Factors Determining Transit Access by Car Owners: Implications for Intermodal Passenger Transportation Planning

Although walking is the dominant mode of transportation to transit facilities, there are strong variations by socio-demographics, geography, mode of public transit used and other factors. There is particularly a need to understand ways in which car owners who choose to use public transportation can be encouraged to carpool, walk or bicycle in the “first mile” and “last mile” of the transit trip, instead of driving. These considerations have implications for addressing cold start trips resulting from short drives to transit facilities, active transportation strategies that may benefit transit users who currently drive, and in deriving solutions for shared transportation such as bicycle-sharing and car-sharing programs. Using data collected in the Chicago Metropolitan Area, we investigate how the mode choice for the access trip to transit stations is related to costs, personal and household variables, trip characteristics, and neighborhood factors including crash frequencies, crime prevalence, neighborhood racial characteristics, population density, roadway density etc. for persons in car owning households. The results suggest that while much of the choice depends on personal and trip related variables, some neighborhood level factors as well as the provision of parking at transit stations have important relationships to mode choice that can influence built environment factors such as density and policy areas such as the provision and operation of transit parking facilities

Feed resources availability, utilization and marketing in central and eastern Tigray, northern Ethiopia

This survey explored the situation of different feed resources for ruminant livestock in two zones (central and eastern) in Tigray region of northern Ethiopia. These two zones account for the region’s 12% of the total land mass, 23% of the human population, 28% of the cattle population, and 56% of the small ruminant population. Farmers feed their livestock a variety of feed resources that range from crop residues to non-conventional feeds.The overall contribution of crop residues exceeds 50% of the livestock feeds currently used by smallholder farmers, and this reflects the level of integration between crop and livestock farming. Overall, the management and utilization of crop residues with particular attention to collection and transportation is constrained by factors such as labour shortage, distance from harvesting field to animals and delayed harvest in the project districts. Grazing land management and improvement is seldom considered by farmers or the extension system. Acute shortages of AIBPs supply from the sources and high price fluctuation in the main towns of the districts are discouraging smallholder dairy and small ruminant farmers from using them on a regular basis. The contribution of improved forage plants is not as expected and forage genetic material multiplication sites are operating with insufficient budget and manpower, and not supported by proper research. The overall feed supply to demand ratio in four districts in the eastern zone is not enough to cover the annual maintenance requirements of the present stock

Predictors of Treatment Seeking Intention among People with Cough in East Wollega, Ethiopia Based on the Theory of Planned Behavior: A Community Based Cross -Sectional Study

Background: Early treatment seeking for cough is crucial in the prevention and control of Tuberculosis. This study was intended to assess treatment seeking intention of people with cough of more than two weeks, and to identify its predictors.Methods: A community based cross-sectional study was conducted among 763 individuals with cough of more than two weeks in East Wollega Zone from March 10 to April 16, 2011. Study participants were selected from eighteen villages by cluster sampling method. Data collection instruments were developed according to the standard guideline of the theory of planned behavior. The data were analyzed with SPSS 16.0. Multiple linear regression was used to identify predictors.Results: Mean score of intention was found to be 12.6 (SD=2.8) (range of possible score=3-15). Knowledge (β=0.14, 95%CI: 0.07-0.2), direct attitude (β=0.31, 95%CI: 0.25-0.35), belief-based attitude (β=0.03, 95%CI: 0.02-0.06) and perceived subjective norm (β=0.22, 95%CI: 0.13 -0.31) positively predicted treatment seeking intention. However, perceived behavioral control and control belief were not significantly associated with treatment seeking intention (p>0.05). Being smoker (β=-0.97, 95%CI:-1.65- (-0.37)) and higher family income (β=-0.06, 95%CI:-0.07-(-0.01) were significantly associated with lower treatment seeking intention.Conclusion: TPB significantly predicted treatment seeking intention among the study participants. Attitude and silent beliefs held by the respondents play an important role and should be given emphasize in prevention and control of Tuberculosis.Keywords: Tuberculosis, Cough, Intention, Treatment, Theory of Planned Behavio

Nuclear ribosomal DNA diversity of a cotton pest (Rotylenchulus reniformis) in the United States

The reniform nematode (Rotylenchulus reniformis) has emerged as a major cotton pest in the United States. A recent analysis of over 20 amphimictic populations of this pest from the US and three othercountries has shown no sequence variation at the nuclear ribosomal internal transcribed spacer (ITS) despite the region’s usual variability. We investigated this unexpected outcome by amplifying, cloningand sequencing two regions of the nuclear ribosomal DNA (18S, ITS1) to ascertain whether any variation occurred within and among populations of reniform nematodes in Alabama, US. Both thenrITS1 and the relatively conserved 18S region showed a fairly substantial amount of variation among populations. The identity among ITS sequences ranged from 1.00 to 0.86, while sequence identity at the18S ranged from 1.00 to 0.948. We conclude that variation does exist in these sequences in reniform nematodes, and the earlier report showing no ribosomal ITS variation in this pest might have beencaused by preferential amplification of a conserved ITS paralog. Current and future application towards resistance in cotton varieties to this pest requires reliable information on the molecular variability of thenematode in cotton-growing areas

