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The presence of organophosphorus compounds (OPs) in the environmental counterparts has become an important problem because of their toxicity. In this study, the photocatalytic degradation reactions of the three OPs with hydroxyl radical were investigated by both experimental and quantum chemical methods. Photocatalytic degradation kinetics of the examined organophosphorus compounds were investigated under UV-A irradiation using TiO2 as the photocatalyst. The effects of the initial concentrations on the degradation rate have been examined. There was an observable loss of OPs in the presence of TiO2 photocatalyst under UV-A at 0.2 g TiO2 per 100 mL. The quantum chemical calculations have been carried out by the density functional theory (DFT) at B3LYP/6-31g(d) level. The reaction pathways were modelled to find the most probable mechanism for OPs with the OH radical and to determine the primary intermediates. The rate constants of the eight reaction paths were calculated by the transition state theory. Conductor-like polarizable continuum model (CPCM) was used as the solvation model with the intention of understanding the water effect. The theoretical results were in agreement with experimental ones. © 2021 Serbian Chemical Society. All rights reserved.18,164Acknowledgement. The authors of this research has greatfully acknowledgemented to financially support of Tekirdag Namık Kemal University Research Project with the project number of NKUBAP.01.GA.18.164

Anatomical evaluation of nasopalatine canal on cone beam computed tomography images

Background: Nasopalatine canal (NPC) (incisive canal) morphology is important for oral surgery techniques carried out on the maxilla, in the treatment of naso- palatine cyst, palatal pathologies that require a surgical intervention. Materials and methods: The morphology of NPC was classified in sagittal, coronal and axial planes on the cone beam computed tomography (CBCT). The length of NPC was found by measuring the distance between the mid-points of nasopalatine foramen and incisive foramen. The numbers, shapes and diameters of incisive and nasopalatine foramina were examined. Nasopalatine angle present between the NPC and the palate and anterior to the NPC was measured.  Results: In the sagittal plane, the shape of NPC was classified in six groups: 26.7% hourglass, 14.7% cone, 13.3% funnel, 16.0% banana, 28.7% cylindrical and 0.7% reverse-cone-shaped. In the coronal plane, shape of NPC was classified in three groups: 63.3% Y-shaped, 36.0% single canal, 0.7% double canal and external border of NPC was classified in four groups: 26.7% U, 28.7% Y, 44.0% V and 0.7% reverse-V-shaped. In the axial plane, the shape of nasopalatine foramen, incisive foramen and NPC at the mid-level was evaluated. The shape of the canal was detected as four types at three evaluated levels: round, oval, heart- and triangle-shaped. It was seen in every three axial planes that the round group is more than the others.  Conclusions: The morphological properties and variations of NPC should be con- sidered with a correct radiological evaluation so as to prevent the complications and improper practices in local anaesthesia, maxillary surgery and implant surgery practices. Especially dentists, otolaryngologist and plastic surgeons need to know the anatomy and variations of NPC.

Measurements of Gd 152 (p,γ) Tb 153 and Gd 152 (p,n) Tb 152 reaction cross sections for the astrophysical γ process

The total cross sections for the Gd152(p,γ)Tb153 and Gd152(p,n)152Tb reactions have been measured by the activation method at effective center-of-mass energies 3.47≤Ec.m.eff≤7.94 MeV and 4.96≤Ec.m.eff≤7.94 MeV, respectively. The targets were prepared by evaporation of 30.6% isotopically enriched Gd152 oxide on aluminum backing foils, and bombarded with proton beams provided by a cyclotron accelerator. The cross sections were deduced from the observed γ-ray activity, which was detected off-line by an HPGe detector in a low background environment. The results are presented and compared with predictions of statistical model calculations. This comparison supports a modified optical proton+Gd152 potential suggested earlier.Peer reviewedFinal Accepted Versio

Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: Noninvasive creation of localized heart defects

Yalçın, Hüseyin Çağatay (Dogus Author)Embryonic heart formation is driven by complex feedback between genetic and hemodynamic stimuli. Clinical congenital heart defects (CHD), however, often manifest as localized microtissue malformations with no underlying genetic mutation, suggesting that altered hemodynamics during embryonic development may play a role. An investigation of this relationship has been impaired by a lack of experimental tools that can create locally targeted cardiac perturbations. Here we have developed noninvasive optical techniques that can modulate avian cardiogenesis to dissect relationships between alterations in mechanical signaling and CHD. We used two-photon excited fluorescence microscopy to monitor cushion and ventricular dynamics and femtosecond pulsed laser photoablation to target micrometer-sized volumes inside the beating chick hearts. We selectively photoablated a small (∼100 μm radius) region of the superior atrioventricular (AV) cushion in Hamburger-Hamilton 24 chick embryos. We quantified via ultrasound that the disruption causes AV regurgitation, which resulted in a venous pooling of blood and severe arterial constriction. At 48 h postablation, quantitative X-ray microcomputed tomography imaging demonstrated stunted ventricular growth and pronounced left atrial dilation. A histological analysis demonstrated that the laser ablation produced defects localized to the superior AV cushion: a small quasispherical region of cushion tissue was completely obliterated, and the area adjacent to the myocardial wall was less cellularized. Both cushions and myocardium were significantly smaller than sham-operated controls. Our results highlight that two-photon excited fluorescence coupled with femtosecond pulsed laser photoablation should be considered a powerful tool for studying hemodynamic signaling in cardiac morphogenesis through the creation of localized microscale defects that may mimic clinical CHD

Measurements of proton induced reaction cross sections on 120Te for the astrophysical p-process

