Akut lenfoplastik lösemili çocuklarda çeşitli lenfosit yüzey işaretleri ve interleukin-2 seviyeleri

TEZ2927Tez (Uzmanlık) -- Çukurova Üniversitesi, Adana, 1997.Kaynakça (s. 38-43) var.43 s. ; 30 cm.

Exploring Knowledge Workers in the Turkish Construction Sector

This research focuses on evaluating the potential of architects/engineers as Knowledge Workers (KW) operating in the Turkish construction sector. A survey to identify the presence of KWs was prepared and applied to 113 of 324 employees, including architects and engineers from 138 different large-scale Turkish contractor companies (head offices, design offices, technical offices and construction sites). The survey consists of two main sections that (1) recognise the profile of the participants and companies and (2) six sub-sections as communication, motivation, autonomy, possessing theoretical and practical knowledge, ability to access and use information, and intellectual ability. The results of the survey indicate that architects have a higher potential to be identified as KWs than engineers in the Turkish construction sector. Furthermore, the number of KWs among the design and head office workers is higher, because there are a higher number of architects working in these departments.The potential of being a KW increases in parallel to the level of education of the employees, which is determined from a Bachelor's degree and PhD degree. When examining gender statistics in the survey, women employees have higher scores than men. The findings of this study should guide the construction sector professionals in Turkey as well as those from other countries who seek to identify the KWs in the contractor companies. This research, with the approach and methodology, may provide better management of human resources by identifying and placing these valuable employees correctly

Retrospective Evaluation of Distribution and Antifungal Susceptibilities of Candida Species Isolated from Blood Cultures

Kandidemi yüksek mortalite ile seyreden ciddi bir klinik tablodur. Son yıllarda Candida infeksiyonlarının epidemiyolojisi ve tedavide kullanılan antifungallerle ilgili önemli değişiklikler ortaya çıkmıştır. Bu çalışmada kan kültürlerinden izole edilen Candida türlerinin tanımlanması ve bunların amfoterisin B, kaspofungin, flukonazol, flusitozin ve vorikonazole duyarlılıklarının retrospektif olarak araştırılması amaçlanmıştır.Laboratuvarımıza Ocak 2013-Aralık 2014 döneminde gönderilen kan kültürlerinde tespit edilen maya üremeleri konvansiyonel yöntemler, germ tüp ve VITEK 2 Compact (bioMérieux, Fransa) otomatize identifikasyon sistemi ile tiplendirilmiş ve antifungal duyarlılıkları VITEK 2 Compact sistemi ile belirlenmiştir.İzole edilen 280 Candida suşunun 95'i (% 33.9) Candida parapsilosis, 77'si (% 27.5) Candida albicans, 45'i (% 16) Candida tropicalis, 27'si (% 9.6) Candida glabrata, dokuzar tanesi (% 3.2) Candida kefyr ve Candida lusitaniae, beşi (% 1.7) Candida krusei, dörder tanesi (% 1.4) Candida famata ve Candida sphaerica, ikisi (% 0.7) Candida dubliniensis, birer tanesi de (% 0.3) Candida haemulonii, Candida norvegensis ve Candida pelliculosa olarak tanımlanmıştır. Antifungal duyarlılık yorumlamaları C.albicans, C.parapsilosis, C.tropicalis, C.glabrata, C.krusei olarak izole edilen 249 izolat için yapılmıştır. Antifungallere dirençli Candida türlerinin saptandığı çalışmamızda, üreme saptanan kan kültürlerindeki Candida türlerinin tanımlanmasının ve antifungal duyarlılıklarının bildirilmesinin, tedaviyi yönlendirmek için önemli olduğu sonucuna varılmıştırCandidemia is a serious clinical presentation with a rather high mortality. Over the last years, there have been important changes in the epidemiology of Candida infections and antifungal agents used to treat these infections. In this study, the identification of the Candida species isolated from blood cultures and investigation of their susceptibilities against amphotericin B, caspofungin, fluconazole, flucytosine and voriconazole retrospectively were aimed. Yeasts detected from blood cultures in our laboratory between January 2013 and December 2014 were identified by conventional methods, germ tube and VITEK 2 Compact (bioMérieux, France) automated identification system and susceptibilities to antifungal agents were determined by VITEK 2 Compact System. Among 280 Candida spp., strains isolated, 95 (33.9 %) were identified as Candida parapsilosis, the others were identified as follows: 77 (27.5 %) Candida albicans, 45 (16 %) Candida tropicalis, 27(9.6 %) Candida glabrata, nine (3.2 %) Candida kefyr, nine (3.2 %) Candida lusitaniae, five (1.7 %) Candida krusei, four (1.4 %) Candida famata, four (1.4 %) Candida sphaerica, two (0.7 %) Candida dubliniensis, one (0.3 %) Candida haemulonii, one (0.3 %) Candida norvegensis and one (0.3 %) Candida pelliculosa. Interpretation of antifungal susceptibility tests of C.albicans, C.parapsilosis, C.tropicalis, C.glabrata, C.krusei isolates were made to 249 as described. As a result of our study, in which Candida strains resistant to antifungal agents were isolated, identification to species level and determining antifungal susceptibilities of Candida species isolated from blood cultures is concluded to be important to guide treatment

