Investigation of Mechanical Properties and Plastic Deformation Behavior of (Ti45Cu40Zr10Ni5)100−xAlx Metallic Glasses by Nanoindentation

The effect of Al addition on mechanical properties and plastic deformation behavior of (Ti45Cu40Zr10Ni5)100−xAlx (x = 0, 2, 4, 6 and 8) amorphous alloy ribbons have been investigated by nanoindentation. The hardness and elastic modulus do not simply increase with the increase of Al content. The alloy with 8 at.% Al exhibits the highest hardness and elastic modulus. The serrations or pop-in events are strongly dependent on the loading rate and alloy composition

An Approach of Identifying and Extracting Urban Commercial Areas Using the Nighttime Lights Satellite Imagery

Urban commercial areas can reflect the spatial distribution of business activities. However, the scope of urban commercial areas cannot be easily detected by traditional methods because of difficulties in data collection. Considering the positive correlation between business scale and nighttime lighting, this paper proposes a method of urban commercial areas detection based on nighttime lights satellite imagery. First, an imagery preprocess model is proposed to correct imageries and improve efficiency of cluster analysis. Then, an exploratory spatial data analysis and hotspots clustering method is employed to detect commercial areas by geographic distribution metric with urban commercial hotspots. Furthermore, four imageries of Wuhan City and Shenyang City are selected as an example for urban commercial areas detection experiments. Finally, a comparison is made to find out the time and space factors that affect the detection results of the commercial areas. By comparing the results with the existing map data, we are convinced that the nighttime lights satellite imagery can effectively detect the urban commercial areas. The time of image acquisition and the vegetation coverage in the area are two important factors affecting the detection effect. Harsh weather conditions and high vegetation coverage are conducive to the effective implementation of this method. This approach can be integrated with traditional methods to form a fast commercial areas detection model, which can then play a role in large-scale socio-economic surveys and dynamic detection of commercial areas evolution. Hence, a conclusion can be reached that this study provides a new method for the perception of urban socio-economic activities

Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length.

Pregnancy and parturition are intricately regulated to ensure successful reproductive outcomes. However, the factors that control gestational length in humans and other anthropoid primates remain poorly defined. Here, we show the endogenous retroviral long terminal repeat transposon-like human element 1B (THE1B) selectively controls placental expression of corticotropin-releasing hormone (CRH) that, in turn, influences gestational length and birth timing. Placental expression of CRH and subsequently prolonged gestational length were found in two independent strains of transgenic mice carrying a 180-kb human bacterial artificial chromosome (BAC) DNA that contained the full length of CRH and extended flanking regions, including THE1B. Restricted deletion of THE1B silenced placental CRH expression and normalized birth timing in these transgenic lines. Furthermore, we revealed an interaction at the 5' insertion site of THE1B with distal-less homeobox 3 (DLX3), a transcription factor expressed in placenta. Together, these findings suggest that retroviral insertion of THE1B into the anthropoid primate genome may have initiated expression of CRH in placental syncytiotrophoblasts via DLX3 and that this placental CRH is sufficient to alter the timing of birth