1,375 research outputs found

    The role of newly born magnetars in gamma-ray burst X-ray afterglow emission: Energy injection and internal emission

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    Swift observations suggest that the central compact objects of some gamma-ray bursts (GRBs) could be newly born millisecond magnetars. Therefore, considering the spin evolution of the magnetars against r-mode instability, we investigate the role of magnetars in GRB X-ray afterglow emission. Besides modifying the conventional energy injection model, we pay particular attention to the internal X-ray afterglow emission, whose luminosity is assumed to track the magnetic dipole luminosity of the magnetars with a certain fraction. Following a comparison between the model and some selected observational samples, we suggest that some so-called canonical X-ray afterglows including the shallow decay, normal decay, and steeper-than-normal decay phases could be internally produced by the magnetars (possibly through some internal dissipations of the magnetar winds), while the (energized) external shocks are associated with another type of X-ray afterglows. If this is true, then from those internal X-ray afterglows we can further determine the magnetic field strengths and the initial spin periods of the corresponding magnetars. © 2010. The American Astronomical Society. All rights reserved.published_or_final_versio

    The luminosity function of Swift long gamma-ray bursts

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    The accumulation of Swift observed gamma-ray bursts (GRBs) has gradually made it possible to directly derive a GRB luminosity function (LF) from the observational luminosity distribution. However, two complexities are involved: (i) the evolving connection between GRB rate and cosmic star formation rate; and (ii) observational selection effects due to telescope thresholds and redshift measurements. With a phenomenological investigation of these two complexities, we constrain and discriminate two popular competing LF models (i.e. the broken-power-law LF and the single-power-law LF with an exponential cut-off at low luminosities). As a result, we find that the broken-power-law LF may be more favoured by observations, with a break luminosity L b= 2.5 × 10 52ergs -1 and prior- and post-break indices ν 1= 1.72 and ν 2= 1.98. Regarding an extra evolution effect expressed by a factor (1 +z) δ, if the metallicity of GRB progenitors is lower than ~0.1Z ⊙ as expected by some collapsar models, then there may be no extra evolution effect other than the metallicity evolution (i.e. δ approaches zero). Alternatively, if we remove the theoretical metallicity requirement, then a relationship between the degenerate parameters δ and Z max can be found, very roughly, δ~ 2.4(Z max/Z ⊙- 0.06). This indicates that extra evolution could become necessary for relatively high metallicities. © 2011 The Authors Monthly Notices of the Royal Astronomical Society © 2011 RAS.published_or_final_versio

    Native donors and compensation in Fe-doped liquid encapsulated Czochralski InP

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    Undoped and Fe-doped liquid encapsulated Czochralski (LEC) InP has been studied by Hall effect, current-voltage (I-V), and infrared absorption (IR) spectroscopy. The results indicate that a native hydrogen vacancy complex donor defect exists in as-grown LEC InP. By studying the IR results, it is found that the concentration of this donor defect in Fe-doped InP is much higher than that in undoped InP. This result is consistent with the observation that a much higher concentration of Fe 2+ than the apparent net donor concentration is needed to achieve the semi-insulating (SI) property in InP. By studying the I-V and IR results of Fe-doped InP wafers sliced from different positions on an ingot, the high concentration of Fe 2+ is found to correlate with the existence of this hydrogen complex. The concentration of this donor defect is high in wafers from the top of an ingot. Correspondingly, a higher concentration of Fe 2+ can be detected in these wafers. These results reveal the influence of the complex defect on the compensation and uniformity of Fe-doped SI InP materials. © 2001 American Institute of Physics.published_or_final_versio

    Control and Characterization of Individual Grains and Grain Boundaries in Graphene Grown by Chemical Vapor Deposition

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    The strong interest in graphene has motivated the scalable production of high quality graphene and graphene devices. Since large-scale graphene films synthesized to date are typically polycrystalline, it is important to characterize and control grain boundaries, generally believed to degrade graphene quality. Here we study single-crystal graphene grains synthesized by ambient CVD on polycrystalline Cu, and show how individual boundaries between coalescing grains affect graphene's electronic properties. The graphene grains show no definite epitaxial relationship with the Cu substrate, and can cross Cu grain boundaries. The edges of these grains are found to be predominantly parallel to zigzag directions. We show that grain boundaries give a significant Raman "D" peak, impede electrical transport, and induce prominent weak localization indicative of intervalley scattering in graphene. Finally, we demonstrate an approach using pre-patterned growth seeds to control graphene nucleation, opening a route towards scalable fabrication of single-crystal graphene devices without grain boundaries.Comment: New version with additional data. Accepted by Nature Material

    Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed

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    Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural products extracts are commonly highly complex mixtures of active compounds and consequently their purification becomes a particularly challenging task. The development of a purification protocol to extract a single active component from the many hundreds that are often present in the mixture is something that can take months or even years to achieve, thus it is important for the natural product chemist to have, at their disposal, a broad range of diverse purification techniques. Counter-current chromatography (CCC) is one such separation technique utilising two immiscible phases, one as the stationary phase (retained in a spinning coil by centrifugal forces) and the second as the mobile phase. The method benefits from a number of advantages when compared with the more traditional liquid-solid separation methods, such as no irreversible adsorption, total recovery of the injected sample, minimal tailing of peaks, low risk of sample denaturation, the ability to accept particulates, and a low solvent consumption. The selection of an appropriate two-phase solvent system is critical to the running of CCC since this is both the mobile and the stationary phase of the system. However, this is also by far the most time consuming aspect of the technique and the one that most inhibits its general take-up. In recent years, numerous natural product purifications have been published using CCC from almost every country across the globe. Many of these papers are devoted to terpenoids-one of the most diverse groups. Naturally occurring terpenoids provide opportunities to discover new drugs but many of them are available at very low levels in nature and a huge number of them still remain unexplored. The collective knowledge on performing successful CCC separations of terpenoids has been gathered and reviewed by the authors, in order to create a comprehensive document that will be of great assistance in performing future purifications. © 2014 The Author(s)

    Observation of a ppb mass threshoud enhancement in \psi^\prime\to\pi^+\pi^-J/\psi(J/\psi\to\gamma p\bar{p}) decay

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    The decay channel ψπ+πJ/ψ(J/ψγppˉ)\psi^\prime\to\pi^+\pi^-J/\psi(J/\psi\to\gamma p\bar{p}) is studied using a sample of 1.06×1081.06\times 10^8 ψ\psi^\prime events collected by the BESIII experiment at BEPCII. A strong enhancement at threshold is observed in the ppˉp\bar{p} invariant mass spectrum. The enhancement can be fit with an SS-wave Breit-Wigner resonance function with a resulting peak mass of M=186113+6(stat)26+7(syst)MeV/c2M=1861^{+6}_{-13} {\rm (stat)}^{+7}_{-26} {\rm (syst)} {\rm MeV/}c^2 and a narrow width that is Γ<38MeV/c2\Gamma<38 {\rm MeV/}c^2 at the 90% confidence level. These results are consistent with published BESII results. These mass and width values do not match with those of any known meson resonance.Comment: 5 pages, 3 figures, submitted to Chinese Physics

    LPS induces IL-10 production by human alveolar macrophages via MAPKinases- and Sp1-dependent mechanisms

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    <p>Abstract</p> <p>Background</p> <p>IL-10 is a cytokine mainly produced by macrophages that plays key roles in tolerance to inhaled antigens and in lung homeostasis. Its regulation in alveolar macrophages (HAM), the resident lung phagocytes, remains however unknown.</p> <p>Methods</p> <p>The present study investigated the role of intracellular signalling and transcription factors controlling the production of IL-10 in LPS-activated HAM from normal nonsmoking volunteers.</p> <p>Results</p> <p>LPS (1–1000 pg/ml) induced <it>in vitro </it>IL-10 production by HAM, both at mRNA and protein levels. LPS also activated the phosphorylation of ERK, p38 and JNK MAPkinases (immunoblots) and Sp-1 nuclear activity (EMSA). Selective inhibitors of MAPKinases (respectively PD98059, SB203580 and SP600125) and of Sp-1 signaling (mithramycin) decreased IL-10 expression in HAM. In addition, whilst not affecting IL-10 mRNA degradation, the three MAPKinase inhibitors completely abolished Sp-1 activation by LPS in HAM.</p> <p>Conclusion</p> <p>These results demonstrate for the first time that expression of IL-10 in lung macrophages stimulated by LPS depends on the concomitant activation of ERK, p38 and JNK MAPKinases, which control downstream signalling to Sp-1 transcription factor. This study further points to Sp-1 as a key signalling pathway for IL-10 expression in the lung.</p

    The effect of graphene oxide (GO) nanoparticles on the processing of epoxy/glass fiber composites using resin infusion

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    In this paper, the effects of graphene oxide (GO) nanoparticles on glass fiber composite processing by incorporating them into epoxy resin were investigated. GO was synthesized from graphite powder and was mixed with epoxy resin. Three different GO contents of 0.05, 0.1, and 0.2 wt% were used. Epoxy/GO samples were tested for rheology and cure kinetics to evaluate the effects of GO content on important resin infusion processing parameters. The results show that adding GO to neat epoxy resin increased the viscosity and affected the resin cure reaction by reducing the resin gel time. After that, glass fiber composites were prepared using the resin infusion process. Samples with 0.2 wt% GO result in very slow resin infiltration time with premature resin gelation. A 30 % increase in flexural strength and a 21 % increase in flexural modulus are manifested by adding GO as the secondary reinforcement to glass fiber composites

    Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

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    Most human pre-mRNAs are spliced into linear molecules that retain the exon order defined by the genomic sequence. By deep sequencing of RNA from a variety of normal and malignant human cells, we found RNA transcripts from many human genes in which the exons were arranged in a non-canonical order. Statistical estimates and biochemical assays provided strong evidence that a substantial fraction of the spliced transcripts from hundreds of genes are circular RNAs. Our results suggest that a non-canonical mode of RNA splicing, resulting in a circular RNA isoform, is a general feature of the gene expression program in human cells
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