The role of various nursing activities on coliform contamination of hands

Çukurova Üniversitesi Balcalı Hastanesi'nde Yenidoğan ve Pediyatrik Hematoloji-Onkoloji Üniteleri'nde çalışan hemşirelerin ve hastaların ellerinden koliform bakterileri izole edildi. Hemşire ellerinin hangi aktivasyonlardan sonra koliformlarla kontamine olduğunu göstermek için EMB (Eozin Metilen Blue) ağara alınan parmak izleri incelendi. Koliformlar en sık olarak, hemşirelerin hastaların kirli giysilerine, hastalara veya onların elbiselerine temaslarından sonra ve hastalara ait kullanılmış tıbbi malzemelere dokunulduktan sonra üretildi. Pediyatrik Hematoloji-Onkoloji Servisi'ndeki hastalardan alınan parmak izi kültürlerinin dörtte birinden fazlasında koliformların ürediği saptandı.Coliform bacilli were recovered from the hands of nurses and patients in the Newborn and Pédiatrie Hematology-Oncology Units in Çukurova University, Balcalı Hospital. The types of nursing activities that led to hand contamination by conforms were analyzed by sampling fingerpad imprints on EMB (Eosin-Methylen-Blue) agar. Conforms were frequently recovered from nurses' hands after touching patients' dirty clothes, patients or their clothes as well as handling their dirty linen. Conforms were also recovered from the finger prints of more than one fourth of the patients in the Pédiatrie Hematology-Oncology Unit

Bir telsiz duyarga ağı sınama ortamının MSP430G2553 ve nRF24L01+ tabanlı duyargalar ile geliştirilmesi

Bir telsiz duyarga ağında (TDA) hedeflenen uygulamanın başarı ile gerçekleştirilmesinin yanı sıra, duyarga başına harcanan toplam enerji gibi sistem kaynaklarının etkili kullanılması gerekmektedir. İncelenen sahada farklı uygulamalar için çok sayıda duyargaya ihtiyaç duyulabileceğinden, tüm sistemin maliyet etkin olabilmesi için her bir duyarganın da düşük masrafla üretilmesi de önemlidir. Bu makalede, öncelikle özel yapılmış, az enerji tüketen ve maliyeti düşük olan, MSP430G2553 mikroişlemcisi ve nRf24l01+ haberleşme ünitesi tabanlı bir duyarganın geliştirilmesi amaçlanmıştır. Sonrasında geliştirilen bu duyargalar kullanılarak sade bir TDA sınama ortamı oluşturulmuş ve ışık kaynağının konum tespiti çalışması yapılmıştır

Evaluation of the Antibiotic Resistance Profiles of Enterococcus Species Isolated from Urine Cultures

