5,208 research outputs found
Strong optical force induced by morphology dependent resonances
We consider the resonant optical force acting on a pair of transparent
microspheres by the excitation of the Morphology Dependent Resonance (MDR). The
bonding and anti-bonding modes of the MDR correspond to strong attractions and
repulsions respectively. The dependence of the force on separation and the role
of absorption are discussed. At resonance, the force can be enhanced by orders
of magnitude so that it will dominate over other relevant forces. We find that
a stable binding configuration can be induced by the resonant optical force.Comment: 4 pages, 4 figure
Nano- and Micro-materials in the Treatment of Internal Bleeding and Uncontrolled Haemorrhage
Internal bleeding is defined as the loss of blood that occurs inside of a body cavity. After a traumatic injury, haemorrhage accounts for over 35% of pre-hospital deaths and 40% of deaths within the first 24hours. Coagulopathy, a disorder in which the blood is not able to properly form clots, typically develops after traumatic injury and results in a higher rate of mortality. The current methods to treat internal bleeding and coagulopathy are inadequate due to the requirement of extensive medical equipment that is typically not available at the site of injury. To discover a potential route for future research, several current and novel treatment methods have been reviewed and analysed. The aim of investigating different potential treatment options is to expand available knowledge, while also call attention to the importance of research in the field of treatment for internal bleeding and haemorrhage due to trauma
Dynamics of quantum dissipation systems interacting with Fermion and Boson grand canonical bath ensembles: Hierarchical equations of motion approach
A hierarchical equations of motion formalism for a quantum dissipation system
in a grand canonical bath ensemble surrounding is constructed, on the basis of
the calculus-on-path-integral algorithm, together with the parametrization of
arbitrary non-Markovin bath that satisfies fluctuation-dissipation theorem. The
influence functionals for both the Fermion or Boson bath interaction are found
to be of the same path-integral expression as the canonical bath, assuming they
all satisfy the Gaussian statistics. However, the equation of motion formalism
are different, due to the fluctuation-dissipation theories that are distinct
and used explicitly. The implications of the present work to quantum transport
through molecular wires and electron transfer in complex molecular systems are
discussed.Comment: 12page
Fucosylation inhibitor development for producing afucosylated antibodies
Please click Additional Files below to see the full abstract
Shape complexity and fractality of fracture surfaces of swelled isotactic polypropylene with supercritical carbon dioxide
We have investigated the fractal characteristics and shape complexity of the
fracture surfaces of swelled isotactic polypropylene Y1600 in supercritical
carbon dioxide fluid through the consideration of the statistics of the islands
in binary SEM images. The distributions of area , perimeter , and shape
complexity follow power laws , , and , with the scaling ranges spanning
over two decades. The perimeter and shape complexity scale respectively as
and in two scaling regions delimited by . The fractal dimension and shape complexity increase when the temperature
decreases. In addition, the relationships among different power-law scaling
exponents , , , , and have been derived analytically,
assuming that , , and follow power-law distributions.Comment: RevTex, 6 pages including 7 eps figure
Egorov's theorem for transversally elliptic operators on foliated manifolds and noncommutative geodesic flow
The main result of the paper is Egorov's theorem for transversally elliptic
operators on compact foliated manifolds. This theorem is applied to describe
the noncommutative geodesic flow in noncommutative geometry of Riemannian
foliations.Comment: 23 pages, no figures. Completely revised and improved version of
dg-ga/970301
The use of cell and larval assays to identify target genes for RNA interference-meditated control of the Australian sheep blowfly (Lucilia cuprina)
BACKGROUND Flystrike, primarily caused by Lucilia cuprina, is a major health and welfare issue for sheep wool industries. Current chemical-based controls can have limited effectiveness due to the emergence of resistance in the parasite. RNA interference (RNAi), which uses double-stranded RNA (dsRNA) as a trigger molecule, has been successfully investigated for the development of innovative pest control strategies. Although RNAi offers great potential, the efficient identification, selection of target genes and delivery of dsRNA represent challenges to be overcome for the successful application of RNAi for control of L. cuprina. RESULTS A primary L. cuprina (blowfly) embryo cell line (BFEC) was established and confirmed as being derived from L. cuprina eggs by PCR and amplicon sequencing. The BFECs were successfully transfected with plasmids and messenger RNA (mRNA) expressing fluorescent reporter proteins and dsRNA using lipid-based transfection reagents. The transfection of dsRNA into BEFC in this study suggested decreased mRNA levels of target gene expression, which suggested RNAi-mediated knockdown. Three of the dsRNAs identified in this study resulted in reductions of in target gene mRNA levels in BFEC and loss of biological fitness by L. cuprina larvae in a feeding bioassay. CONCLUSION This study confirms that the novel BFEC cell line can be used to improve the efficacy of dsRNA-mediated screening to accelerate the identification of potential target genes in the development of RNAi mediated control approaches for L. cuprina. The research models established in this study are encouraging with respect to the use of RNAi as a blowfly control method, however further improvement and validation are required for field applicationsnot prefect, and could be ongoing developing. © 2024 Society of Chemical Industry
- …