Therapeutic effect of magnesium sulphate on carbon monoxide toxicity-mediated brain lipid peroxidation

CONCLUSIONS: CO poisoning caused significant damage, detected within the first 6 hours. Due to antioxidant enzymes, especially GSH-Px activity reaching the top level within 24th hours, significant oxidative damage was not observed. The protective effect against oxidative damage of magnesium sulfate has been identified within the first 6 hours

Assessment of the applications to Kocaeli derince research and education hospital in 2012 and 2013 to obtain disabled children’s health board report

In this study, it is aimed to determine the neurodevelopmental disorders of children and adolescents applied to health committee for the disability, in a definite period. Cases of 0-18 aged 1512 children and adolescents who applied to health committee of our hospital between January 2012-December 2013 were analysed retrospectively. The study included cases whose 37.6% (569) were female and 62.4% (943) were male. The mean age was 7.66±3.8. 36.3% (549) of the cases were in the range of 0-6 years of age, 63.7% (963) of the cases were in the range of 7-18 years of age. The most common diagnoses were developmental delays in the range of 0-6 years of age and intellectual disability in the range of 7-18 years of age. Results of such studies investigating the applications will contribute to the statistical data of disabled population in our country, and will faciliate the organisation of social and educational rights of disabled children and adolescents applied to the health committees. Copyright © 2014 OMU

Bilek güreşi sırasında humerusun spiral kırığı

Arm wrestling contests have become a common pub and even professional sport. Although armwrestling injuries are not common, several have been reported in the medical literature. In this case, spiral fracture of the humerus with large free fragments which had occurred during arm wrestling and occurring mechanism of injury was attracted attention. It is concluded that arm wrestling should not be considered a completely harmless sport and it appears appropriate to warn public and arm wrestler against arm wrestling.Bilek güreşi müsabakaları halk arasında ve hatta profesyonel sporcular arasında yaygın bir şekilde yapılmaktadır. Bilek güreşi yaralanmaları çok sık olmamasına rağmen, tıbbi literatürde bir kaç yayın rapor edilmiştir. Bu vakada bilek gü- reşi sırasında meydana gelen, serbest kemik parçası olan humerusun spiral cisim kırığına ve travmanın oluş mekanizmasına dikkat çekildi. Bilek güreşinin tamamiyle zarasız bir spor olarak düşünülmemesi gerektiği ve bilek güreşine karşı bu sporla uğraşan profesyonel sporcuların ve halkın uyarılmasının uygun olduğu sonucuna varıldı

Royal jelly can diminish secondary neuronal damage after experimental spinal cord injury in rabbits

The aim of this experimental study was to investigate the neuroprotective effect of Royal jelly (RJ) on traumatic spinal cord injury (SCI). Twenty-one New Zealand male rabbits, weighing between 2.5 and 3.0 kg were divided into three groups: Sham (no drug or operation, n = 7), Control (laminectomy + single dose of 1 ml/kg saline orally, after trauma; n = 7) and RJ (laminectomy + 100 mg/kg RJ, orally, after trauma, n = 7). Laminectomy was performed at T10 and balloon catheter was applied extradurally for traumatic SCI. Four and 24 h after surgery, rabbits were evaluated according to the Tarlov scoring system. Blood, cerebrospinal fluid and tissue sample from spinal cord were taken for measurements of antioxidant status or detection of apoptosis. Four hours after SCI, all animals in control or RJ treated groups became paraparesic. Significant improvement was observed in RJ treated group, 24 h after SCI, with respect to control. Traumatic SCI led to increase in the lipid peroxidation and decrease enzymic or non-enzymic endogenous antioxidative defense systems, and increase in apoptotic cell numbers. RJ treatment mostly prevented lipid peroxidation and also augmented endogenous enzymic or non-enzymic antioxidative defense systems. Again, RJ treatment significantly decreased the apoptotic cell number induced by SCI. (C) 2012 Elsevier Ltd. All rights reserved

Violence against emergency department employees and the attitude of employees towards violence

