included in our study. The mean HbA1c level was 9.79%, and 43 (68.23%) patients had an insufficient DKS level. The mean global DKS score of correct answers was 23.63/50. The percentage of correct answers was respectively 50% for the item “generalities of diabetes”, 32.4% for the item “hypoglycemia and hyperglycemia”, 67.72% for the item “diet”, 37.34% for the item “management of insulin treatment” and 44.97% for the item “SMBG”. In univariate analysis, a better patient DKS level was associated with university education and long duration of diabetes care follow-up (> 10 years, p < 0.05). Only increasing age remain associated with a better knowledge score (p < 0.05) in multivariate analysis. Conclusion This study is an important first step in identifying areas for intervention efforts about therapeutic education for youth with type I diabetes in Burkina Faso