1,050 research outputs found
Even cycles and perfect matchings in claw-free plane graphs
Lov{\'a}sz showed that a matching covered graph has an ear decomposition
starting with an arbitrary edge of . Let be a graph which has a perfect
matching. We call cycle-nice if for each even cycle of ,
has a perfect matching. If is a cycle-nice matching covered graph, then
has ear decompositions starting with an arbitrary even cycle of . In this
paper, we characterize cycle-nice claw-free plane graphs. We show that the only
cycle-nice simple 3-connected claw-free plane graphs are , and
. Furthermore, every cycle-nice 2-connected claw-free plane
graph can be obtained from a graph in the family by a sequence of
three types of operations, where consists of even cycles, a diamond,
, and .Comment: 12 page
Biosafey evaluation and anti-oxidative effects of ceria nanoparticles in vitro
Ceria nanoparticles are well known as high-performance catalysts due to the presence of mixed valence states of Ce3+ and Ce4+, and the presence of oxygen vacancies. Ceria nanoparticles are also potent free-radical scavengers due to its SOD mimics, catalase mimics and oxidase mimics. It is speculated that nanoceria would promote cell survival under conditions of oxidative stress due to its selective antioxidant properties. The antioxidant properties can be affected by the physicochemical properties of the materials and the target cells species. Therefore, in the present study, we evaluate the biosafety and protective effect of two different sizes of ceria nanoparticles in human umbilical vein endothelial cells (HUVECS) and human bronchial epithelial cells (HBE), as they are the primary routes of human exposure to nanoparticles through inhalation and injection. Based on the results of cell viability assay and cell membrane integrity assay, we found that ceria nanoparticles of both sizes are biocompatible to both HUVECS and HBE cells, though ceria nanoparticles have a slightly interference in the intracellular redox balance. In addition, ceria nanoparticles showed protective effect on the cell viability of both cells under oxidative stress. Detailed studies on the intracellular molecular mechanisms for the anti-oxidative effects will be studies to understand the nanoparticles-cell interactions. These results obtained in vitro may provide insights for real biomedical applications and risk assessment of ceria nanoparticle
A Novelty Method for Identifying Risk Factors of Sudden Food Safety Event
Food is the basic material basis for human survival. Sudden food safety event risks mainly derive from accidental or natural food safety risks, poor food storage environments, and inefficient government regulation policies. The factor identification of sudden food safety risks is the key to controlling such risks. Therefore, the efficient and scientific identification of risk sources and types will be very important in managing sudden food safety risks. In this study, 16 sudden food safety event risk factors were identified through a literature review, and their interactive relationships were clarified using an interpretive structural model (ISM). Then, the weights of influencing factors were calculated through the analytic hierarchy process (AHP), and the combined weight of indices was determined. Results show that the 16 sudden food safety event risk factors can be divided into four levels. The quality standard for food safety (S5) and food storage (S14) is at the bottom layer of risks of sudden food safety events (the first-layer index weight is 36.899%). The judgment matrices at the four levels passed the consistency check. The influence weight of the factor "whether it contains transgenic raw materials" (S9) ranks second (the total weight is 18.151%). This index system for sudden food safety event risk factors is highly effective, with good operability for managing sudden food safety event risks. The obtained conclusions are important reference values for identifying the factors influencing food safety risk management, determining the emphasis of food safety supervision, realizing food risk prevention and control, and strengthening and guaranteeing the food safety level
Bigeye tuna fishing ground in relation to thermocline in the Western and Central Pacific Ocean using Argo data
444-451The relationship beween thermocline and bigeye tuna (Thunnus obesus) fishing grounds in the Western and Central Pacific Ocean was evaluated by Argo data and monthly CPUE (catch per unit effort). The generalized additive model indicated evidence of nonlinear relationships between CPUE and six thermocline characteristics. The results suggested that the fishing grounds distributed where the upper boundary temperature was about 26 ºC and the upper boundary depth values between 70 and 100 m. The fishing grounds located between the two high value shapes of the lower boundary depth of thermocline, if the depth was >300 or <150 m, the CPUE tended to be low. The lower boundary temperature of the thermocline in the fishing grounds was lower than 13 ºC. Conversely, if the temperature was higher than 17 ºC, the hooking rates were very low. The strongest relationship between CPUE with thermocline thickness and thermocline strength was approximately at 60 m and 0.1 ºC/m. The optimum ranges for the upper boundary thermocline temperature and depth and the lower boundary thermocline temperature and depth, thermocline thickness and thermocline strength were between 26-29 ºC, 70-110 m, 11-13 ºC, 200-280 m, and 0.01-0.15 ºC/m, 60-80 m, respectively
