3,808 research outputs found
Phenomenological Consequences of Right-handed Down Squark Mixings
The mixings of quarks, hidden from view in Standard Model (SM), are
naturally the largest if one has an Abelian flavor symmetry. With supersymmetry
(SUSY) their effects can surface via squark loops. Squark and
gluino masses are at TeV scale, but they can still induce effects comparable to
SM in (or ) mixings, while mixing could be close to recent
hints from data. In general, CP phases would be different from SM, as may be
indicated by recent B Factory data. Presence of non-standard soft SUSY
breakings with large could enhance (or )
transitions.Comment: Version to appear in Phys. Rev. Let
Imaging Oxygen Defects and their Motion at a Manganite Surface
Manganites are technologically important materials, used widely as solid
oxide fuel cell cathodes: they have also been shown to exhibit
electroresistance. Oxygen bulk diffusion and surface exchange processes are
critical for catalytic action, and numerous studies of manganites have linked
electroresistance to electrochemical oxygen migration. Direct imaging of
individual oxygen defects is needed to underpin understanding of these
important processes. It is not currently possible to collect the required
images in the bulk, but scanning tunnelling microscopy could provide such data
for surfaces. Here we show the first atomic resolution images of oxygen defects
at a manganite surface. Our experiments also reveal defect dynamics, including
oxygen adatom migration, vacancy-adatom recombination and adatom bistability.
Beyond providing an experimental basis for testing models describing the
microscopics of oxygen migration at transition metal oxide interfaces, our work
resolves the long-standing puzzle of why scanning tunnelling microscopy is more
challenging for layered manganites than for cuprates.Comment: 7 figure
Evidence for Factorization in Three-body B --> D(*) K- K0 Decays
Motivated by recent experimental results, we use a factorization approach to
study the three-body B --> D(*) K- K0 decay modes. Two mechanisms are proposed
for kaon pair production: current-produced (from vacuum) and transition (from B
meson). The Bbar0 --> D(*)+ K- K0 decay is governed solely by the
current-produced mechanism. As the kaon pair can be produced only by the vector
current, the matrix element can be extracted from e+ e- --> K Kbar processes
via isospin relations. The decay rates obtained this way are in good agreement
with experiment. Both current-produced and transition processes contribute to
B- --> D(*)0 K- K0 decays. By using QCD counting rules and the measured B- -->
D(*)0 K- K0 decay rates, the measured decay spectra can be understood.Comment: 17 pages, 6 figure
Charmless Three-Body Baryonic B Decays
Motivated by recent data on B-> p pbar K decay, we study various charmless
three-body baryonic B decay modes, including Lambda pbar pi, Sigma0 pbar pi, p
pbar pi, p pbar Kbar0, in a factorization approach. These modes have rates of
order 10^{-6}. There are two mechanisms for the baryon pair production,
current-produced and transition. The behavior of decay spectra from these
baryon production mechanisms can be understood by using QCD counting rules.
Predictions on rates and decay spectra can be checked in the near future.Comment: 26 pages, 9 figures; version to appear in Phys. Rev.
Strong duality in conic linear programming: facial reduction and extended duals
The facial reduction algorithm of Borwein and Wolkowicz and the extended dual
of Ramana provide a strong dual for the conic linear program in the absence of any constraint qualification. The facial
reduction algorithm solves a sequence of auxiliary optimization problems to
obtain such a dual. Ramana's dual is applicable when (P) is a semidefinite
program (SDP) and is an explicit SDP itself. Ramana, Tuncel, and Wolkowicz
showed that these approaches are closely related; in particular, they proved
the correctness of Ramana's dual using certificates from a facial reduction
algorithm.