The total cross sections for the 120Te(p,gamma)121I and 120Te(p,n)120I reactions have been measured by the activation method in the effective center-of-mass energies between 2.47 MeV and 7.93 MeV. The targets were prepared by evaporation of 99.4 % isotopically enriched 120Te on Aluminum and Carbon backing foils, and bombarded with proton beams provided by the FN tandem accelerator at the University of Notre Dame. The cross sections and $S$ factors were deduced from the observed gamma ray activity, which was detected off-line by two Clover HPGe detectors mounted in close geometry. The results are presented and compared with the predictions of statistical model calculations using the codes NON-SMOKER and TALYS.Comment: 17 pages, 5 figures, 5 tables, regular articl

Mobility Strategy of Multi-Limbed Climbing Robots for Asteroid Exploration

Mobility on asteroids by multi-limbed climbing robots is expected to achieve our exploration goals in such challenging environments. We propose a mobility strategy to improve the locomotion safety of climbing robots in such harsh environments that picture extremely low gravity and highly uneven terrain. Our method plans the gait by decoupling the base and limbs' movements and adjusting the main body pose to avoid ground collisions. The proposed approach includes a motion planning that reduces the reactions generated by the robot's movement by optimizing the swinging trajectory and distributing the momentum. Lower motion reactions decrease the pulling forces on the grippers, avoiding the slippage and flotation of the robot. Dynamic simulations and experiments demonstrate that the proposed method could improve the robot's mobility on the surface of asteroids.Comment: Submitted version of paper accepted for presentation at the CLAWAR 2023 (26th International Conference on Climbing and Walking Robots and the Support Technologies for Mobile Machines

Relationship of vascular variations with liver remnant volume in living liver transplant donors

Background: In this study, we investigated the relationship between the portal vein and hepatic artery variations and the remaining liver volume in living donors in liver transplantation.Materials and methods: In the study, triphasic abdominal computed tomography images of 180 live liver donor candidates were analysed retrospectively. Portal veins were divided into four groups according to the Nakamura classification and seven groups according to the Michels classification. The relationship between vascular variations and remnant liver volume was compared statistically.Results: According to the Nakamura classification, there were 143 (79.4%) type A, 23 (12.7%) type B, 7 (3.9%) type C and 7 (3.9%) type D cases. Using the Michels classification, 129 (71%) type 1, 12 (6.7%) type 2, 24 (13%) type 3, 2 (2.2%) type 4, 10 (5.6%) type 5, 1 (0.6%) type 6, and 2 (1.1%) type 7 cases were detected. There was no significant difference in the percentage of the remaining volume of the left liver lobe between the groups (p = 0.055, p = 0.207, respectively).Conclusions: Variations in the hepatic artery and portal vein do not affect the remaining liver volume in liver transplantation donors

High precision 113In(α,α)113In elastic scattering at energies near the Coulomb barrier for the astrophysical γ process

Background: The γ process in supernova explosions is thought to explain the origin of proton-rich isotopes between Se and Hg, the so-called p nuclei. The majority of the reaction rates for γ process reaction network studies have to be predicted in Hauser-Feshbach statistical model calculations using global optical potential parametrizations. While the nucleon+nucleus optical potential is fairly well known, for the α+nucleus optical potential several different parametrizations exist and large deviations are found between the predictions calculated using different parameter sets.Purpose: By the measurement of elastic α-scattering angular distributions at energies around the Coulomb barrier a comprehensive test for the different global α+nucleus optical potential parameter sets is provided. Methods: Between 20∘ and 175∘ complete elastic alpha scattering angular distributions were measured on the 113In p nucleus with high precision at Ec.m.=15.59 and 18.82 MeV. Results: The elastic scattering cross sections of the 113In(α,α)113In reaction were measured for the first time at energies close to the astrophysically relevant energy region. The high precision experimental data were used to evaluate the predictions of the recent global and regional α+nucleus optical potentials. Parameters for a local α+nucleus optical potential were derived from the measured angular distributions. Conclusions: Predictions for the reaction cross sections of 113In(α,γ)117Sb and 113In(α,n)116Sb at astrophysically relevant energies were given using the global and local optical potential parametrizations.Peer reviewe

An ex-ovo chicken embryo culture system suitable for imaging and microsurgery applications

Yalçın, Hüseyin Çağatay (Dogus Author)Understanding the relationships between genetic and microenvironmental factors that drive normal and malformed embryonic development is fundamental for discovering new therapeutic strategies. Advancements in imaging technology have enabled quantitative investigation of the organization and maturing of the body plan, but later stage embryonic morphogenesis is less clear. Chicken embryos are an attractive vertebrate animal model system for this application because of its ease of culture and surgical manipulation. Early embryos can be cultured for a short time on filter paper rings, which enables complete optical access for cell patterning and fate studies. Studying advanced developmental processes such as cardiac morphogenesis are traditionally performed through a window of the eggshell, but this technique limits optical access due to window size. We previously developed a simple method to culture whole embryos ex-ovo on hexagonal weigh boats for up to 10 days, which enabled high resolution imaging via ultrasonography. These cultures were difficult to transport, limiting the types of imaging tools available for live experiments. We here present an improved shell-less culture system with a cost-effective, portable environmental chamber. Eggs were cracked onto a hammock created by a polyurethane membrane (cling wrap) affixed circumferentially to a plastic cup partially filled with sterile water. The dimensions of the circumference and depth of the hammock were both critical to maintain surface tension, while the mechanics of the hammock and water beneath helped dampen vibrations induced by transportation. A small footprint circulating water bath was also developed to enable continuous temperature control during experimentation. We demonstrate the ability to culture embryos in this way for at least 14 days without morphogenic defect or delay and employ this system in several microsurgical and imaging applications