A multi-view approach to cDNA micro-array analysis

The official published version can be obtained from the link below.Microarray has emerged as a powerful technology that enables biologists to study thousands of genes simultaneously, therefore, to obtain a better understanding of the gene interaction and regulation mechanisms. This paper is concerned with improving the processes involved in the analysis of microarray image data. The main focus is to clarify an image's feature space in an unsupervised manner. In this paper, the Image Transformation Engine (ITE), combined with different filters, is investigated. The proposed methods are applied to a set of real-world cDNA images. The MatCNN toolbox is used during the segmentation process. Quantitative comparisons between different filters are carried out. It is shown that the CLD filter is the best one to be applied with the ITE.This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) of the UK under Grant GR/S27658/01, the National Science Foundation of China under Innovative Grant 70621001, Chinese Academy of Sciences under Innovative Group Overseas Partnership Grant, the BHP Billiton Cooperation of Australia Grant, the International Science and Technology Cooperation Project of China under Grant 2009DFA32050 and the Alexander von Humboldt Foundation of Germany

Suspension performance with one damper and one inerter

In Chen & Smith 2009, a class of realizations in which the number of dampers and inerters is restricted to one in each case, while allowing an arbitrary number of springs (which is the easiest element to realize practically), was considered and it was proven that at most four springs are needed-an explicit construction was given comprising five different circuit arrangements to cover all cases. This paper makes a comparative study of the performances of these five circuit arrangements when applied as mechanical suspension struts in a quarter-car model.published_or_final_versio

Charmless two-body B decays: A global analysis with QCD factorization

In this paper, we perform a global analysis of $B \to PP$ and $PV$ decays with the QCD factorization approach. It is encouraging to observe that the predictions of QCD factorization are in good agreement with experiment. The best fit $\gamma$ is around $79^\circ$. The penguin-to-tree ratio $|P_{\pi \pi}/T_{\pi \pi}|$ of $\pi^+ \pi^-$ decays is preferred to be larger than 0.3. We also show the confidence levels for some interesting channels: $B^0 \to \pi^0 \pi^0$, $K^+ K^-$ and $B^+ \to \omega \pi^+$, $\omega K^+$. For $B \to \pi K^\ast$ decays, they are expected to have smaller branching ratios with more precise measurements.Comment: 20 pages, 4 figures, version to appear in Phys. Rev.

Density of states and Fisher's zeros in compact U(1) pure gauge theory

We present high-accuracy calculations of the density of states using multicanonical methods for lattice gauge theory with a compact gauge group U(1) on 4^4, 6^4 and 8^4 lattices. We show that the results are consistent with weak and strong coupling expansions. We present methods based on Chebyshev interpolations and Cauchy theorem to find the (Fisher's) zeros of the partition function in the complex beta=1/g^2 plane. The results are consistent with reweighting methods whenever the latter are accurate. We discuss the volume dependence of the imaginary part of the Fisher's zeros, the width and depth of the plaquette distribution at the value of beta where the two peaks have equal height. We discuss strategies to discriminate between first and second order transitions and explore them with data at larger volume but lower statistics. Higher statistics and even larger lattices are necessary to draw strong conclusions regarding the order of the transition.Comment: 14 pages, 16 figure

Double-peaked Narrow Emission-line Galaxies in LAMOST Survey

We outline a full-scale search for galaxies exhibiting double-peaked profiles of promi- nent narrow emission lines, motivated by the prospect of finding objects related to merging galaxies, and even dual active galactic nuclei candidates as by-product, from the Large Sky Area Multi-object Fiber Spectroscopic Telescope (LAMOST) Data Re- lease 4. We assemble a large sample of 325 candidates with double-peaked or strong asymmetric narrow emission lines, with 33 objects therein appearing optically resolved dual-cored structures, close companions or signs of recent interaction on the Sloan Dig- ital Sky Survey images. A candidate from LAMOST (J074810.95+281349.2) is also stressed here based on the kinematic and spatial decompositions of the double-peaked narrow emission line target, with analysis from the cross-referenced Mapping Nearby Galaxies at the Apache Point Observatory (MaNGA) survey datacube. MaNGA en- ables us to constrain the origin of double peaks for these sources, and with the IFU data we infer that the most promising origin of double-peaked profiles for LAMOST J074810.95+281349.2 is the `Rotation Dominated + Disturbance' structure.Comment: 13 pages, 9 figures, accepted by MNRA