Here we give a clear and self-contained exposition of facial reduction, of
extended duals, and generalize Ramana's dual:
-- we state a simple facial reduction algorithm and prove its correctness;
and
-- building on this algorithm we construct a family of extended duals when
is a {\em nice} cone. This class of cones includes the semidefinite cone
and other important cones.Comment: A previous version of this paper appeared as "A simple derivation of
a facial reduction algorithm and extended dual systems", technical report,
Columbia University, 2000, available from
http://www.unc.edu/~pataki/papers/fr.pdf Jonfest, a conference in honor of
Jonathan Borwein's 60th birthday, 201
Recent advances on information transmission and storage assisted by noise
The interplay between nonlinear dynamic systems and noise has proved to be of
great relevance in several application areas. In this presentation, we focus on
the areas of information transmission and storage. We review some recent
results on information transmission through nonlinear channels assisted by
noise. We also present recent proposals of memory devices in which noise plays
an essential role. Finally, we discuss new results on the influence of noise in
memristors.Comment: To be published in "Theory and Applications of Nonlinear Dynamics:
Model and Design of Complex Systems", Proceedings of ICAND 2012 (Springer,
2014
Implications of Recent Measurements
The recent measurements of the color-suppressed modes imply non-vanishing relative final-state interaction (FSI)
phases among various decay amplitudes. Depending on whether or
not FSIs are implemented in the topological quark-diagram amplitudes, two
solutions for the parameters and are extracted from data using
various form-factor models. It is found that is not universal:
and with a relative phase
of order between and . If FSIs are not included in
quark-diagram amplitudes from the outset, and
will become smaller. The large value of compared to
or naive expectation implies the importance of
long-distance FSI contributions to color-suppressed internal -emission via
final-state rescatterings of the color-allowed tree amplitude.Comment: 17 pages. The Introduction is substantially revised and the order of
the presentation in Sec. 2 is rearranged. To appear in Phys. Re
The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene.
Neuregulin-1 (NRG1) is both a candidate oncogene and a candidate tumour suppressor gene. It not only encodes the heregulins and other mitogenic ligands for the ERBB family, but also causes apoptosis in NRG1-expressing cells. We found that most breast cancer cell lines had reduced or undetectable expression of NRG1. This included cell lines that had translocation breaks in the gene. Similarly, expression in cancers was generally comparable to or less than that in various normal breast samples. Many non-expressing cell lines had extensive methylation of the CpG island at the principal transcription start site at exon 2 of NRG1. Expression was reactivated by demethylation. Many tumours also showed methylation, whereas normal mammary epithelial fragments had none. Lower NRG1 expression correlated with higher methylation. Small interfering RNA (siRNA)-mediated depletion of NRG1 increased net proliferation in a normal breast cell line and a breast cancer cell line that expressed NRG1. The short arm of chromosome 8 is frequently lost in epithelial cancers, and NRG1 is the most centromeric gene that is always affected. NRG1 may therefore be the major tumour suppressor gene postulated to be on 8p: it is in the correct location, is antiproliferative and is silenced in many breast cancers
The Effect Of Refolding Conditions On The Protein Solubility Recovered From Inclusion Bodies
Recombinant proteins are expressed as inclusion bodies in bacterial enriched native-like secondary structure and thus give a great potential in biotechnological utilities. However, the quality of soluble proteins recovered from inclusion bodies is questionable because the refolded protein with wrong conformation will assemble to form aggregates. In this study, enhanced green fluorescent protein-inclusion bodies was used as the model protein to investigate the effects of protein concentration and purity on protein refolding. Three different types of solubized enhanced green fluorescent protein-inclusion bodies were refolded which were solubized inclusion bodies with cell debris, solubized inclusion bodies with detergent washing, and purified solubized inclusion bodies using preparative native urea-polyacrylamide gel electrophoresis. For the first and second conditions, the solubized enhanced green fluorescent protein-inclusion bodies were refolded at a high protein concentration and low protein purity environment. Polyacrylamide gel images show the refolded protein changed in conformation and increased in size when the solubized inclusion bodies underwent various refolding periods. Meanwhile, the refolded protein under the third refolding condition has a correct protein conformation and achieved the highest refolding yield. Studying the effects of refolding conditions using different types of solubized inclusion bodies may provide researchers with possible approaches to avoid soluble aggregates formation
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