Challenges and opportunities to improve autism services in low-income countries: lessons from a situational analysis in Ethiopia

Background. Little has been reported about service provision for children with autism in low-income countries. This study explored the current service provision for children with autism and their families in Ethiopia, the existing challenges and urgent needs, and stakeholders’ views on the best approaches to further develop services. Methods. A situational analysis was conducted based on i) qualitative interviews with existing service providers; ii) consultation with a wider group of stakeholders through two stakeholder workshops; and iii) information available in the public domain. Findings were triangulated where possible. Results. Existing diagnostic and educational services for children with autism are scarce and largely confined to Ethiopia’s capital city, with little provision in rural areas. Families of children with autism experience practical and psychosocial challenges, including severe stigma. Informants further raised the lack of culturally and contextually appropriate autism instruments as an important problem to be addressed. The study informants and local stakeholders provided several approaches for future service provision expansion, including service decentralisation, mental health training and awareness raising initiatives. Conclusions. Services for children with autism in Ethiopia are extremely limited; appropriate care for these children is further impeded by stigma and lack of awareness. Ethiopia’s plans to scale up mental healthcare integrated in primary healthcare provides an opportunity to expand services for children with autism and other developmental disorders. These plans and additional strategies outlined in this paper can help to address the current service provision gaps and may also inform service enhancement approaches in other low-income countries

Chimeric Anti-Staphylococcal Enterotoxin B Antibodies and Lovastatin Act Synergistically to Provide In Vivo Protection against Lethal Doses of SEB

Staphylococcal enterotoxin B (SEB) is one of a family of toxins secreted by Staphylococcus aureus that act as superantigens, activating a large fraction of the T-cell population and inducing production of high levels of inflammatory cytokines that can cause toxic shock syndrome (TSS) and death. Extracellular engagement of the TCR of T-cells and class II MHC of antigen presenting cells by SEB triggers the activation of many intracellular signaling processes. We engineered chimeric antibodies to block the extracellular engagement of cellular receptors by SEB and used a statin to inhibit intracellular signaling. Chimeric human-mouse antibodies directed against different neutralizing epitopes of SEB synergistically inhibited its activation of human T-cells in vitro. In the in vivo model of lethal toxic shock syndrome (TSS) in HLA-DR3 transgenic mice, two of these antibodies conferred significant partial protection when administered individually, but offered complete protection in a synergistic manner when given together. Similarly, in vivo, lovastatin alone conferred only partial protection from TSS similar to single anti-SEB antibodies. However, used in combination with one chimeric neutralizing anti-SEB antibody, lovastatin provided complete protection against lethal TSS in HLA-DR3 transgenic mice. These experiments demonstrate that in vivo protection against lethal doses of SEB can be achieved by a statin of proven clinical safety and chimeric human-mouse antibodies, agents now widely used and known to be of low immunogenicity in human hosts

Arresting gully formation in the Ethiopian highlands

Over the past five decades, gullying has been widespread and has become more severe in the Ethiopian highlands. Only in very few cases, rehabilitation of gullies has been successful in Ethiopia due to the high costs. The objective of this paper is to introduce cost effective measures to arrest gully formation. The research was conducted in the Debre-Mewi watershed located at 30 km south of Bahir Dar, Ethiopia. Gullying started in the 1980s following the clearance of indigenous vegetation and intensive agricultural cultivation, leading to an increase of surface and subsurface runoff from the hillside to the valley bottoms. Gully erosion rates were 10–20 times the measured upland soil losses. Water levels, measured with piezometers, showed that in the actively eroding sections, the water table was in general above the gully bottom and below it in the stabilized sections. In order to develop effective gully stabilizing measures, we tested and then applied the BSTEM and CONCEPT models for their applicability for Ethiopian conditions where active gully formation has been occurring. We found that the model predicted the location of slips and slumps well with the observed groundwater depth and vegetation characteristics. The validated models indicated that any gully rehabilitation project should first stabilize the head cuts. This can be achieved by regrading these head cuts to slope of 40 degrees and armoring it with rock. Head cuts will otherwise move uphill in time and destroy any improvements. To stabilize side walls in areas with seeps, grass will be effective in shallow gullies, while deeper gullies require reshaping of the gullies walls, then planting the gully with grasses, eucalyptus or fruit trees that can be used for income generation. Only then there is an incentive for local farmers to maintain the structures