Modelo de educación de la inteligencia colectiva

The research carried out is part of the field of study of Collective Intelligence (CI) with the use of Information and Communication Technologies (ICT) in Higher Education. The heart of this research was focused on the study, design and construction of electronic tools according to the paradigms of CI, to be applied in Higher Education. As an instrument for the implementation of these tools, an educational model with a collective work approach was designed. The research strategy used was Design-Based Research (DBR), because it investigates a phenomenon in its real context, iterative and incremental, and it is especially recommended for the field of education. DBR in each experimental cycle updates literature, model and tools. Empirical studies were conducted in four universities and fields of study in Latin America and Europe. The refinements demanded by the research strategy provided the scientific and empirical evidence to design ICT tools that meet the requirements of CI. In addition, the results indicate that the educational model and the tools have generated a positive perception in teachers and students about the effects on the teaching-learning process. Based on this fact, the experimental cycles present significant contributions to the research carried out around the CI with ICT tools in Higher Education.La investigación realizada se enmarca en el campo de estudio de la Inteligencia Colectiva (IC) con el uso de las Tecnologías de la Información y la Comunicaciones (TIC) en la Educación Superior. El corazón de ésta investigación estuvo enfocada en el estudio, diseño y construcción de herramientas electrónicas acorde a los paradigmas de IC, para ser aplicadas en la Educación Superior. Como vía de instrumentación de dichas herramientas, se diseñó un modelo educativo con enfoque de trabajo colectivo. La estrategia de investigación que se utilizó fue la Investigación Basada en el Diseño (DBR), porque investiga un fenómeno en su contexto real, es iterativa e incremental, y está especialmente recomendada para el ámbito de la educación.DBR en cada ciclo experimental actualiza literatura, modelo y herramientas. Los estudios empíricos se realizaron en cuatro universidades y campos de estudio en Hispanoamérica y Europa. Los múltiples refinamientos exigidos por la estrategia de investigación, proporcionaron la evidencia científica y empírica para diseñar herramientas TIC que cumplan con los requisitos de IC. Además, los resultados indican que el modelo educativo y las herramientas han generado una percepción positiva en docentes y estudiantes sobre los efectos en el proceso de enseñanza-aprendizaje. Basados en este hecho, los ciclos experimentales presentan aportes significativos a las investigaciones que se realizan en torno a la IC con herramientas TIC en la Educación Superior

Additional file 1: of Experiences of primary care physicians and staff following lean workflow redesign

Respondent Characteristics When Assessing Changes in Physician Experiences After Workflow Redesigns. This file details all the respondent characteristics that were adjusted for in the analysis of physician work experiences shown in Table 2. (DOCX 601 kb

Additional file 2: of Experiences of primary care physicians and staff following lean workflow redesign

Respondent Characteristics When Assessing Changes in Non-physician Staff Experiences After Workflow Redesigns. This file details all the respondent characteristics that were adjusted for in the analysis of non-physician staff work experiences shown in Table 3. (DOCX 562 kb

DataSheet2_Bibliometric and visualized analysis of the application of nanotechnology in glioma.PDF

