Comparisons of Undergraduate Business Administration Education in Greater Bay Area, China

Business administration education plays an important part in supporting the development of business industry and ensuring the ongoing supply of qualifed human resources to meet the demanding industry requirements. However, the dramatic growth of the economy has not been accompanied by an adequate response from the education system. It is therefore, necessary to review the existing business administration programs. This paper will make a comparison of the current undergraduate programs in Business Administration in Guangdong-Hong Kong-Macao Greater Bay Area in the six dimensions: curriculum and instruction; strategic planning; administrative management; faculty; student achievements; and resources. Suggestions for the further development of Business Administration programs in the bay area will then be proposed

Dimensional change of wool fabrics in the process of a tumble-drying cycle

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Currently domestic tumble dryers are popularly used for drying garments; however, excessive drying and the inappropriate way of tumble agitation could waste energy and cause damage to or the dimensional change of garments. Shrinkage of wool fabrics during tumble drying causes a serious problem for wool garments. The current study investigated the shrinkage of untreated and Chlorine-Hercosett–finished wool fabrics at different drying times. Temperature of air in the tumble dryer, temperature of fabric, moisture content of fabric, and dimensional change at different drying times were measured. For the duration of the tumble drying, the rise of fabric temperature and the reduction of moisture content on the wool fabric were investigated to explore their relationship to the shrinkage of wool fabrics in the tumble-drying cycle. It was found that the tumble-drying process can be divided into different stages according to the temperature change trend of wool fabrics. The shrinkage mechanisms of the untreated and the treated fabrics were different. The dimensional change of untreated wool fabric was caused mainly by felting shrinkage during tumble drying. Chlorine-Hercosett–finished wool fabric can withstand the tumble-drying process without noticeable felting shrinkage due to the surface modification and resin coating of surface scales of wool fibers. The finding from the current research provides further understanding of the shrinkage behavior of wool fabrics during the tumble-drying process, leading to optimizing operational parameters at specific stages of a tumble-drying cycle

Regression Analysis Research on the Impact of Urbanization on Farmers’ Consumption Structure

The status of research on the impact of urbanization on farmers’ consumption structure conducted by the domestic and international scholars is described in the paper; and the argument is supported by exploration and analysis that the urbanization has exerted an influence on farmers’ consumption structure. Furthermore, by concretely exploring the related data model constructed in the research, the following achievements are made: along with the advancement of urbanization, the proportion of three categories including food and clothing in farmers’ consumption structure turns on a downward trend, while the proportion of housing, transportation, and other five categories are in an upward trend; in the farmers’ consumption expenditure, the medical and health expenditure is significantly affected by urbanization, while urbanization only has a little influence on food expenditure. On the basis of the conclusion in this paper, suggestions are put forward which include promoting the urbanization rate, creating a better condition for the development of the rural residents, improving the basic social security system and perfecting a series of policies that stimulate rural consumption including the “home appliances going to the countryside”, “mobile phones going to the countryside”, and “cars going to the countryside” etc.

Parthenolide attenuates LPS-induced activation of NF-κB in a time-dependent manner in rat myocardium.

Parthenolide (PTN), a selective nuclear factor kappa B (NF-κB) inhibitor, has been used extensively to inhibit NF-κB activation. The duration of the inhibitory effect of PTN on NF-κB in vivo remains unclear. This study was to determine whether a lipopolysaccharide (LPS) challenge 6, 12 and 24 h after the administration of PTN could activate NF-κB. Rats were devided into five groups. The rats in the PTN, PTN+LPS and DMSO groups were injected intraperitoneally with PTN or DMSO. After 6, 12 or 24 h, LPS was administered in LPS and PTN+LPS groups. The expressions of NF-κB p50, IκBα and p-IκBα were inhibited in both PTN and PTN+LPS group at end of 6 and 12 h and no effects at 24 h. In summary, myocardial NF-κB expression occurs 1 h after the administration of LPS. PTN blocks this effect given at 6 h and no inhibitory effect 24 h after administration in vivo