Amaç: Enterokoklarda son yıllarda antimikrobik ajanlara karşı artan oranda direnç gözlenmektedir. Bu çalışmanın amacı, hastanemizde yatarak tedavi gören hastaların idrar kültürlerinden izole edilen enterokok türlerini ve antibiyotik direnç oranlarını belirlemektir.Gereç ve Yöntem: Bu çalışmada Çukurova Üniversitesi Tıp Fakültesi Balcalı Hastanesi'nde yatarak tedavi edilen hastaların Ocak 2012-Nisan 2014 arasında idrar örneklerinden izole edilen, toplam 536 enterokok suşunun tiplendirilmesi yapılarak, çeşitli antibiyotiklere direnç oranları belirlenmiştir. Enterokok suşlarının identifikasyonu ve antimikrobiyal duyarlılıkları otomatik Vitek-2 sistemi (BioMérieux, Fransa) ile yapılmıştır.Bulgular: İzole dilen suşların 277 (%51.6)'si Enterococcus faecalis, 249 (%46.4)'u Enterococcus faecium, 5 (% 0.9)'i Enterococcus avium, 2 (%0.3)'si Enterococcus durans, 2 (%0.3)'si Enterococcus gallinarum, 1 (%0.1)'i Enterococcus hirae olarak tanımlanmıştır. Trimetoprim/sulfametoksazol'e %98.1, klindamisine %97, ampisiline %84.2, eritromisine %83.2, imipeneme %83.2, tetrasikline %73.3, siprofloksasine %66.6, moksifloksasine %65.1, vankomisine %14.7, teikoplanine %14.3, linezolide %4.8 ve tigesikline %0.3 oranında direnç gözlenmiştir. Yüksek düzey aminoglikozit direnci yalnızca gentamisin için %9.3, yalnızca streptomisin için %17.5 olarak belirlenmiştir.Sonuç: Bu çalışmada, glikopeptit dirençli enterokok suşları saptanmıştır. Hastanemizde saptanan vankomisin ve teikoplanin direnci, bu antibiyotiklerin enterokok enfeksiyonlarında dikkatli kullanılmasının gerektiğini göstermektedir.Objective: In recent years, enterococci have become increasingly resistant to a wide range of antimicrobial agents. The aim of this study was to identify the species isolated from the urine cultures of hospitalized patients at Cukurova University Medical Faculty Balcalı Hospital, Adana, Turkey. and determine antimicrobial susceptibility rates of enterococcus strains.Materials and Methods: In this study, a total of 536 enterococcus strains isolated from the urine cultures of the patients hospitalized, and treated in Balcalı Hospital of Çukurova University Faculty of Medicine between January 2012 and April 2014 were typed and antibiotic resistance rates of these isolated were determined Identification and antibiotic susceptibility testing of the enterococci strains were performed using Vitek-2 automated system (BioMérieux, France).Results: Of these isolated strains 277 (51.6%) were identified as Enterococcus faecalis, 249 (46.4%) as Enterococcus faecium, five (0.9%) as Enterococcus avium, two (0.3%) as Enterococcus durans, two (0.3%) as Enterococcus gallinarum and one (0.1%) as Enterococcus hirae. The rates of resistance were 98.1% to trimethoprim/sulfamethoxazole, 97% to clindamycin, 84.2% to ampicillin, 83.2% to erythromycin, 83.2% to imipenem, 73.3% to tetracycline, 66.6% to ciprofloxacin, 65.1% to moxifloxacin, 14.7% to vancomycin, 14.3% to teicoplanin, 4.8% to linezolid and 0.3% to tigecycline. High level aminoglycoside resistance was detected as 9.3 % for only gentamicin and 17.5% for only streptomycin.Conclusion: In this study, glycopeptide resistant enterococcus strains were detected. Thus,resistance to vancomycin and teicoplanin detected in our hospital demonstrates that these antibioticst should be used cautiously in the treatment of enterococcal infections in our center

Molecular characterization of methicillin-resistant Staphylococcus aureus strains by spa typing and pulsed field gel electrophoresis methods

Abstract Background Rapid detection of sources and transmission routes by molecular methods provides key data for risk management of methicillin-resistant Staphylococcus aureus-induced infections acquired in both the community and hospitals. This study aimed to determine the clonal relationship of methicillin-resistant S. aureus strains isolated from our hospital by pulsed-field gel electrophoresis (PFGE) and Staphylococcal protein A (spa) typing methods and to identify the predominant clones in Cukurova Region, Turkey. Results All isolates analyzed by PFGE were distributed among 11 clusters. Clusters A (n = 19) and B (n = 27) were 84.1% similar and accounted for 61% of all samples. All isolates were distributed among 18 spa types, with the most common type being t030 with 31 isolates (41.3%), followed by t223 with nine isolates (12%) and t127 with seven isolates (9.3%). Conclusions We found that t030 was the most common spa type in the area where the study was conducted, as also previously shown in studies undertaken in Turkey. However, the rate of t030 in our study was below the rates reported in the literature. We also detected some rare or sporadic spa types like t127, which has not been previously defined in our country. We consider that the spa typing and PFGE methods are useful for research on clonal relations in monitoring the changing prevalent clones in specific regions