The Construction of a Clinical Decision Support System Based on Knowledge Base
Part 7: e-Health, the New Frontier of Service Science InnovationInternational audienceBased on a review of domestic and foreign research, application status, classification, composition, and the main problem of a clinical decision support system, this paper proposed a CDSS mode based on a knowledge base. On KB-CDSS mode, this paper discussed the architecture, principle, process, construction of the knowledge base, system design, and application value, then introduced the application WanFang Data Clinical Diagnosis and Treatment Knowledge Base
Methyl 3,4-O-isopropylidene-2-O-[(methylsulfanyl)thiocarbonyl]-β-l-arabinoside
In the title compound, C11H18O5S2, the six- and five-membered rings adopt a chair and an approximately planar conformation, respectively
Association between Functional Polymorphisms of Foxp3 Gene and the Occurrence of Unexplained Recurrent Spontaneous Abortion in a Chinese Han Population
Unexplained recurrent spontaneous abortion (URSA) is an alloimmune disease associated with the failure of fetal-maternal immunologic tolerance in which the regulatory T lymphocytes (Treg) play a pivotal role. It is well known that Forkhead box P3 (Foxp3) is a crucial regulatory factor for the development and function of Treg cells. It has also been established that deficiency of the Foxp3 gene suppresses the regulatory function of Treg cells. To determine if functional polymorphisms at the Foxp3 loci are associated with URSA in humans, we genotyped four common polymorphisms of Foxp3 gene in 146 unrelated URSA patients and 112 healthy women. The results showed that rs3761548A/C and rs2232365A/G polymorphisms were significantly associated with URSA. Additionally, we found that the allelic distribution of rs5902434 del/ATT in URSA group was slightly different from that in the control group. We conclude that functional polymorphisms of the Foxp3 gene may confer an important susceptibility to URSA in the Chinese Han population, probably by altering Foxp3 function and/or its expression
Crystal Structure Manipulation of the Exchange Bias in an Antiferromagnetic Film
Exchange bias is one of the most extensively studied phenomena in magnetism,
since it exerts a unidirectional anisotropy to a ferromagnet (FM) when coupled
to an antiferromagnet (AFM) and the control of the exchange bias is therefore
very important for technological applications, such as magnetic random access
memory and giant magnetoresistance sensors. In this letter, we report the
crystal structure manipulation of the exchange bias in epitaxial hcp Cr2O3
films. By epitaxially growing twined (10-10) oriented Cr2O3 thin films, of
which the c axis and spins of the Cr atoms lie in the film plane, we
demonstrate that the exchange bias between Cr2O3 and an adjacent permalloy
layer is tuned to in-plane from out-of-plane that has been observed in (0001)
oriented Cr2O3 films. This is owing to the collinear exchange coupling between
the spins of the Cr atoms and the adjacent FM layer. Such a highly anisotropic
exchange bias phenomenon is not possible in polycrystalline films.Comment: To be published in Scientific Reports, 12 pages, 6 figure
Effects of oridonin nanosuspension on cell proliferation and apoptosis of human prostatic carcinoma PC-3 cell line
This study aims to investigate the inhibitory effects of oridonin nanosuspension on human prostatic carcinoma PC-3 cell line in vitro. The PC-3 cells were incubated with increasing concentrations of oridonin solution and nanosuspensions for 12 hours, 24 hours, and 36 hours. MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay was performed to measure cellular viability and investigate the effect of oridonin on cell growth of PC-3. Annexin V-FITC/PI staining method was used to determine the effect of oridonin by fluorescence microscope and flow cytometry, respectively. Nanosuspension on early apoptosis of PC-3 cells was also evaluated. Oridonin significantly inhibited the growth of PC-3 cells after 12 hours, 24 hours, and 36 hours of treatment in a dose-dependent manner (P < 0.05). Compared with the same concentration of oridonin solution, oridonin nanosuspension enhanced the inhibition ratio of proliferation. The observation of propidium iodide fluorescence staining confirmed the MTT assay results. The cell proportion of PC-3 at the G2/M phase in the nanosuspension treatment group was upregulated compared with that of the control and oridonin solution groups. Both oridonin solution and nanosuspension promoted the early apoptosis of PC-3 cells. Furthermore, while improving the ratio of early apoptosis, oridonin nanosuspensions also enhanced growth suppression, and induced apoptosis of PC-3 cells. This shows great potential in the treatment of androgen-independent carcinoma of prostate by oridonin nanosuspensions
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