43 research outputs found
Active PSF shaping and adaptive optics enable volumetric localization microscopy through brain sections
Get PDFApplication of single-molecule switching nanoscopy (SMSN) beyond the coverslip surface poses substantial challenges due to sample-induced aberrations that distort and blur single-molecule emission patterns. We combined active shaping of point spread functions and efficient adaptive optics to enable robust 3D-SMSN imaging within tissues. This development allowed us to image through 30-μm-thick brain sections to visualize and reconstruct the morphology and the nanoscale details of amyloid-β filaments in a mouse model of Alzheimer's disease
A gait skeleton model extraction method based on the fusion between vision and tactility
No full textSuper-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics
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Super-resolution Microscopical Localization of Dopamine Receptors 1 and 2 in Rat Hippocampal Synaptosomes
No full textIs the breast-conserving treatment with radiotherapy appropriate in BRCA1/2 mutation carriers? Long-term results and review of the literature
No full textKaleido: Visualizing Big Brain Data with Automatic Color Assignment for Single-Neuron Images
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Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis
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