Multi-Scale Deformable Alignment and Content-Adaptive Inference for Flexible-Rate Bi-Directional Video Compression

The lack of ability to adapt the motion compensation model to video content is an important limitation of current end-to-end learned video compression models. This paper advances the state-of-the-art by proposing an adaptive motion-compensation model for end-to-end rate-distortion optimized hierarchical bi-directional video compression. In particular, we propose two novelties: i) a multi-scale deformable alignment scheme at the feature level combined with multi-scale conditional coding, ii) motion-content adaptive inference. In addition, we employ a gain unit, which enables a single model to operate at multiple rate-distortion operating points. We also exploit the gain unit to control bit allocation among intra-coded vs. bi-directionally coded frames by fine tuning corresponding models for truly flexible-rate learned video coding. Experimental results demonstrate state-of-the-art rate-distortion performance exceeding those of all prior art in learned video coding.Comment: Accepted for publication in IEEE International Conference on Image Processing (ICIP) 202

Impact of laboratory test use strategies in a Turkish hospital

Objectives: Eliminating unnecessary laboratory tests is a good way to reduce costs while maintain patient safety. The aim of this study was to define and process strategies to rationalize laboratory use in Ankara Numune Training and Research Hospital (ANH) and calculate potential savings in costs. Methods: A collaborative plan was defined by hospital managers; joint meetings with ANHTA and laboratory professors were set; the joint committee invited relevant staff for input, and a laboratory efficiency committee was created. Literature was reviewed systematically to identify strategies used to improve laboratory efficiency. Strategies that would be applicable in local settings were identified for implementation, processed, and the impact on clinical use and costs assessed for 12 months. Results: Laboratory use in ANH differed enormously among clinics. Major use was identified in internal medicine. The mean number of tests per patient was 15.8. Unnecessary testing for chloride, folic acid, free prostate specific antigen, hepatitis and HIV testing were observed. Test panel use was pinpointed as the main cause of overuse of the laboratory and the Hospital Information System test ordering page was reorganized. A significant decrease (between 12.6-85.0%) was observed for the tests that were taken to an alternative page on the computer screen. The one year study saving was equivalent to 371,183 US dollars. Conclusion: Hospital-based committees including laboratory professionals and clinicians can define hospital based problems and led to a standardized approach to test use that can help clinicians reduce laboratory costs through appropriate use of laboratory test

The effect of IL-1B and specific ice/caspase-1 bloker on spike-and-wave discharges

İstanbul Bilim Üniversitesi, Tıp Fakültesi.Purpose: Interleukin (IL)-1b plays a crucial role in the mechanisms of limbic seizures induced in rodent models of temporal lobe epilepsy. We addressed whether activation of the IL-1b signaling occurs in rats with genetic absence epilepsy (GAERS) during the development of spike-andwave discharges (SWDs). Moreover, we studied whether inhibition of IL-1b biosynthesis could affect SWD activity.http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2011.03207.x/pd

Effects of adipose and bone marrow-derived mesenchymal stem cells on vaginal atrophy in a rat menopause model

Background & objectives: Vaginal atrophy is characterized by thinning of vaginal epithelial layers and decreased local blood flow. We aimed to evaluate the regenerative effects of Adipose derived mesenchymal stem cells (ADMSC) and Bone marrow derived mesenchymal stem cells (BMDSC) on vaginal atrophy in rat menopause model. Materials and methods: Rats were randomly divided into 4 (four) groups: sham, control, ADMSC, BMDSC. Vaginal epithelial thickness, structure of the lamina propria, blood vessels in the lamina propria, collagen deposition, and muscle structure were evaluated. Anti ER α, VEGF, VEGFR 1, Bax and bcl-2 antibodies were analyzed. Beta actin gene was used as endogenous control. Genetical differences among the groups were compared by using Kruskal Wallis and Mann Whitney U test. p < 0.05 was regarded as statistically significant. Results: Epithelial thickness of ADMSC group was higher than control group, but less than sham group Epithelial thickness of BMDSC group was less than sham group. Lamina propria and muscle tissue of ADMSC and BMDSC groups were found to be similar to sham group. VEGFR-1, VEGF, Bax and ER-α staining levels were higher in ADMSC and BMDSC groups than control group. ADMSC group stained stronger with VEGFR-1 and VEGF than BMDSC group. Bcl-2 staining level was increased in ADMSC applied group. No statistically significant difference was detected in Bax and Bcl-2 genes and Bax-/Bcl-2 ratio. Conclusions: Although genetic expression might have ended and could not be significantly demonstrated, histological and immunohistochemical results favor ADMSC application in vaginal atrophy rather than BMDSC. © 2019 Elsevier B.V

Design and analysis of zero cogging torque brusless DC motor for spaceeraft applications

Abstract Control moment gyroscopes (CMG) are used in modern satellite applications for attitude control of satellites References [1] S. P. Bhat and P. Tiwari, &quot;Controllability of spacecraft attitude using control moment gyroscopes,&quot; IEEE Transactions on Automatic Control, vol. 54,NO. 3, pp. 585-590, March 2009. [2] R. P. Praven, &quot;Design and analysis of zero cogging torque brusless DC motor for spaceeraft applications,&quot; Proc. International Conference ECTI-CON, pp. 254-258, May 2010