Background: Glioma is the most prevalent malignant tumor in the central nervous system (CNS). Due to its highly invasive characteristics and the existence of the blood–brain barrier (BBB), the early diagnosis and treatment of glioma remains a major challenge in cancer. With the flourishing development of nanotechnology, targeted nano-therapy for glioma has become a hot topic of current research by using the characteristics of nanoparticles (NPs), such as it is easier to pass the blood–brain barrier, degradable, and aids controllable release of drugs in the brain. The purpose of this study is to visualize the scientific achievements and research trends of the application of nanotechnology in glioma.Methods: We searched the literature related to glioma nanotechnology on the Web of Science (WOS). The bibliometric and visual analysis was performed mainly using CiteSpace, VOSviewer, and R software, for countries/regions, authors, journals, references, and keywords associated with the field.Results: A total of 3,290 publications from 2012 to June 2022 were searched, and 2,041 works of literature were finally obtained according to the search criteria, the number of publications increasing year by year, with an average growth rate (AGR) of 15.22% from 2012 to 2021. China published 694 (20.99%), followed by the United States (480, 20.70%). The institution with the highest number of publications is Fudan Univ (111, 13.16%), and 80% of the top ten institutions belong to China. HUILE GAO (30) and XINGUO JIANG (30) both published the largest number of research studies. STUPP R (412) was the most cited author, followed by GAO HL (224). The degree of collaboration (DC) among countries/regions, research institutions, and authors is 23.37%, 86.23%, and 99.22%, respectively. International Journal of Nanomedicine published the largest number of publications (81), followed by Biomaterials (73). Biomaterials (1,420) was the most cited journal, followed by J Control Release (1,300). The high frequency of keywords was drug delivery (487), followed by nanoparticle (450), which indicates that nanoparticles (NPs) as a carrier for drug delivery is a hot topic of current research and a direction of continuous development.Conclusion: In recent years, nanotechnology has attracted much attention in the medical field. Cooperation and communication between countries/regions and institutions need to be strengthened in future research to promote the development of nanomedicine. Nanotherapeutic drug delivery systems (NDDS) can enhance drug penetration and retention in tumor tissues, improve drug targeting, and reduce the toxic side effects of drugs, which has great potential for the treatment of glioma and has become the focus of current research and future research trends in the treatment of glioma.</p

DataSheet1_Bibliometric and visualized analysis of the application of nanotechnology in glioma.PDF

Background: Glioma is the most prevalent malignant tumor in the central nervous system (CNS). Due to its highly invasive characteristics and the existence of the blood–brain barrier (BBB), the early diagnosis and treatment of glioma remains a major challenge in cancer. With the flourishing development of nanotechnology, targeted nano-therapy for glioma has become a hot topic of current research by using the characteristics of nanoparticles (NPs), such as it is easier to pass the blood–brain barrier, degradable, and aids controllable release of drugs in the brain. The purpose of this study is to visualize the scientific achievements and research trends of the application of nanotechnology in glioma.Methods: We searched the literature related to glioma nanotechnology on the Web of Science (WOS). The bibliometric and visual analysis was performed mainly using CiteSpace, VOSviewer, and R software, for countries/regions, authors, journals, references, and keywords associated with the field.Results: A total of 3,290 publications from 2012 to June 2022 were searched, and 2,041 works of literature were finally obtained according to the search criteria, the number of publications increasing year by year, with an average growth rate (AGR) of 15.22% from 2012 to 2021. China published 694 (20.99%), followed by the United States (480, 20.70%). The institution with the highest number of publications is Fudan Univ (111, 13.16%), and 80% of the top ten institutions belong to China. HUILE GAO (30) and XINGUO JIANG (30) both published the largest number of research studies. STUPP R (412) was the most cited author, followed by GAO HL (224). The degree of collaboration (DC) among countries/regions, research institutions, and authors is 23.37%, 86.23%, and 99.22%, respectively. International Journal of Nanomedicine published the largest number of publications (81), followed by Biomaterials (73). Biomaterials (1,420) was the most cited journal, followed by J Control Release (1,300). The high frequency of keywords was drug delivery (487), followed by nanoparticle (450), which indicates that nanoparticles (NPs) as a carrier for drug delivery is a hot topic of current research and a direction of continuous development.Conclusion: In recent years, nanotechnology has attracted much attention in the medical field. Cooperation and communication between countries/regions and institutions need to be strengthened in future research to promote the development of nanomedicine. Nanotherapeutic drug delivery systems (NDDS) can enhance drug penetration and retention in tumor tissues, improve drug targeting, and reduce the toxic side effects of drugs, which has great potential for the treatment of glioma and has become the focus of current research and future research trends in the treatment of glioma.</p

Table_1_Research on application of radiomics in glioma: a bibliometric and visual analysis.pdf

