4,599 research outputs found

    Proposed business plan for pilot farmer organizations: Extended project on Farmer Managed Irrigated Agriculture in LBOD Project Area of Sindh Province

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    Farmers' associations / Farmer managed irrigation systems / Irrigation programs / Irrigation management / Drainage / Economic aspects / Income / Operating costs / Maintenance costs / Conflict

    Equivalent Circuit Modeling of the Dielectric Loaded Microwave Biosensor

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    This article describes the modeling of biological tissues at microwave frequency using equivalent lumped elements. A microwave biosensor based on microstrip ring resonator (MRR), that has been utilized previously for meat quality evaluation is used for this purpose. For the first time, the ring-resonator loaded with the lossy and high permittivity dielectric material, such as; biological tissue, in a partial overlay configuration is analyzed. The equivalent circuit modeling of the structure is then performed to identify the effect of overlay thickness on the resonance frequency. Finally, the relationship of an overlay thickness with the corresponding RC values of the meat equivalent circuit is established. Simulated, calculated and measured results are then compared for validation. Results are well agreed while the observed discrepancy is in acceptable limit

    New Lie group of transformation for the non-Newtonian fluid flow narrating differential equations

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    In this endeavour, a new Lie point of transformation for the fluid flow narrating differential equations are proposed. For this purpose a non-Newtonian fluid named tangent hyperbolic fluid is considered towards the flat surface in a magnetized flow field. In addition, equation of concentration admits the role of chemically reactive species. A mathematical model in terms of the coupled PDE’s is constructed. Lie group of analysis is implemented to yield the new Lie point of transformation for tangent hyperbolic fluid flow narrating differential equations when the heat and mass transfer individualities are considered. The resultant system of PDE’s is reduced into system of ODE’s via obtained set of transformation. The self-coded computational scheme is accomplished and the outcomes are reported by way of graphs. It is noticed that tangent hyperbolic fluid velocity, temperature and concentration is decreasing function of magnetic field parameter, Prandtl number and chemical reaction parameter respectively

    Data reduction of average friction factor of gas flow through adiabatic micro-channels

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    This paper presents data reduction of average friction factor of gas flow through adiabatic microchannels. In the case of micro-channel gas flow at high speed, the large expansion occurs near the outlet and the pressure gradient along the length is not constant with a significant increase near the outlet. This results in flow acceleration and a decrease in gas temperature. Therefore the friction factor of microchannel gas flow should be obtained with measuring both the pressure and temperature. The data reductions on friction factors were carried out under the assumption of isothermal flow for numerous experimental and numerical studies since temperature measurement of micro-channel gas flow at high speed is quite difficult due to the measurement limitations. In the previous study, it was found that the gas temperature can be determined by the pressure under the assumption of one dimensional flow in an adiabatic channel (Fanno flow). Therefore in the present study data reduction to estimate friction factors between two relatively distant points considering the effect of a decrease in temperature is introduced with the temperature determined by the measured pressure at a specific location. The Friction factors obtained by using the present data reduction are examined with the available literature and the results are compared with empirical correlations on Moody chart

    Design and Analysis of Even-Positioned Cavity - Based Optical Amplification Device in Dielectric Metasurface

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    Recently, the development in the field of optical technology is exemplary, specifically relating to the design of the components necessary for optical integrated circuits. This research work investigates optical amplification action in a 2D Photonic Crystals (PhCs) structure with variable radius even-positioned PhC-cavity within its lattice. Twooptical signals are used, first acting as data signals coupled into the optical structure using the phenomenon of the Guided-mode-resonances (GMR) and the second one as a pump signal index-guided into the optical structure. The pump signal is used to amplify the data signal and the PhC-cavity is used for spectral tuning of the device operating in near-infrared (NIR) range. The dielectric structure consists of an optical waveguide packed in between the substrate and a cladding layer. The design and analysis of the proposed device is performed in a Finite-Difference-Time-Domain (FDTD) based open-source software package. The investigated results present optical amplific

    Data reduction of average friction factor of gaseous flow in micro-channels with adiabatic wall

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    This study focuses on data reduction of average friction factor of gaseous flow through microchannels. In the case of microchannel gas flow at high speed, the large expansion occurs near the outlet and the pressure gradient along the length is not constant and increases near the outlet. This results in flow acceleration and a decease in bulk temperature. Therefore both pressure and temperature are required to obtain the friction factor of the microchannel gas flow. In the past data reduction of many experiments, the friction factors have been obtained under the assumption of isothermal flow since temperature measurement of compressible flow in micro-channels is quite difficult due to the experimental technique limitations. Kawashima and Asako [1] found that the gas temperature can be determined by the pressure under the assumption of one dimensional flow in an adiabatic channel (Fanno flow) to obtain the friction factor considering the effect of a decrease in gas temperature

