Validity of the “Streitberger” Needle in a Chinese Population with Acupuncture: A Randomized, Single-Blinded, and Crossover Pilot Study

We studied the validity of a “Streitberger” needle as a valid approach in a Chinese population with experience of acupuncture. Volunteers were recruited from students of the School of Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine. Sixty students receiving education in acupuncture theory and experience in practical acupuncture were tested in study determining whether needling with the placebo needle felt any different from conventional acupuncture. Outcomes included measures of penetration sensation, VAS ratings, and Deqi sensation questionnaire. As a result, needle penetration, VAS ratings for either needle and Deqi sensation were not significantly different between two kinds of needles. Our findings show that the use of “Streitberger” needle is credible in a Chinese population with acupuncture experience

Deep Descriptor Transforming for Image Co-Localization

Reusable model design becomes desirable with the rapid expansion of machine learning applications. In this paper, we focus on the reusability of pre-trained deep convolutional models. Specifically, different from treating pre-trained models as feature extractors, we reveal more treasures beneath convolutional layers, i.e., the convolutional activations could act as a detector for the common object in the image co-localization problem. We propose a simple but effective method, named Deep Descriptor Transforming (DDT), for evaluating the correlations of descriptors and then obtaining the category-consistent regions, which can accurately locate the common object in a set of images. Empirical studies validate the effectiveness of the proposed DDT method. On benchmark image co-localization datasets, DDT consistently outperforms existing state-of-the-art methods by a large margin. Moreover, DDT also demonstrates good generalization ability for unseen categories and robustness for dealing with noisy data.Comment: Accepted by IJCAI 201

(meso-5,7,7,12,14,14-Hexamethyl-1,4,8,11-tetra­azacyclo­tetra­deca-4,11-diene)nickel(II) bis­[O,O′-bis(4-methyl­phen­yl) dithio­phosphate]

In the title compound, [Ni(C16H32N4)](C14H14O2PS2)2 or [Ni(trans[14]dien)][S2P(OC6H4Me-4)2]2, where trans[14]dien is meso-5,7,7,12,14,14-hexa­methyl-1,4,8,11-tetra­azacyclo­tetra­deca-4,11-diene, the NiII ion lies across a centre of inversion and is four-coordinated in a relatively undistorted square-planar arrangement by the four N atoms of the macrocyclic ligand trans[14]dien. The two O,O′-di(4-methyl­phen­yl)dithio­phos­phates act as counter-ions to balance the charge. Important geometric data include Ni—N = 1.9135 (16) and 1.9364 (15) Å

Composition and Morphology of Nanocrystals in Urines of Lithogenic Patients and Healthy Persons

The composition and morphology of nanocrystals in urines of healthy persons and lithogenic patients were comparatively investigated by means of X-ray diffraction (XRD) and transmission electron microscopy (TEM). It was shown that the main composition of urinary nanocrystals in healthy persons were calcium oxalate dihydrate (COD), uric acid, and ammonium magnesium phosphate (struvite). However, the main compositions of urinary nanocrystals in lithogenic patients were struvite, β-tricalcium phosphate, uric acid, COD, and calcium oxalate monohydrate (COM). According to the XRD data, the size of nanocrystals was calculated to be 23∼72 nm in healthy urine and 12∼118 nm in lithogenic urine by Scherer formula. TEM results showed that the nanocrystals in healthy urine were dispersive and uniform with a mean size of about 38 nm. In contrast, the nanocrystals in lithogenic urine were much aggregated with a mean size of about 55 nm. The results in this work indicated that the urinary stone formation may be prevented by diminishing the aggregation and the size differentiation of urinary nanocrystals by physical or chemical methods

Bis(O,O′-diphenethyl dithio­phosphato-κ2 S,S′)bis­(4-methyl­pyridine-κN)nickel(II)

The title complex, [Ni(C16H18O2PS2)2(C6H7N)2], exhibits a roughly octa­hedral coordination geometry. The NiII atom lies on an inversion centre and is coordinated by four S atoms of O,O′-diphenethyl dithio­phosphate mol­ecules and two N atoms of 4-methyl­pyridine mol­ecules. Important geometric data include Ni—N = 2.100 (3) Å, and Ni—S = 2.5101 (10) and 2.4772 (11) Å

