53 research outputs found
Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy
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Time-Resolved Protein Phosphorescence in the Stopped-Flow: Denaturation of Horse Liver Alcohol Dehydrogenase by Urea and Guanidine Hydrochloride
No full textFluvastatin increases tyrosinase synthesis induced by UVB irradiation of B16F10 melanoma cells.
No full textStatins are widely used to lower plasma concentrations of lipids, e.g. cholesterol. One of the main effects of statin treatment is inhibition of hydroxymethyl glutaryl-coenzyme A reductase. The role of fluvastatin, a frequently used statin, was examined in potential modulation of tyrosinase (key enzyme of melanogenesis) synthesis. Levels of tyrosinase mRNA induced by UVB irradiation of B16F10 melanoma cell line were measured by real time PCR. Fluvastatin increases tyrosinase mRNA production induced by UVB irradiation in B16F10 melanoma cell line. Fluvastatin treatment may potentially influence melanin synthesis and protection against UV irradiation
Identifying Novel Molecular Structures for Advanced Melanoma by Ligand-Based Virtual Screening
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Boron Attenuates Heat Stress–Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells
No full textPreadaptation for parthenogenetic colony foundation in subterranean termites Reticulitermes spp. (Isoptera: Rhinotermitidae)
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