Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

The mesenchymal stroma harbors an important population of cells that possess stem cell-like characteristics including self renewal and differentiation capacities and can be derived from a variety of different sources. These multipotent mesenchymal stem cells (MSC) can be found in nearly all tissues and are mostly located in perivascular niches. MSC have migratory abilities and can secrete protective factors and act as a primary matrix for tissue regeneration during inflammation, tissue injuries and certain cancers

H-MODE THRESHOLD AND DYNAMICS IN THE NATIONAL SPHERICAL TORUS EXPERIMENT

Edge parameters play a critical role in high confinement mode (H-mode) access, which is a key component of discharge optimization in present day toroidal confinement experiments and the design of next generation devices. Because the edge magnetic topology of a spherical torus (ST) differs from a conventional aspect ratio tokamak, H-modes in STs exhibit important differences compared with tokamaks. The dependence of the National Spherical Torus Experiment (NSTX) [C. Neumeyer , Fusion Eng. Des. 54, 275 (2001)] edge plasma on heating power, including the low confinement mode (L-mode) to H-mode (L-H) transition requirements and the occurrence of edge-localized modes (ELMs), and on divertor configuration is quantified. Comparisons between good L-modes and H-modes show greater differences in the ion channel than the electron channel. The threshold power for the H-mode transition in NSTX is generally above the predictions of a recent International Tokamak Experimental Reactor (ITER) [ITER Physics Basis Editors, Nucl. Fusion 39, 2175 (1999)] scaling. Correlations of transition and ELM phenomena with turbulent fluctuations revealed by gas puff imaging and reflectometry are observed. In both single-null and double-null divertor discharges, the density peaks off-axis, sometimes developing prominent "ears" which can be sustained for many energy confinement times, tau(E), in the absence of ELMs. A wide variety of ELM behavior is observed, and ELM characteristics depend on configuration and fueling. (C) 2003 American Institute of Physics.open112324sciescopu

Progress towards high-performance, steady-state spherical torus

Research on the spherical torus (or spherical tokamak) (ST) is being pursued to explore the scientific benefits of modifying the field line structue fro that in more moderate aspect ratio devices. The ST experiments are being conducted in various US research facilities. The area of power and particle handling is expected to be challenging because of the higher power density expected in the ST relative to that in conventional aspect-ratio tokamaks

The national spherical torus experiment (NSTX) research programme and progress towards high beta, long pulse operating scenarios

A major research goal of the national spherical torus experiment is establishing long-pulse, high beta, high confinement operation and its physics basis. This research has been enabled by facility capabilities developed during 2001 and 2002, including neutral beam (up to 7 MW) and high harmonic fast wave (HHFW) heating (up to 6 MW), toroidal fields up to 6 kG, plasma currents up to 1.5 MA, flexible shape control, and wall preparation techniques. These capabilities have enabled the generation of plasmas with β ≡ /(B /2μ ) of up to 35%. Normalized beta values often exceed the no-wall limit, and studies suggest that passive wall mode stabilization enables this for H mode plasmas with broad pressure profiles. The viability of long, high bootstrap current fraction operations has been established for ELMing H mode plasmas with toroidal beta values in excess of 15% and sustained for several current relaxation times. Improvements in wall conditioning and fuelling are likely contributing to a reduction in H mode power thresholds. Electron thermal conduction is the dominant thermal loss channel is auxiliary heated plasmas examined thus far. HHFW effectively heats electrons, and its acceleration of fast beam ions has been observed. Evidence for HHFW current drive is obtained by comparison of the loop voltage evolution in plasmas with matched density and temperature profiles but varying phases of launched HHFW waves. Studies of emissions from electron Bernstein waves indicate a density scale length dependence of their transmission across the upper hybrid resonance near the plasma edge that is consistent with theoretical predictions. A peak heat flux to the divertor targets of 10 MW m has been measured in the H mode, with large asymmetries being observed in the power deposition between the inner and outer strike points. Non-inductive plasma startup studies have focused on coaxial helicity injection. With this technique, toroidal currents up to 400 kA have been driven, and studies to assess flux closure and coupling to other current drive techniques have begun. T T0 0 2 -

Progress towards high-performance, steady-state spherical torus

Research on the spherical torus (or spherical tokamak) (ST) is being pursued to explore the scientific benefits of modifying the field line structue fro that in more moderate aspect ratio devices. The ST experiments are being conducted in various US research facilities. The area of power and particle handling is expected to be challenging because of the higher power density expected in the ST relative to that in conventional aspect-ratio tokamaks

The national spherical torus experiment (NSTX) research programme and progress towards high beta, long pulse operating scenarios

A major research goal of the national spherical torus experiment is establishing long-pulse, high beta, high confinement operation and its physics basis. This research has been enabled by facility capabilities developed during 2001 and 2002, including neutral beam (up to 7 MW) and high harmonic fast wave (HHFW) heating (up to 6 MW), toroidal fields up to 6 kG, plasma currents up to 1.5 MA, flexible shape control, and wall preparation techniques. These capabilities have enabled the generation of plasmas with βT ≡ /(BT02/2μ0) of up to 35%. Normalized beta values often exceed the no-wall limit, and studies suggest that passive wall mode stabilization enables this for H mode plasmas with broad pressure profiles. The viability of long, high bootstrap current fraction operations has been established for ELMing H mode plasmas with toroidal beta values in excess of 15% and sustained for several current relaxation times. Improvements in wall conditioning and fuelling are likely contributing to a reduction in H mode power thresholds. Electron thermal conduction is the dominant thermal loss channel is auxiliary heated plasmas examined thus far. HHFW effectively heats electrons, and its acceleration of fast beam ions has been observed. Evidence for HHFW current drive is obtained by comparison of the loop voltage evolution in plasmas with matched density and temperature profiles but varying phases of launched HHFW waves. Studies of emissions from electron Bernstein waves indicate a density scale length dependence of their transmission across the upper hybrid resonance near the plasma edge that is consistent with theoretical predictions. A peak heat flux to the divertor targets of 10 MW m-2 has been measured in the H mode, with large asymmetries being observed in the power deposition between the inner and outer strike points. Non-inductive plasma startup studies have focused on coaxial helicity injection. With this technique, toroidal currents up to 400 kA have been driven, and studies to assess flux closure and coupling to other current drive techniques have begun