Genetic Control of Tumour Susceptibility in Mouse Skin Carcinogenesis

The development of tumours in mouse, as in humans, is a multiple genetic process. The molecular analysis of somatic mutations in tumours has led to the association of many oncogenes and tumour suppresser genes with a particular genetic events in tumourigenesis. However, the genes that control susceptibility to tumour formation are largely unknown. To identify these tumour susceptibility genes, genetic linkage analysis was carried out using DMBA-TPA two stage mouse skin carcinogenesis system. Linkage analysis was first carried out in the FI backcross mice (FVB/N x C57BL/6J)F1 X FVB/N). At least seven loci on chromosomes 1, 4, 6, 7, 9, 10 and 12 were found to be involved in skin tumour development. Particularly, the locus D4Mit126 was associated with papilloma, while the locus D9Mit269 with both papilloma and carcinoma. Substantial contribution to tumour susceptibility also came from locus-locus interaction. The papilloma formation was influenced by the interaction of D4Mit126-D12Mit203 and D6Mit14-D9Mit269, and the carcinoma formation was affected by the interaction of D7Mit83-D10Mit134. To confirm the loci identified in the backcross analysis, a further intensive studies on (FVB/N X C57BL/6J)F2 cross was carried out. In addition to the loci on chromosomes 4, 6, 9 and 12, seven new loci on chromosomes 3, 5, 10, 11, 15 and 16 were identified to be associated with papilloma formation. Significant contributions came from loci D6Mitl4, D10Mit248 and D12Mit68, as well as the interactions of D11Mit99- D3Mit49, D10Mit248-D16Mit51 and D16Mit64-D15Mit189. The loci linked to carcinoma formation were found at loci D3Mit46, D8Mit211 and D12Nds2. The results of these two linkage studies demonstrate that the susceptibility to skin tumour development is influenced by multiple genetic loci and their interactions. The fact, that the loci identified to be associated with papilloma and carcinoma are mostly different, implies that the development of papillomas and carcinomas is under different genetic controls

Preparation, evaluation, and pharmacokinetics in beagle dogs of a taste-masked flunixin meglumine orally disintegrating tablet prepared using hot-melt extrusion technology and D-optimal mixture design

Flunixin meglumine (FM) is a nonsteroidal anti-inflammatory drug limited by irritation of the respiratory tract and mucosa in veterinary tissue. This study aimed to develop a taste-masked FM solid dispersion (SD) by hot-melt extrusion (HME) and formulate an orally disintegrating tablet (ODT) with selected excipients by direct compression. Eudragit® E PO was chosen as the matrix, and HME parameters were optimized: extrusion temperature, 135℃; screw speed, 100 rpm; and drug loading, 20%. Characterization techniques proved that FM was rendered amorphous in the HME extrudate. In vitro dissolution studies showed that FM SD released significantly slower than the corresponding physical mixture in artificial saliva. Excipients were selected based on compression formability, disintegration, and solubility. A D-optimal mixture design was used to optimize the composition: 25% FM SD, 18.75% microcrystalline cellulose, 52.5% mannitol, 3.75% low-substituted hydroxypropyl cellulose, and 1% magnesium stearate. Taste-masked FM ODT had a tensile strength of 0.7 ± 0.01 MPa and a disintegration time of 17.6 ± 0.1 s. E-tongue and E-nose analysis showed that FM ODT had a better taste-masked effect than commercial granules. Finally, a pharmacokinetic study proved that the main pharmacokinetic parameters of FM ODT were not significantly different from those of commercial granules, which indicated that these formulations had similar pharmacokinetic behaviours in beagles

PII: S0962-8924(01)02127-4

The mouse is an ideal model system for studying the molecular mechanisms underlying the pathogenesis of human cancer. The generation of transgenic and gene-knockout mice has been instrumental in determining the role of major determinants in this process, such as oncogenes and tumor-suppressor genes. In the past few years, modeling cancer in the mouse has increased in its complexity, allowing in vivo dissection of the fundamental concepts underlying cooperative oncogenesis in various tumor types. In this review, we discuss how this transition has been facilitated, providing relevant examples. We also review how, in the post-genome era, novel methodologies will further accelerate the study of multi-step tumorigenesis in the mouse

An optical clock based on a topological attractor in the polariton superfluid dynamics

We propose an optical polariton clock based on the topologically protected persistent oscillatory dynamics of a polariton superfluid, which is excited non-resonantly by a super-Gaussian laser beam in a semiconductor microcavity containing an external C-shape potential. The persistent oscillations, characterised by a topological attractor, are based on the dynamical behavior of small Josephson vortices rotating around the edge of the core of the central vortex. The clock demonstrates a remarkable stability towards perturbations and may be tuned by the pump laser intensity to two different frequency ranges: 20.16{\pm}0.14 GHz and 48.4{\pm}1.2 GHz. This clock generator is bistable due to the chirality of the vortex