Testing Higgs models via the H±W∓ZH^\pm W^\mp Z vertex by a recoil method at the International Linear Collider

In general, charged Higgs bosons $H^\pm$ appear in non-minimal Higgs models. The $H^\pm W^\mp Z$ vertex is known to be related to the violation of the global symmetry (custodial symmetry) in the Higgs sector. Its magnitude strongly depends on the structure of the exotic Higgs models which contain higher isospin $SU(2)_L$ representations such as triplet Higgs bosons. We study the possibility of measuring the $H^\pm W^\mp Z$ vertex via single charged Higgs boson production associated with the $W^\pm$ boson at the International Linear Collider (ILC) by using the recoil method. The feasibility of the signal $e^+e^-\to H^\pm W^\mp \to \ell \nu jj$ is analyzed assuming the polarized electron and positron beams and the expected detector performance for the resolution of the two-jet system at the ILC. The background events can be reduced to a considerable extent by imposing the kinematic cuts even if we take into account the initial state radiation. For a relatively light charged Higgs boson whose mass $m_{H^\pm}$ is in the region of 120-130 GeV $< m_{H^\pm} < m_W+m_Z$, the $H^\pm W^\mp Z$ vertex would be precisely testable especially when the decay of $H^\pm$ is lepton specific. The exoticness of the extended Higgs sector can be explored by using combined information for this vertex and the rho parameter.Comment: 22 pages, 23 figure

Radiative corrections to electroweak parameters in the Higgs triplet model and implication with the recent Higgs boson searches

We study radiative corrections to the electroweak parameters in the Higgs model with the Y=1 triplet field, which is introduced in the scenario of generating neutrino masses based on the so-called type II seesaw mechanism. In this model, the rho parameter deviates from unity at the tree level. Consequently, the electroweak sector of the model is described by the four input parameters such as $\alpha_{\text{em}}$, $G_F$, $m_Z$ and $\sin^2\theta_W$. We calculate the one loop contribution to the W boson mass as well as to the rho parameter in order to clarify the possible mass spectrum of the extra Higgs bosons under the constraint from the electroweak precision data. We find that the hierarchical mass spectrum among $H^{\pm\pm}$, $H^{\pm}$ and $A$ (or $H$) is favored by the precision data especially for the case of $m_A$ $(\simeq m_H)>m_{H^+}>m_{H^{++}}$, where $H^{\pm\pm}$, $H^{\pm}$, $A$ and $H$ are the doubly-charged, singly-charged, CP-odd and CP-even Higgs bosons mainly originated from the triplet field. We also discuss phenomenological consequences of such a mass spectrum with relatively large mass splitting. The decay rate of the Higgs boson decay into two photons is evaluated under the constraint from the electroweak precision data, regarding the recent Higgs boson searches at the CERN LHC.Comment: 17 pages, 23 figures, version published in PRD, title slightly modifie

Models of Yukawa interaction in the two Higgs doublet model, and their collider phenomenology

Possible models of Yukawa interaction are discussed in the two Higgs doublet model (THDM) under the discrete symmetry imposed to avoid the flavor changing neutral current at the leading order. It is known that there are four types of such models corresponding to the possible different assignment of charges for the discrete symmetry on quarks and leptons. We first examine decay properties of Higgs bosons in each type of the models, and summarize constraints on the models from current experimental data. We then shed light on the differences among these models in collider phenomenology. In particular, we mainly discuss so-called the Type-II THDM and the Type-X THDM. The Type-II THDM corresponds to the model with the same Yukawa interaction as the minimal supersymmetric standard model (MSSM). On the other hand, in the Type-X THDM, additional Higgs bosons can predominantly decay into leptons. This scenario may be interesting because of the motivation for a light charged Higgs boson scenario such as in the TeV scale model of neutrino, dark matter and baryogenesis. We study how we can distinguish the Type-X THDM from the MSSM at the Large Hadron Collider and the International Linear Collider.Comment: 33 pages, 41 eps files, version accepted for publication in Physical Review

The antecedents of biliary cancer: a primary care case–control study in the United Kingdom

In a case–control study using a large UK primary care database, we found that non-steroidal anti-inflammatory drugs had no protective effect against biliary carcinomas (cholangiocarcinoma and gall bladder cancer). Increased risks were observed for cigarette smoking, diabetes, gallstone disease and obesity

Decoupling property of the supersymmetric Higgs sector with four doublets

In supersymmetric standard models with multi Higgs doublet fields, selfcoupling constants in the Higgs potential come only from the D-terms at the tree level. We investigate the decoupling property of additional two heavier Higgs doublet fields in the supersymmetric standard model with four Higgs doublets. In particular, we study how they can modify the predictions on the quantities well predicted in the minimal supersymmetric standard model (MSSM), when the extra doublet fields are rather heavy to be measured at collider experiments. The B-term mixing between these extra heavy Higgs bosons and the relatively light MSSM-like Higgs bosons can significantly change the predictions in the MSSM such as on the masses of MSSM-like Higgs bosons as well as the mixing angle for the two light CP-even scalar states. We first give formulae for deviations in the observables of the MSSM in the decoupling region for the extra two doublet fields. We then examine possible deviations in the Higgs sector numerically, and discuss their phenomenological implications.Comment: 26 pages, 24 figures, text sligtly modified,version to appear in Journal of High Energy Physic

A Novel Adaptive Method for the Analysis of Next-Generation Sequencing Data to Detect Complex Trait Associations with Rare Variants Due to Gene Main Effects and Interactions

There is solid evidence that rare variants contribute to complex disease etiology. Next-generation sequencing technologies make it possible to uncover rare variants within candidate genes, exomes, and genomes. Working in a novel framework, the kernel-based adaptive cluster (KBAC) was developed to perform powerful gene/locus based rare variant association testing. The KBAC combines variant classification and association testing in a coherent framework. Covariates can also be incorporated in the analysis to control for potential confounders including age, sex, and population substructure. To evaluate the power of KBAC: 1) variant data was simulated using rigorous population genetic models for both Europeans and Africans, with parameters estimated from sequence data, and 2) phenotypes were generated using models motivated by complex diseases including breast cancer and Hirschsprung's disease. It is demonstrated that the KBAC has superior power compared to other rare variant analysis methods, such as the combined multivariate and collapsing and weight sum statistic. In the presence of variant misclassification and gene interaction, association testing using KBAC is particularly advantageous. The KBAC method was also applied to test for associations, using sequence data from the Dallas Heart Study, between energy metabolism traits and rare variants in ANGPTL 3,4,5 and 6 genes. A number of novel associations were identified, including the associations of high density lipoprotein and very low density lipoprotein with ANGPTL4. The KBAC method is implemented in a user-friendly R package