Conclusion: Violence against employees in the emergency department is a widespread problem. This situation has a strong negative effect on employee satisfaction and work performance. In order to reduce the incidence of violence in the emergency department, both patients and their families should be better informed so they have realistic expectations as an emergency patient, deterrent legal regulations should be put in place, and increased efforts should be made to provide enhanced security for emergency department personnel. These measures will reduce workplace violence and the stress experienced by emergency workers. We expect this to have a positive impact on emergency health care service delivery

Effectiveness of GFAP in Determining Neuronal Damage in Rats with Induced Head Trauma

CONCLUSION: Serum GFAP concentration can be used as a marker of the severity of head trauma and traumatic brain injury. However, more animal studies are required to reflect this result in clinical practice

Thiol/disulfide homeostasis as a novel indicator of oxidative stress in children with simple febrile seizures

Simple febrile seizures are generally benign, but during the seizure, elevated levels of glutamate and high levels of oxygen use due to the high metabolic brain activity result in oxidative stress. However, the relationship between febrile seizures and oxidative stress remains unclear. In this study, we investigated thiol/disulfide homeostasis as a new oxidative stress parameter in patients with simple febrile seizures. This study was performed between February 2016 and May 2016 at the Pediatric Emergency Unit. The study population consisted of 40 patients with a diagnosis of simple febrile seizure and 30 control participants aged 8-59 months. Total thiol, native thiol and disulfide levels, disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol ratios were used as thiol/disulfide homeostasis parameters and were quantified in patient and control groups. Furthermore, correlations with seizure duration were investigated. In the patient group, native and total thiol levels and native thiol/total thiol ratios were low, and disulfide levels, disulfide/native thiol, and disulfide/total thiol ratios were significantly higher than in the control group. Negative correlations were observed between seizure duration, total and native thiol levels, and native thiol/total thiol ratio, whereas positive correlations were observed between seizure duration and disulfide/native thiol and disulfide/total thiol ratio. The sensitivities of both disulfide/native thiol and disulfide/total thiol ratios were high for simple febrile seizures. Simple febrile seizures may cause impairment in favor of disulfide bonds in thiol/disulfide homeostasis. Overall, these changes may contribute to neuronal cell damage after simple febrile seizures

TRAUMATIC ISOLATED PERICARDIO-DIAPHRAGMATIC RUPTURE

Pericardio-diaphragmatic rupture is an uncommon problem that poses a diagnostic challenge to surgeons. This article reports an unusual case of traumatic pericardio-diaphragmatic rupture in a 36-year-old male who has no additional intraabdominal visceral injury or thoracic pathology. There was a 7 cm lateral tear on the left dome of the diaphragm and a 2 cm medial tear, also involving pericardio-diaphragmatic junction, with the heart uninjured. The partially herniated stomach was easily pulled out from the thorax cavity through the diaphragmatic rupture. The rupture was reparied by interrupted non-absorbable sutures. The patient had no complaints on his follow up

Bilek güreşi sırasında humerusun spiral kırığı

Arm wrestling contests have become a common pub and even professional sport. Although armwrestling injuries are not common, several have been reported in the medical literature. In this case, spiral fracture of the humerus with large free fragments which had occurred during arm wrestling and occurring mechanism of injury was attracted attention. It is concluded that arm wrestling should not be considered a completely harmless sport and it appears appropriate to warn public and arm wrestler against arm wrestling.Bilek güreşi müsabakaları halk arasında ve hatta profesyonel sporcular arasında yaygın bir şekilde yapılmaktadır. Bilek güreşi yaralanmaları çok sık olmamasına rağmen, tıbbi literatürde bir kaç yayın rapor edilmiştir. Bu vakada bilek gü- reşi sırasında meydana gelen, serbest kemik parçası olan humerusun spiral cisim kırığına ve travmanın oluş mekanizmasına dikkat çekildi. Bilek güreşinin tamamiyle zarasız bir spor olarak düşünülmemesi gerektiği ve bilek güreşine karşı bu sporla uğraşan profesyonel sporcuların ve halkın uyarılmasının uygun olduğu sonucuna varıldı