Crumpling wires in two dimensions

An energy-minimal simulation is proposed to study the patterns and mechanical properties of elastically crumpled wires in two dimensions. We varied the bending rigidity and stretching modulus to measure the energy allocation, size-mass exponent, and the stiffness exponent. The mass exponent is shown to be universal at value $D_{M}=1.33$. We also found that the stiffness exponent $\alpha =-0.25$ is universal, but varies with the plasticity parameters $s$ and $\theta_{p}$. These numerical findings agree excellently with the experimental results

Response-surface-model-based system sizing for nearly/net zero energy buildings under uncertainty

Properly treating uncertainty is critical for robust system sizing of nearly/net zero energy buildings (ZEBs). To treat uncertainty, the conventional method conducts Monte Carlo simulations for thousands of possible design options, which inevitably leads to computation load that is heavy or even impossible to handle. In order to reduce the number of Monte Carlo simulations, this study proposes a response-surface-model-based system sizing method. The response surface models of design criteria (i.e., the annual energy match ratio, self-consumption ratio and initial investment) are established based on Monte Carlo simulations for 29 specific design points which are determined by Box-Behnken design. With the response surface models, the overall performances (i.e., the weighted performance of the design criteria) of all design options (i.e., sizing combinations of photovoltaic, wind turbine and electric storage) are evaluated, and the design option with the maximal overall performance is finally selected. Cases studies with 1331 design options have validated the proposed method for 10,000 randomly produced decision scenarios (i.e., users’ preferences to the design criteria). The results show that the established response surface models reasonably predict the design criteria with errors no greater than 3.5% at a cumulative probability of 95%. The proposed method reduces the number of Monte Carlos simulations by 97.8%, and robustly sorts out top 1.1% design options in expectation. With the largely reduced Monte Carlo simulations and high overall performance of the selected design option, the proposed method provides a practical and efficient means for system sizing of nearly/net ZEBs under uncertainty

DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration.

Deleted in liver cancer 1 (DLC1) is a RhoGTPase activation protein-containing tumor suppressor that associates with various types of cancer. Although DLC2 shares a similar domain structure with that of DLC1, the function of DLC2 is not well characterized. Here, we describe the expression and ablation of DLC2 in mice using a reporter-knockout approach. DLC2 is expressed in several tissues and in endothelial cells (ECs) of blood vessels. Although ECs and blood vessels show no histological abnormalities and mice appear overall healthy, DLC2-mutant mice display enhanced angiogenic responses induced by matrigel and by tumor cells. Silencing of DLC2 in human ECs has reduced cell attachment, increased migration, and tube formation. These changes are rescued by silencing of RhoA, suggesting that the process is RhoA pathway dependent. These results indicate that DLC2 is not required for mouse development and normal vessel formation, but may protect mouse from unwanted angiogenesis induced by, for example, tumor cells

Formation time distribution of dark matter haloes: theories versus N-body simulations

This paper uses numerical simulations to test the formation time distribution of dark matter haloes predicted by the analytic excursion set approaches. The formation time distribution is closely linked to the conditional mass function and this test is therefore an indirect probe of this distribution. The excursion set models tested are the extended Press-Schechter (EPS) model, the ellipsoidal collapse (EC) model, and the non-spherical collapse boundary (NCB) model. Three sets of simulations (6 realizations) have been used to investigate the halo formation time distribution for halo masses ranging from dwarf-galaxy like haloes ($M=10^{-3} M_*$, where $M_*$ is the characteristic non-linear mass scale) to massive haloes of $M=8.7 M_*$. None of the models can match the simulation results at both high and low redshift. In particular, dark matter haloes formed generally earlier in our simulations than predicted by the EPS model. This discrepancy might help explain why semi-analytic models of galaxy formation, based on EPS merger trees, under-predict the number of high redshift galaxies compared with recent observations.Comment: 7 pages, 5 figures, accepted for publication in MNRA

Nonuniversal Effects in the Homogeneous Bose Gas

Effective field theory predicts that the leading nonuniversal effects in the homogeneous Bose gas arise from the effective range for S-wave scattering and from an effective three-body contact interaction. We calculate the leading nonuniversal contributions to the energy density and condensate fraction and compare the predictions with results from diffusion Monte Carlo calculations by Giorgini, Boronat, and Casulleras. We give a crude determination of the strength of the three-body contact interaction for various model potentials. Accurate determinations could be obtained from diffusion Monte Carlo calculations of the energy density with higher statistics.Comment: 24 pages, RevTex, 5 ps figures, included with epsf.te