{N′-[(E)-1-(5-Bromo-2-oxidophen­yl)ethyl­idene]-4-chloro­benzohydrazidato}pyridinenickel(II)

The title complex, [Ni(C15H10BrClN2O2)(C5H5N)], displays a square-planar coordination geometry around the NiII ion, formed by the tridentate hydrazone and monodentate pyridine ligands, with the N atoms in a trans arrangement about the Ni center

(meso-5,5,7,12,12,14-Hexamethyl-1,4,8,11-tetra­azacyclo­tetra­deca­ne)nickel(II) bis­(O,O′-dibenzyl dithio­phosphate)

In the title salt-type 1:2 adduct, [Ni(C16H36N4)](C14H14O2PS2)2 or [Ni(tet-a)][S2P(OCH2Ph)2]2, where tet-a is meso-5,5,7,12,12,14-hexa­methyl-1,4,8,11-tetra­azacyclo­tetra­decane, the [Ni(tet-a)]2+ complex cation exhibits a relatively undistorted square-planar geometry about the Ni atom, which lies on an inversion centre and is coordinated by four macrocyclic N atoms. The two O,O′-bis­(2-phenyl­meth­yl) dithio­phosphate anions act as counter-ions to balance the charge and they inter­act with the complex through N—H⋯S hydrogen bonds. Important geometric data include Ni—N distances of 1.958 (3) and 1.963 (3) Å

Research on the Pricing of Shared Ownership Housing

To a great extent, the abnormal phenomena of profit making in speculation houses will disappear and the rigid housing demand of ordinary families will be resolved by shared ownership housing. Starting from the consumption structure of the target group of the shared ownership housing, this paper makes an in-depth analysis of the pilot cities that have implemented the shared ownership housing through literature review and data survey, empirically analyses the deviation degree of house rent and the unbalanced situation of residents' housing affordability, and studies the rent of the shared ownership housing and the unbalanced situation of residents' housing affordability through panel data model. Through the comprehensive index of housing affordability to find out the best proportion of the rent of shared ownership housing in the monthly income of young workers aged 20-35, and then get the monthly rent, give relevant feasible suggestions. The research shows that government departments should implement the common property right housing from the aspects of reducing land transferring fees and taxes, strengthening the qualification examination mechanism and so on

Pharmacokinetic Interaction between Magnolol and Piperine in Rats

Purpose: To investigate the pharmacokinetic mechanism of interaction between magnolol and piperine when co-administered to rats.Methods: The rats were divided into five groups as follows: magnolol group (625 mg/kg); low dose of piperine group (20 mg/kg); high dose of piperine group (40 mg/kg); low dose of piperine + magnolol group; or high dose of piperine + magnolol group. Plasma samples were collected at regular time intervals after administration of a single dose of magnolol (625 mg/kg, p.o.) alone or piperine (20 or 40 mg/kg, p.o.) in the presence or absence of magnolol (625 mg/kg, p.o.). The concentrations of magnolol and piperine in plasma were measured by a validated high performance liquid chromatography (HPLC) method.Results: Compared with control, the groups given magnolol alone, concomitant administration of piperine and magnolol resulted in significant decrease (p < 0.01) in the AUC and Cmax of magnolol. Interestingly, compared with administration of piperine alone (20 mg/kg), co-administration with magnolol did not significantly (p > 0.05) alter the pharmacokinetic parameters of piperine. However, at high dose (40 mg/kg) of piperine, Cmax of piperine significantly decreased from 4.30 ± 1.47 to 2.50 ± 0.78 μg/mL (p < 0.05).Conclusion: Co-administration of magnolol and piperine decreases plasma concentration of either drug in rats, suggesting that concurrent use of magnolol with piperine or piperine-containing diets would require close monitoring for potential interactions.Keywords: Magnolol, Piperine, Pharmacokinetic interaction, Co administratio

Influence of different processing times on the quality of Polygoni Multiflora Radix by metabolomics based on ultra high performance liquid chromatography with quadrupole timeâ ofâ flight mass spectrometry

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/136757/1/jssc5378_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136757/2/jssc5378.pd