BackgroundWith the continuous development of medical imaging informatics technology, radiomics has become a new and evolving field in medical applications. Radiomics aims to be an aid to support clinical decision making by extracting quantitative features from medical images and has a very wide range of applications. The purpose of this study was to perform a bibliometric and visual analysis of scientific results and research trends in the research application of radiomics in glioma.MethodsWe searched the Web of Science Core Collection (WOScc) for publications related to glioma radiomics. A bibliometric and visual analysis of online publications in this field related to countries/regions, authors, journals, references and keywords was performed using CiteSpace and R software.ResultsA total of 587 relevant literature published from 2012 to September 2022 were retrieved in WOScc, and finally a total of 484 publications were obtained according to the filtering criteria, including 393 (81.20%) articles and 91 (18.80%) reviews. The number of relevant publications increases year by year. The highest number of publications was from the USA (171 articles, 35.33%) and China (170 articles, 35.12%). The research institution with the highest number of publications was Chinese Acad Sci (24), followed by Univ Penn (22) and Fudan Univ (21). WANG Y (27) had the most publications, followed by LI Y (22), and WANG J (20). Among the 555 co-cited authors, LOUIS DN (207) and KICKINGEREDER P (207) were the most cited authors. FRONTIERS IN ONCOLOGY (42) was the most published journal and NEURO-ONCOLOGY (412) was the most co-cited journal. The most frequent keywords in all publications included glioblastoma (187), survival (136), classification (131), magnetic resonance imaging (113), machine learning (100), tumor (82), and feature (79), central nervous system (66), IDH (57), and radiomics (55). Cluster analysis was performed on the basis of keyword co-occurrence, and a total of 16 clusters were formed, indicating that these directions are the current hotspots of radiomics research applications in glioma and may be the future directions of continuous development.ConclusionIn the past decade, radiomics has received much attention in the medical field and has been widely used in clinical research applications. Cooperation and communication between countries/regions need to be enhanced in future research to promote the development of radiomics in the field of medicine. In addition, the application of radiomics has improved the accuracy of pre-treatment diagnosis, efficacy prediction and prognosis assessment of glioma and helped to promote the development into precision medicine, the future still faces many challenges.</p

Single trial time-course (see Fig. 1 in the study of Fliessbach et al., 2007).

<p>Single trial time-course (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082534#pone-0082534-g001" target="_blank">Fig. 1</a> in the study of Fliessbach et al., 2007).</p

(A) Mean of the satisfaction judgment of the fair distribution conditions; (B) Mean of the satisfaction judgment of the unfair distribution conditions.

<p>(A) Mean of the satisfaction judgment of the fair distribution conditions; (B) Mean of the satisfaction judgment of the unfair distribution conditions.</p

Effects observed in the brain in response to unfair distribution conditions: (A) Activation in the ventral striatum and the mean percentage signal change for the unfair distribution conditions in the ventral striatum; (B) Activation in the VMPFC and the mean percentage signal change for the unfair distribution conditions in the VMPFC; (C) Activation in the DPFC and the mean percentage signal change for the unfair distribution conditions in the DPFC.

<p>Effects observed in the brain in response to unfair distribution conditions: (A) Activation in the ventral striatum and the mean percentage signal change for the unfair distribution conditions in the ventral striatum; (B) Activation in the VMPFC and the mean percentage signal change for the unfair distribution conditions in the VMPFC; (C) Activation in the DPFC and the mean percentage signal change for the unfair distribution conditions in the DPFC.</p

Long-Term Effects of Acute Stress on the Prefrontal-Limbic System in the Healthy Adult

<div><p>Most people are exposed to at least one traumatic event during the course of their lives, but large numbers of people do not develop posttraumatic stress disorders. Although previous studies have shown that repeated and chronic stress change the brain’s structure and function, few studies have focused on the long-term effects of acute stressful exposure in a nonclinical sample, especially the morphology and functional connectivity changes in brain regions implicated in emotional reactivity and emotion regulation. Forty-one months after the 5/12 Wenchuan earthquake, we investigated the effects of trauma exposure on the structure and functional connectivity of the brains of trauma-exposed healthy individuals compared with healthy controls matched for age, sex, and education. We then used machine-learning algorithms with the brain structural features to distinguish between the two groups at an individual level. In the trauma-exposed healthy individuals, our results showed greater gray matter density in prefrontal-limbic brain systems, including the dorsal anterior cingulate cortex, medial prefrontal cortex, amygdala and hippocampus, than in the controls. Further analysis showed stronger amygdala-hippocampus functional connectivity in the trauma-exposed healthy compared to the controls. Our findings revealed that survival of traumatic experiences, without developing PTSD, was associated with greater gray matter density in the prefrontal-limbic systems related to emotional regulation.</p></div