Very Long Baseline Interferometry Measured Proper Motion and Parallax of the γ\gamma-ray Millisecond Pulsar PSR J0218+4232

PSR J0218$+$4232 is a millisecond pulsar (MSP) with a flux density $\sim$ 0.9 mJy at 1.4 GHz. It is very bright in the high-energy X-ray and $\gamma$-ray domains. We conducted an astrometric program using the European VLBI Network (EVN) at 1.6 GHz to measure its proper motion and parallax. A model-independent distance would also help constrain its $\gamma$-ray luminosity. We achieved a detection of signal-to-noise ratio S/N > 37 for the weak pulsar in all five epochs. Using an extragalactic radio source lying 20 arcmin away from the pulsar, we estimate the pulsar's proper motion to be $\mu_{\alpha}\cos\delta=5.35\pm0.05$ mas yr$^{-1}$ and $\mu_{\delta}=-3.74\pm 0.12$ mas yr$^{-1}$, and a parallax of $\pi=0.16\pm0.09$ mas. The very long baseline interferometry (VLBI) proper motion has significantly improved upon the estimates from long-term pulsar timing observations. The VLBI parallax provides the first model-independent distance constraints: $d=6.3^{+8.0}_{-2.3}$ kpc, with a corresponding $3\sigma$ lower-limit of $d=2.3$ kpc. This is the first pulsar trigonometric parallax measurement based solely on EVN observations. Using the derived distance, we believe that PSR J0218$+$4232 is the most energetic $\gamma$-ray MSP known to date. The luminosity based on even our 3$\sigma$ lower-limit distance is high enough to pose challenges to the conventional outer gap and slot gap models.Comment: 5 pages, 2 figures, 2 tables; published in the Astrophysical Journal Letters on 2014 Feb. 1

Stability and stabilization of delayed T-S fuzzy systems: A delay partitioning approach

This paper proposes a new approach, namely, the delay partitioning approach, to solving the problems of stability analysis and stabilization for continuous time-delay Takagi-Sugeno fuzzy systems. Based on the idea of delay fractioning, a new method is proposed for the delay-dependent stability analysis of fuzzy time-delay systems. Due to the instrumental idea of delay partitioning, the proposed stability condition is much less conservative than most of the existing results. The conservatism reduction becomes more obvious with the partitioning getting thinner. Based on this, the problem of stabilization via the so-called parallel distributed compensation scheme is also solved. Both the stability and stabilization results are further extended to time-delay fuzzy systems with time-varying parameter uncertainties. All the results are formulated in the form of linear matrix inequalities (LMIs), which can be readily solved via standard numerical software. The advantage of the results proposed in this paper lies in their reduced conservatism, as shown via detailed illustrative examples. The idea of delay partitioning is well demonstrated to be efficient for conservatism reduction and could be extended to solving other problems related to fuzzy delay systems. © 2009 IEEE.published_or_final_versio

Charm meson resonances in D→PℓνD \to P \ell \nu decays

Motivated by recent experimental results we reconsider semileptonic $D \to P \ell \nu_{\ell}$ decays within a model which combines heavy quark symmetry and properties of the chiral Lagrangian. We include excited charm meson states, some of them recently observed, in our Lagrangian and determine their impact on the charm meson semileptonic form factors. We find that the inclusion of excited charm meson states in the model leads to a rather good agreement with the experimental results on the $q^2$ shape of the $F_+(q^2)$ form factor. We also calculate branching ratios for all $D \to P \ell \nu_{\ell}$ decays.Comment: 9 pages, 4 figures; minor corrections, added some discussion, version as publishe