2,999 research outputs found

    PCN25 COST-EFFECTIVENESS ANALYSIS OF ERLOTINIB VERSUS DOCETAXEL AS A SECOND- OR THIRD-LINE TREATMENT OF NON-SMALL CELL LUNG CANCER IN KOREA

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    Hybrid desalination processes for beneficial use of reverse osmosis brine: Current status and future prospects

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    © 2018 Elsevier B.V. As water shortage has increasingly become a serious global problem, desalination using seawater reverse osmosis (SWRO) is considered as a sustainable source of potable water sources. However, a major issue on the SWRO desalination plant is the generation of brine that has potential adverse impact due to its high salt concentration. Accordingly, it is necessary to develop technologies that allow environmentally friendly and economically viable management of SWRO brines. This paper gives an overview of recent research works and technologies to treat SWRO brines for its beneficial use. The treatment processes have been classified into two different groups according to their final purpose: 1) technologies for producing fresh water and 2) technologies for recovering energy. Topics in this paper includes membrane distillation (MD), forward osmosis (FO), pressure-retarded osmosis (PRO), reverse electrodialysis (RED) as emerging tools for beneficial use of SWRO brine. In addition, a new approach to simultaneously recover water and energy from SWRO brine is introduced as a case study to provide insight into improving the sustainability of seawater desalination

    Chasing Carbon: The Elusive Environmental Footprint of Computing

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    Given recent algorithm, software, and hardware innovation, computing has enabled a plethora of new applications. As computing becomes increasingly ubiquitous, however, so does its environmental impact. This paper brings the issue to the attention of computer-systems researchers. Our analysis, built on industry-reported characterization, quantifies the environmental effects of computing in terms of carbon emissions. Broadly, carbon emissions have two sources: operational energy consumption, and hardware manufacturing and infrastructure. Although carbon emissions from the former are decreasing thanks to algorithmic, software, and hardware innovations that boost performance and power efficiency, the overall carbon footprint of computer systems continues to grow. This work quantifies the carbon output of computer systems to show that most emissions related to modern mobile and data-center equipment come from hardware manufacturing and infrastructure. We therefore outline future directions for minimizing the environmental impact of computing systems

    Novel membrane bioreactor (MBR) coupled with a nonwoven fabric filter for household wastewater treatment

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    Conventional and modified membrane bioreactors (MBRs) are increasingly used in small-scale wastewater treatment. However, their widespread applications are hindered by their relatively high cost and operational complexity. In this study, we investigate a new concept of wastewater treatment using a nonwoven fabric filter bag (NFFB) as the membrane bioreactor. Activated sludge is charged in the nonwoven fabric filter bag and membrane filtration via the fabric is achieved under gravity flow without a suction pump. This study found that the biofilm layer formed inside the NFFB achieved 10 mg/L of suspended solids in the permeate within 20 min of initial operation. The dynamic biofilter layer showed good filterability and the specific membrane resistance consisted of 0.3-1.9 × 1012 m/kg. Due to the low F/M ratio (0.04-0.10 kg BOD5/m3/d) and the resultant low sludge yield, the reactor was operated without forming excess sludge. Although the reactor provided aerobic conditions, denitrification occurred in the biofilm layer to recover the alkalinity, thereby eliminating the need to supplement the alkalinity. This study indicates that the NFFB system provides a high potential of effective wastewater treatment with simple operation at reduced cost, and hence offer an attractive solution for widespread use in rural and sparsely populated areas. Crown Copyright © 2009

    Just diverse among themselves: how does negative performance feedback affect boards' expertise vs. ascriptive diversity?

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    We investigate how negative performance feedback affects board diversity, which is instrumental in shaping a firm’s strategic change. When a firm underperforms compared with its aspiration, its board is motivated to promptly address the underperformance. The board needs to not only help search for strategic alternatives but also quickly build consensus around its strategic reorientation. These two motivations lead the board to value two dimensions of diversity among its members differently. On the one hand, to understand the problem of underperformance and find a solution, the board is motivated to seek new expertise, avoiding redundancy in the pool of expertise already represented in the boardroom. This results in a higher level of diversity in director expertise. On the other hand, the urgent need to build consensus prompts the board to value trust and solidarity and to avoid potential conflict among directors. Because people perceive others with similar ascriptive backgrounds as trustworthy, changes in the board of an underperforming firm are likely to yield a lower level of diversity in its members’ ascriptive backgrounds. These changes in board are affected by the committee chairs of the board whose power and influence are significant in the boardroom. Analyses of the boards of 733 U.S. listed manufacturing firms show that when a firm underperforms compared with its aspirations, it increases the board expertise diversity, but decreases the board ascriptive diversity. When chairs on the board are gender or racial minorities, the negative association between underperformance and the board ascriptive diversity is weakened

