Financial Analysis and Intercompany Comparison

The goal of this diploma thesis is to prepare financial analyses of three selected construction companies. Results of these analyses will be compared using methods of intercompany comparison. First part of the diploma thesis deals with basics of financial analysis and intercompany comparison, i.e. why, whom and how are both financial analysis and intercompany comparison done and which methods are used. These methods are implemented in the second half of the work. Evaluation of the results are in conclusion

NSE-apoE4, but not GFAP-apoE4, mice have decreased spine density in the auditory cortex at 19–21 months of age.

<p>(<i>A</i>) Representative images of dendrites from the auditory cortex of NSE-apoE3, NSE-apoE4, apoE3-KI, apoE4-KI, GFAP-apoE3, or GFAP-apoE4 mouse brains. (<i>B</i>) Quantification of total spine density in the auditory cortex, combining AO+BS spines. (<i>C</i>) Number of AO and BS spines in the auditory cortex. Values are mean ± SEM, n = 20–24 neurons from 3–5 mice for each group. **<i>p</i><0.01.</p

Cellular source of apoE influences dendrite number and length in the entorhinal cortex at 19–21 months of age.

<p>(<i>A</i>) A representative Golgi-stained image of a pyramidal neuron from the entorhinal cortex. (<i>B</i>) Quantification of the total number of entorhinal cortex dendrites, combining AO+BS dendrites. (<i>C</i>) Number of AO and BS dendrites in the entorhinal cortex. (<i>D</i>) Quantification of the total length of entorhinal cortex dendrites, combining AO+BS dendrites. (<i>E</i>) Length of AO and BS dendrites in the entorhinal cortex. Values are mean ± SEM, n = 13–15 neurons from 3–5 mice for each group. *<i>p</i><0.05.</p

Cellular source of apoE influences dendrite number and length in the auditory cortex at 19–21 months of age.

<p>(<i>A</i>) A representative Golgi-stained image of a pyramidal neuron from the auditory cortex. (<i>B</i>) Quantification of the total number of auditory cortex dendrites, combining AO+BS dendrites. (<i>C</i>) Number of AO and BS dendrites in the auditory cortex. (<i>D</i>) Quantification of the total length of auditory cortex dendrites, combining AO+BS dendrites. (<i>E</i>) Number of AO and BS dendrites in the auditory cortex. Values are mean ± SEM, n = 13–15 neurons from 3–5 mice for each group. *<i>p</i><0.05, **<i>p</i><0.01.</p

Quantification of spine subtypes in the entorhinal cortex (EC) in different apoE mouse models at 19–21 months of age.

<p>(<i>A–H</i>) Averaged densities of stubby (<i>A–B</i>), thin (<i>C–D</i>), mushroom (<i>E–F</i>), and filopodia (<i>G–H</i>) type protrusions in the entorhinal cortex for all genotypes. Values are mean ± SEM, n = 20–33 neurons from 3–5 mice for each group. **<i>p</i><0.01.</p

Quantification of spine subtypes in the CA1 region of the hippocampus in different apoE mouse models at 19–21 months of age.

<p>(<i>A–H</i>) Averaged densities of stubby (<i>A–B</i>), thin (<i>C–D</i>), mushroom (<i>E–F</i>), and filopodia (<i>G–H</i>) type protrusions in the CA1 region for all genotypes. Values are mean ± SEM, n = 20–33 neurons from 3–5 mice for each group. *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001.</p

Quantification of spine subtypes in the auditory cortex (AC) in different apoE mouse models at 19–21 months of age.

<p>(<i>A–H</i>) Averaged densities of stubby (<i>A–B</i>), thin (<i>C–D</i>), mushroom (<i>E–F</i>), and filopodia (<i>G–H</i>) type protrusions in the auditory cortex for all genotypes. Values are mean ± SEM, n = 20–33 neurons from 3–5 mice for each group. *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001.</p

NSE-apoE4 and apoE4-KI, but not GFAP-apoE4, mice have reduced dendritic spine density in the entorhinal cortex at 19–21 months of age.

<p>(<i>A</i>) Representative images of dendrites with spines from the entorhinal cortex of NSE-apoE3, NSE-apoE4, apoE3-KI, apoE4-KI, GFAP-apoE3, or GFAP-apoE4 mouse brains. (<i>B</i>) Quantification of total spine density in the entorhinal cortex, combining AO+BS spines. (<i>C</i>) Number of AO and BS spines in the CA1. Values are mean ± SEM, n = 20–25 neurons from 3–5 mice for each group. *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001.</p

Cellular source of apoE influences dendrite number and length in the CA1 region of the hippocampus at 19–21 months of age.

<p>(<i>A</i>) A representative Golgi-stained image of a CA1 pyramidal neuron. (<i>B</i>) Quantification of the total number of CA1 dendrites, combining AO+BS dendrites. (<i>C</i>) Number of AO and BS dendrites in the CA1. (<i>D</i>) Quantification of the total length of CA1 dendrites, combining AO+BS dendrites. (<i>E</i>) Length of AO and BS dendrites in the CA1. Values are mean ± SEM, n = 13–15 neurons from 3–5 mice for each group. *<i>p</i><0.05.</p

NSE-apoE4 and apoE4-KI, but not GFAP-apoE4, mice have reduced dendritic spine density in the CA1 region compared to apoE3 counterparts at 19–21 months of age.

<p>(<i>A</i>) Representative images of dendrites with spines from the CA1 region of NSE-apoE3, NSE-apoE4, apoE3-KI, apoE4-KI, GFAP-apoE3, or GFAP-apoE4 mouse brains. (<i>B</i>) Quantification of total spine density in the CA1 region, combining AO+BS spines. (<i>C</i>) Number of AO and BS spines in the CA1. Values are mean ± SEM, n = 28–33 neurons from 3–5 mice for each group. **<i>p</i><0.01, ***<i>p</i><0.001.</p