Subclinical hyperthyroidism and dementia: the Sao Paulo Ageing & Health Study (SPAH)

<p>Abstract</p> <p>Background</p> <p>Several epidemiologic studies have shown a possible association between thyroid function and cognitive decline. Our aim was to evaluate the association of subclinical hyperthyroidism and dementia in a population sample of older people</p> <p>Methods</p> <p>A cross-sectional study - São Paulo Ageing & Health Study (SPAH) - in a population sample of low-income elderly people ≥ 65 years-old to evaluate presence of subclinical thyroid disease as a risk factor for dementia. Thyroid function was assessed using thyrotropic hormone and free-thyroxine as well as routine use of thyroid hormones or antithyroid medications. Cases of dementia were assessed using a harmonized one-phase dementia diagnostic procedure by the "10/66 Dementia Research Group" including Alzheimer's disease and vascular dementia. Logistic regression models were used to test a possible association between subclinical hyperthyroidism and dementia.</p> <p>Results and discussion</p> <p>Prevalence of dementia and of subclinical hyperthyroidism were respectively of 4.4% and 3.0%. After age adjustment, we found an association of subclinical hyperthyroidism and any type of dementia and vascular dementia (Odds Ratio, 4.1, 95% Confidence Interval [95% CI] 1.3-13.1, and 5.3 95% CI, 1.1-26.4; respectively). Analyzing data by gender, we found an association of subclinical hyperthyroidism with dementia and Alzheimer's disease only for men (OR, 8.0; 95% CI, 1.5-43.4; OR, 12.4; 95% CI, 1.2-128.4; respectively). No women with subclinical hypothyroidism presented Alzheimer's disease in the sample.</p> <p>Conclusion</p> <p>The results suggest a consistent association among people with subclinical hyperthyroidism and dementia.</p

Revista de Saúde Pública: 50 years disseminating the knowledge in nutrition

ABSTRACT This work describes and comments on articles in the area of Public Health Nutrition published in Revista de Saúde Pública (RSP &#8211; Public Health Journal) from 1967 to 2016. We searched in the PubMed database restricted to the periodical &#8220;Revista de Saúde Pública&#8221; and using terms related to key topics in the area of Public Health Nutrition. We retrieved 742 articles and, after exclusion of duplicates and articles unrelated to the subject, we analyzed 441 articles, grouped according to subject: dental caries, anemia, hypovitaminosis A, macro/micronutrients, malnutrition, nutritional assessment, overweight/obesity, food consumption, low birthweight, and breastfeeding. We observed significant increase in the number of articles published and diversification of subjects addressed over the 50 years, representing the consistent development of the scientific field of Nutrition in Brazil. Since its inception, RSP has played an important role in the dissemination of knowledge about the main nutritional issues in Brazil

Estudo da prevalência das doenças tireoidianas em pacientes tireoidectomizados no Hospital da Santa Casa de Goiânia

OBJETIVO: O Estado de Goiás deixou de ser oficialmente considerado como região endêmica de bócio em 1995. O objetivo deste estudo é verificar a correspondência entre os diagnósticos das doenças tireoidianas (bócio endêmico, tireoidites e câncer), observados nos laudos anátomo-patológicos e nas observações dos inquéritos epidemiológicos. MÉTODO: Estudo retrospectivo de 1399 pacientes submetidos a tireoidectomias na Santa Casa de Misericórdia de Goiânia de 1993 a 2003, e que resultaram em 1610 diagnósticos anátomo-patológicos. RESULTADOS: Os resultados dos exames anátomo-patológicos dos pacientes revelaram: a) adenoma folicular 155 (9,63%); b) outros adenomas 29 (1,8%); c) bócio adenomatoso 87 (5,4%); d) bócio colóide 981 (60,9%); e) carcinoma folicular 36 (2,24%); f) carcinoma indiferenciado 3 (0,19%); g) carcinoma papilífero 93 (5,78%); h) cistos 9 (0,56%); i) bócio difuso tóxico 75 (4,66%); j) outras tireoidites 12 (0,75%); l) outras neoplasias malignas 6 (0,38%) e m) tireoidite linfocítica 124 (7,71%). CONCLUSÕES: O perfil observado com uma prevalência alta de tireoidite linfocítica e carcinoma papilífero se correlaciona realmente com região não endêmica

Aceitação de dietas em ambiente hospitalar Acceptance of hospital food

OBJETIVO: O objetivo do estudo foi avaliar a aceitação de dietas de pacientes internados em um hospital público do município de Florianópolis, Santa Catarina. MÉTODOS: Realizou-se análise dos restos alimentares de pacientes internados em unidades de internação médica durante 15 dias, por meio do índice resto-ingestão. O índice foi determinado por tipos de dieta, classificadas em normal, especial com sal e especial sem sal. Enquetes de satisfação com pacientes avaliaram os fatores que influenciam a aceitação das refeições. RESULTADOS: O peso total distribuído correspondente a 1.877 refeições foi de 868kg e o peso dos restos totalizou 313kg. Foi encontrado um índice resto-ingestão de 36,09% e um retorno de 53,68%, 33,99% e 33,84% de dietas especiais com sal, normais e especiais sem sal respectivamente. A variedade, a quantidade e a apresentação das refeições foram avaliadas de forma positiva. A temperatura e o uso de temperos foram os aspectos de menor satisfação, representando 43,00% e 34,30%, respectivamente, para os critérios de regular a ruim. O índice resto-ingestão encontrado (36,09%) estava acima do aceitável para uma população enferma (20,00%), demonstrando uma perda considerável de alimentos. CONCLUSÃO: A partir dos resultados, observou-se a necessidade de avaliar os processos envolvidos na produção dessas refeições e de elaborar estratégias que estimulem a ingestão alimentar do paciente.<br>OBJECTIVE: This study assessed patients' acceptance of hospital foods in a public hospital located in Florianópolis, Santa Catarina, Brazil. METHODS: The leftover-ingestion index was used to analyze the volume of leftovers of hospitalized patients during 15 days. The index was determined by diet type: normal, special with salt and special without salt. Satisfaction questionnaires were administered to the patients and the factors that influence food acceptance were assessed. RESULTS: The total weight of 1,877 meals was 868kg and the weight of the leftovers was 313kg, thus a leftover-ingestion index of 36.09%. The percentage of leftovers of the special diets with salt, normal diets and special diets without salt were 53.68%, 33.99% and 33.84%, respectively. The patients were satisfied with the variety, amount and presentation of the meals but complained about the temperature and seasonings, with ratings of 43.00% and 34.30%, respectively. The leftover-ingestion index (36.09%) was above the acceptable index (20.00%) for a diseased population, indicating a considerable waste of food. CONCLUSION: The results show that it is necessary to assess the meal production processes and develop strategies that encourage the patients to eat