    High-performance triazole-containing brush polymers via azide-alkyne click chemistry: a new functional polymer platform for electrical memory devices

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    Two series of well-defined brush polymers bearing a triazole moiety on each bristle were prepared from the click chemistry reactions of a poly(glycidyl azide) (PG) and a poly(4-azidomethylstyrene) (PS) with alkyne derivatives. The thin-film morphologies and properties, especially electrical memory performances, of these triazole-containing brush polymers were investigated in detail. The brush polymers with a triazole ring substituted with an alkyl or alkylenylphenyl group in the bristle exhibited only dielectric characteristics. By contrast, the other brush polymers bearing a triazole ring substituted with phenyl or its derivatives with a longer pi-conjugation length in the bristle demonstrated excellent unipolar permanent memory behaviors with low power consumption, high ON/OFF current ratios and high stability and reliability under ambient air conditions. Furthermore, their memory type could be tuned to p- or n-type by the incorporation of an electron-donating or -accepting group into the phenyl unit linked to the triazole moiety. Overall, this study presents the first demonstration of the azide-alkyne click chemistry synthesis of triazole moieties with substituent(s) that exhibit a resonance effect; this approach is a very powerful synthetic route to develop electrical memory polymers suitable for the low-cost mass production of high-performance, polarity-free programmable memory devices.111711Ysciescopu

    CMS endcap RPC gas gap production for upgrade

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    The CMS experiment will install a RE4 layer of 144 new Resistive Plate Chambers (RPCs) on the existing york YE3 at both endcap regions to trigger high momentum muons from the proton-proton interaction. In this paper, we present the detailed procedures used in the production of new RPC gas gaps adopted in the CMS upgrade. Quality assurance is enforced as ways to maintain the same quality of RPC gas gaps as the existing 432 endcap RPC chambers that have been operational since the beginning of the LHC operation

    High Fidelity Tape Transfer Printing Based On Chemically Induced Adhesive Strength Modulation

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    Transfer printing, a two-step process (i.e. picking up and printing) for heterogeneous integration, has been widely exploited for the fabrication of functional electronics system. To ensure a reliable process, strong adhesion for picking up and weak or no adhesion for printing are required. However, it is challenging to meet the requirements of switchable stamp adhesion. Here we introduce a simple, high fidelity process, namely tape transfer printing(TTP), enabled by chemically induced dramatic modulation in tape adhesive strength. We describe the working mechanism of the adhesion modulation that governs this process and demonstrate the method by high fidelity tape transfer printing several types of materials and devices, including Si pellets arrays, photodetector arrays, and electromyography (EMG) sensors, from their preparation substrates to various alien substrates. High fidelity tape transfer printing of components onto curvilinear surfaces is also illustrated

    A possible method for non-Hermitian and non-PTPT-symmetric Hamiltonian systems

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    A possible method to investigate non-Hermitian Hamiltonians is suggested through finding a Hermitian operator η+\eta_+ and defining the annihilation and creation operators to be η+\eta_+-pseudo-Hermitian adjoint to each other. The operator η+\eta_+ represents the η+\eta_+-pseudo-Hermiticity of Hamiltonians. As an example, a non-Hermitian and non-PTPT-symmetric Hamiltonian with imaginary linear coordinate and linear momentum terms is constructed and analyzed in detail. The operator η+\eta_+ is found, based on which, a real spectrum and a positive-definite inner product, together with the probability explanation of wave functions, the orthogonality of eigenstates, and the unitarity of time evolution, are obtained for the non-Hermitian and non-PTPT-symmetric Hamiltonian. Moreover, this Hamiltonian turns out to be coupled when it is extended to the canonical noncommutative space with noncommutative spatial coordinate operators and noncommutative momentum operators as well. Our method is applicable to the coupled Hamiltonian. Then the first and second order noncommutative corrections of energy levels are calculated, and in particular the reality of energy spectra, the positive-definiteness of inner products, and the related properties (the probability explanation of wave functions, the orthogonality of eigenstates, and the unitarity of time evolution) are found not to be altered by the noncommutativity.Comment: 15 pages, no figures; v2: clarifications added; v3: 16 pages, 1 figure, clarifications made clearer; v4: 19 pages, the main context is completely rewritten; v5: 25 pages, title slightly changed, clarifications added, the final version to appear in PLOS ON
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