5 research outputs found

    The Effect of School Funding on Standardized Test Scores

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    Most schools in America use standardized tests to determine how students do on average based on their peers and what they have been studying on school. These scores can also reflect a students comprehension on the material taught in class. The quality of the education provided can also be a factor that greatly influences a students’ performance on these standardized tests. The funding of a school is a major factor that influences the quality of education a school is able to provide. As a group, we analyzed data sets that analyzed the funding and standardized test scores of different schools in Illinois. In doing so, a better understanding between a school’s financial status and their standardized test scores was found, and this knowledge can be applied in future considerations about funding to improve the overall quality of education in schools in America

    EL COLOR DE LA IRA

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    https://digitalcommons.imsa.edu/spanish_books/1002/thumbnail.jp

    Take Action Campaign #4: Proyecto

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    https://digitalcommons.imsa.edu/spanish_v/1004/thumbnail.jp

    Maria del Refugio Corral

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    Illustration: Monika Narain / Narration: Brandon Smith, Archan Das, Monika Narain, Hannah Xu and Krisha Patelhttps://digitalcommons.imsa.edu/spanish_v/1000/thumbnail.jp

    A Search for Inhibitors of HGXPRT Using 3D Molecular Docking

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    Malaria is a bloodborne disease primarily spread by mosquitoes. In 2019, there were an estimated 229 million cases of malaria worldwide, many of which were in third-world countries. Even though there are drugs that can combat malaria, they are not accessible to most consumers in need because of their high cost and, even if a consumer can access these drugs, they have low efficacy rates. HGXPRT is a purine salvage enzyme synthesized by malaria-causing parasites that is essential for their survival. Studies conducted in the past have concluded that neutralizing HGXPRT is an essential part of finding an affordable cure for malaria. This study focused on introducing different molecular compounds to HGXPRT to find a potential drug to combat malaria. Drug-like compounds from the Medicines for Malaria Venture’s Malaria Box were molecularly docked with the structure 3OZF to determine the potential for binding. Factors considered were Gibbs free energy, FullFitness, and positioning of the ligand relative to the 3OZF molecule compared to the original ligand, hypoxanthine. The goal of this study was to identify and prioritize specific compounds for further testing as potential drugs to combat malaria and to provide the scientific community with this data
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