Association between NFKB1

Nuclear factor-κB is associated with the pathogenesis of numerous malignancies, and the functional polymorphism −94ins/del ATTG (rs28362491) in the human NFKB1 gene is associated with cancer risk. Previous studies on the association between the −94ins/del ATTG polymorphism and cancer risk reported conflicting results. To clarify this relationship, we performed a meta-analysis of 21 case-control studies involving 6127 cases and 9238 controls. We used pooled odds ratios (ORs) with their 95% confidence intervals (95% CIs) to assess the association. We found that the NFKB1 promoter −94ins/del ATTG polymorphism was significantly associated with cancer risk in four genetic models (ins/ins versus del/del, OR = 1.47, 95% CI = 1.11–1.93; dominant model, OR = 1.26, 95% CI = 1.03–1.53; recessive model, OR = 1.26, 95% CI = 1.05–1.51; ins allele versus del allele, OR = 1.19, 95% CI = 1.05–1.35). Stratified analyses revealed a significant association between the polymorphism and ovarian, oral, and prostate cancers. Similar results were determined in an Asian population and not in a Caucasian population. Thus, our results suggested that the polymorphism can contribute to cancer risk. Moreover, the polymorphism can exert race- and cancer-specific effects on cancer risk. Further large-scale and functional studies are necessary to elucidate this possible effect

Fe3C doped modified nano-Si/C composites as high-coulombic-efficiency anodes for lithium-ion batteries

Silicon is considered to be the most promising candidate for the anode of high energy density lithium-ion batteries. Nanometerization has been proven to be an effective method for improving the stress accumulation caused by the volume expansion of silicon. However, new issues such as poor initial coulombic efficiency (ICE) need to be solved because nanostructure silicon has an increased specific surface area. Here, a doping modification strategy is developed by a solvothermal combined with low-pressure gas-solid conversion reaction, and innovatively formed an Fe3C/N co-doped carbon coating on the nano-silicon surface. The doping of Fe3C in the composite material can catalyze the formation of a thin and stable solid electrolyte interphase (SEI) on the electrode surface and serve as a framework to stabilize the electrode structure during charge and discharge. As a result, Fe3C doping can significantly increase the ICE of the electrode from 66.4% to 87.1%, and the stable efficiency exhibited a rapid increase upwards of 99.5% after only 6 cycles including the first formation cycle, compared to the non-doped structure. The modified nano-silicon with Fe3C doping can provide high reversible capacity (1443.3 mA h g(-1) after 200 cycles at 0.2 A g(-1)) and long cycle life (74% capacity retention after 1000 cycles at 0.5 A g(-1))

Short-Process Multiscale Core-Shell Structure Buffer Control of a Ni/N Codoped Si@C Composite Using Waste Silicon Powder for Lithium-Ion Batteries

A huge amount of waste silicon powder produced in the solar energy silicon wafer production process causes resource wastage and environmental pollution. As a lithium-ion battery anode, silicon has received widespread attention because of its extremely high theoretical specific capacity, abundance in nature, and low discharge potential. However, the large volume expansion and huge internal stresses lead to instability of the solid-state interphase layer upon lithiation/delithiation; it is the problem that needs to be solved for actual application of silicon-based anodes. Here, based on the waste silicon powder from a photovoltaic silicon production process as the raw material, we propose a concept of short-process multiscale structure buffer control and prepare Ni-N codoped Si@C core-shell composites to solve the abovementioned problems. The preparation method is simple and nonpolluting and has positive significance for realizing industrialization. For structure, the Si particles are completely encapsulated by the nanoscale carbon shell, and the suitable elastic buffer carbon shell can accommodate Si expansion and the introduction of metallic nickel and N can improve the electrode material conductivity and utilize the metal ductility to buffer the silicon volume expansion during the process of charge/discharge. As a result, the Ni-N codoped sigc electrode shows a stable reversible specific capacity of 1001.5 mAh g(-1) at 0.5 A g(-1) after 450 cycles

Effects of electrolyte recycling on desulfurization from bauxite water slurry electrolysis

To lower the cost of bauxite electrolysis desulfurization using NaOH solution as the supporting electrolyte, effects of electrolyte recycling on bauxite electrolysis desulfurization were investigated. The results indicate that electrode corrosion, cell voltage, the desulfurization rate and the pH value of the electrolyte have no obvious changes with the increase of cycle times. Additionally, there were some transitive valence S-containing ions in electrolyte after the electrolysis, such as SO32, S2O32. However, most of the sulfur in bauxite was eventually oxidized into SO42- into the electrolyte, and these S-containing ions did not affect the recycling utilization for electrolyte

Constructing an artificial boundary to regulate solid electrolyte interface formation and synergistically enhance stability of nano-Si anodes