    YAP Inhibition by Verteporfin Causes Downregulation of Desmosomal Genes and Proteins Leading to the Disintegration of Intercellular Junctions

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    The Hippo-YAP pathway serves as a central signalling hub in epithelial tissue generation and homeostasis. Yes-associated protein (YAP) is an essential downstream transcription cofactor of this pathway, with its activity being negatively regulated by Hippo kinase-mediated phosphorylation, leading to its cytoplasmic translocation or degradation. Our recent study showed phospho-YAP complexes with Desmoglein-3 (Dsg3), the desmosomal cadherin known to be required for junction assembly and cell–cell adhesion. In this study, we show that YAP inhibition by Verteporfin (VP) caused a significant downregulation of desmosomal genes and a remarkable reduction in desmosomal proteins, including the Dsg3/phospho-YAP complex, resulting in attenuation of cell cohesion. We also found the desmosomal genes, along with E-cadherin, were the YAP-TEAD transcriptional targets and Dsg3 regulated key Hippo components, including WWTR1/TAZ, LATS2 and the key desmosomal molecules. Furthermore, Dsg3 and phospho-YAP exhibited coordinated regulation in response to varied cell densities and culture durations. Overexpression of Dsg3 could compensate for VP mediated loss of adhesion components and proper architecture of cell junctions. Thus, our findings suggest that Dsg3 plays a crucial role in the Hippo network and regulates junction configuration via complexing with phospho-YAP

    Analysis of landslide movements using interferometric synthetic aperture radar: A case study in Hunza-Nagar Valley, Pakistan

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    From a geological standpoint, northern Pakistan is one of the most active and unstable areas in the world. As a consequence, many massive landslides have occurred in the area in historical times that have destroyed infrastructure, blocked the Hunza River, and damaged the Karakoram Highway repeatedly. However, despite the high frequency of large magnitude landslide events, and the consequent damages, the entire area is largely understudied, mainly due to the difficult logistics and the large distances involved. This work is aimed at applying the potential use of Interferometric Synthetic Aperture Radar (InSAR) for landslide identification and investigation for the Hunza-Nagar Region. Sentinel-1 images covering a period of more than two years (February 2017-August 2019) were used and processed by adopting the small baseline subset (SBAS) method. The obtained deformation rate measured along the line of sight (VLOS) varies from -114 to 20 mm/year. The downslope velocity deformation rates (Vslope) range from 0 to -300 mm/year. The Vslope stability threshold for our study area was calculated to be -14 mm/year from the Vslope standard deviation. Four active landslides with Vslope exceeding 14 mm/year were recognizable and have been confirmed by field inspection. The identified landslides listed from the most active to least active are the Humarri, Mayoon, Khai, and Ghulmet landslides, respectively. VLOS exceeding 114 mm/year was observed in the Humarri landslide, which posed a threat of damming a lake on the Hispar River and was also a risk to the Humarri Village located below the landslide. The maximum mean deformation detected in the Ghulmet, andMayoon landslide was in the order of 30 mm/year and 20 mm/year, respectively. More importantly, it was found that in places, the slope deformation time series showed a patchy correlation with precipitation and seismic events in the area. This may indicate a complex, and possibly uncoupled, relationship between the two controlling agents promoting the deformation. However, the collective impact of the two factors is evident in the form of a continuously descending deformation curve and clearly indicates the ground distortion. The results indicate a potentially critical situation related to the high deformation rates measured at the Humarri landslide. On this specific slope, conditions leading to a possible catastrophic failure cannot be ruled out and should be a priority for the application of mitigation measures

    Fourth-generation SM imprints in B -> K^*l^+l^- decays with polarized K^*

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    The implication of the fourth-generation quarks in the B -> K^*l^+l^- (l=mu,tau) decays, when K^* meson is longitudinally or transversely polarized, is presented. In this context, the dependence of the branching ratio with polarized K^* and the helicity fractions (f_{L,T}) of K^* meson are studied. It is observed that the polarized branching ratios as well as helicity fractions are sensitive to the NP parameters, especially when the final state leptons are tauons. Hence the measurements of these observables at LHC can serve as a good tool to investigate the indirect searches of new physics beyond the Standard Model.Comment: 13 pages, 10 figures, V2: some of the graphs are modified according to the new data from recent experiments. arXiv admin note: substantial text overlap with arXiv:1107.569
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