Low coulombic efficiency and poor cyclic stability are two common problems for silicon anodes. Therefore, it is of great significance to improve cycling performance and initial coulombic efficiency (ICE) via rational surface engineering on nano-Si anodes. Herein, a new nano-silicon anode is obtained by straightforward constructing a multifunctional polypyrrole protective layer on the surface of silicon nanoparticles, which is further used as the inner boundary of solid electrolyte interface (SEI) film. Specifically, the Li salt decomposition reaction between the electrolyte and silicon surface is effectively inhibited under the protection of the compact artificial boundary. The transfer of Li+ for forming the SEI film is selectively slower than that of lithiation/delithiation reaction. This further reduces the amount of SEI film, leading to a high ICE of 93.2% at 0.5 A g(-1) for modified nano-Si anodes. In addition, the flexible SEI precursor combined with the high proportion of organic components in SEIs not only accommodates the volume change of nano-silicon, but also suppresses accumulation of "waste SEI ", so the electrode can maintain a reversible capacity of 1153.2 mAh g(-1) at 1 A g(-1) after 500 cycles. This work provides important guidance for surface structural optimization of alloy-type anodes with high volume change.& nbsp; (C) 2022 Elsevier Inc. All rights reserved

Application of multispectral imaging to determine quality attributes and ripeness stage in strawberry fruit.

Multispectral imaging with 19 wavelengths in the range of 405-970 nm has been evaluated for nondestructive determination of firmness, total soluble solids (TSS) content and ripeness stage in strawberry fruit. Several analysis approaches, including partial least squares (PLS), support vector machine (SVM) and back propagation neural network (BPNN), were applied to develop theoretical models for predicting the firmness and TSS of intact strawberry fruit. Compared with PLS and SVM, BPNN considerably improved the performance of multispectral imaging for predicting firmness and total soluble solids content with the correlation coefficient (r) of 0.94 and 0.83, SEP of 0.375 and 0.573, and bias of 0.035 and 0.056, respectively. Subsequently, the ability of multispectral imaging technology to classify fruit based on ripeness stage was tested using SVM and principal component analysis-back propagation neural network (PCA-BPNN) models. The higher classification accuracy of 100% was achieved using SVM model. Moreover, the results of all these models demonstrated that the VIS parts of the spectra were the main contributor to the determination of firmness, TSS content estimation and classification of ripeness stage in strawberry fruit. These results suggest that multispectral imaging, together with suitable analysis model, is a promising technology for rapid estimation of quality attributes and classification of ripeness stage in strawberry fruit

Constructing an artificial boundary to regulate solid electrolyte interface formation and synergistically enhance stability of nano-Si anodes

Low coulombic efficiency and poor cyclic stability are two common problems for silicon anodes. Therefore, it is of great significance to improve cycling performance and initial coulombic efficiency (ICE) via rational surface engineering on nano-Si anodes. Herein, a new nano-silicon anode is obtained by straightforward constructing a multifunctional polypyrrole protective layer on the surface of silicon nanoparticles, which is further used as the inner boundary of solid electrolyte interface (SEI) film. Specifically, the Li salt decomposition reaction between the electrolyte and silicon surface is effectively inhibited under the protection of the compact artificial boundary. The transfer of Li+ for forming the SEI film is selectively slower than that of lithiation/delithiation reaction. This further reduces the amount of SEI film, leading to a high ICE of 93.2% at 0.5 A g(-1) for modified nano-Si anodes. In addition, the flexible SEI precursor combined with the high proportion of organic components in SEIs not only accommodates the volume change of nano-silicon, but also suppresses accumulation of "waste SEI ", so the electrode can maintain a reversible capacity of 1153.2 mAh g(-1) at 1 A g(-1) after 500 cycles. This work provides important guidance for surface structural optimization of alloy-type anodes with high volume change.& nbsp; (C) 2022 Elsevier Inc. All rights reserved

A rapid method for the synthesis of perovskite (ATiO(3), A = Ca, Sr, Ba) in molten chloride

This paper reports the rapid synthesis of perovskite (ATiO(3), A = Ca, Sr, Ba) via molten salt method within 10 min BaCl2 or CaCl2 was used due to their excellent solubility of O2- which enables faster mass transfer transport in the liquid phase. TiO2, ACl(2) and CaO (or BaCO3) were used as the precursors. The obtained ATiO(3) show high chemical and phase purity. Studies found that cation size in ATiO(3) plays an important role in the transformation between different perovskites. The method may provide a generalized methodology for rapid preparation of other important perovskites

Cobalt-Catalyzed Asymmetric Sequential Hydroboration/Hydrogenation of Internal Alkynes

A highly regio- and enantioselective cobalt-catalyzed hydroboration/hydrogenation of internal alkynes with HBpin and a hydrogen balloon in one pot was developed. A new type of chiral imidazoline iminopyridine (IIP) ligand was introduced for the first time in this novel and efficient strategy. This protocol used relatively simple and available starting materials with good functional group tolerance to construct more valuable chiral secondary organoboronates. The primary mechanistic studies illustrated that the cobalt-catalyzed regioselective hydroboration of alkynes did initially occur followed by HBpin-promoted and cobalt-catalyzed enantioselective hydrogenation of alkenylboronates