改良穴位图谱在中医护理操作中运用效果评价

Objective To find an effective study method to master the nursing procedures of acupoints that will be applied in the clinical nursing work. Methods Based on the Chinese medicine hospital of traditional Chinese medicine nursing guidelines (trial version) published by the bureau of traditional Chinese medicine and given full expression to the advantages of the Traditional Chinese Medicine, acupoints map was improved and was applied in clinical work in August 2011 in our hospital. The nursing operation workload and learning effect in the continuity two years were compared by retrospective investigation combined with questionnaire survey. Results 1, The operation workload increases obviously and the overall growth rate in five work targets is 88.66%, after improving acupoints map of TCM nursing. 2, There are significant differences (P < 0.001) on learning interest, learning degree, memory speed, knowledge of diseas, method of operation and clinical application in our comparison.Conclusion The improved acupoints map can inspire the learning interest of the nursing stuff, help them to master common nursing acupoints of traditional Chinese medicine quickly and apply it to clinical disease. There are good social and economic benefits of this method, so it is worth promoting.目的 寻找一种有效掌握中医护理穴位的学习方法并运用于临床护理工作中。 方法 以中医药局印发《中医医院中医护理工作指南(试行)》文件的内容为指导思想，全面体现中医特色和优势。本院积极开展中医护理操作，于2011年8月设计改良穴位图谱并运用于临床。采用回顾性调查并结合问卷式调查，比较实施前后一年期间中医护理操作工作量及学习效果。结果 （1）2011年8月采用改良穴位图谱后中医护理操作工作量明显增长，五项工作量的总体增长率达88.66%；（2）采用改良穴位图谱前后护士在学习兴趣、易学程度、记忆速度、疾病腧穴知识、操作方法、临床应用等方面比较均有显著性差异（P＜0.001）。 结论 采取改良穴位图谱学习方法能提高护理人员对穴位的学习兴趣，快速掌握中医护理疾病的常用腧穴并应用于临床，赢得了较好的社会效益和经济效益，值得推广

Grain boundary ferromagnetism in vanadium-doped In2_2O3_3 thin films

Room temperature ferromagnetism was observed in In$_2$O$_3 thin films doped with 5 at.temperatures ranging from 300 to 600$\,^{\circ}{\rm C}$. X-ray absorption fine structure measurement indicated that vanadium was substitutionally dissolved in the In$_2$O$_3$ host lattice, thus excluding the existence of secondary phases of vanadium compounds. Magnetic measurements based on SQUID magnetometry and magnetic circular dichroism confirm that the magnetism is at grain boundaries and also in the grains. The overall magnetization originates from the competing effects between grains and grain boundaries.Comment: 12 pages, 7 figures, 1 table, accepted by Europhysics Letter

1-Benzoyl-3,6-diphenyl-1,4-dihydro-1,2,4,5-tetra­zine

In the title compound, C21H16N4O, the central tetra­zine ring adopts an unsymmetrical boat conformation with the two N atoms as the bow and stern. The crystal packing is stabilized by inter­molecular N—H—O hydrogen bonds

Influence of Structure Parameters of Flux Diverters on Performance of Superconducting Energy Storage Coil

This article studies the influence of flux diverters (FDs) on energy storage magnets using high-temperature superconducting (HTS) coils. Based on the simulation calculation of the H equation finite-element model, FDs are placed at both ends of HTS coils, and the position and structure are optimized. The impact of the diverter structural parameters on the energy storage of the HTS energy storage magnet is explored, and an optimized diverter structure is designed. The rectangle is the most basic structure of FDs, so this article first optimizes the structure of the rectangular FDs and then performs various slotting treatments on the optimized FDs. By comparison, it is concluded that the concave FDs have the best energy storage effect. Then, based on the optimization of the concave FDs, a Γ-shaped structure is obtained, further improving the magnet's energy storage effect. The conclusion of the influence factors can be applied to the optimization design of diverter structures and provide a new perspective for improving energy storage.</p

Variational-based data assimilation to simulate sediment concentration in the Lower Yellow River, China

The heavy sediment load of the Yellow River makes it difficult to simulate sediment concentration using classic numerical models. In this paper, on the basis of the classic one-dimensional numerical model of open channel flow, a variational-based data assimilation method is introduced to improve the simulation accuracy of sediment concentration and to estimate parameters in sediment carrying capacity. In this method, a cost function is introduced first to determine the difference between the sediment concentration distributions and available field observations. A one-dimensional suspended sediment transport equation, assumed as a constraint, is integrated into the cost function. An adjoint equation of the data assimilation system is used to solve the minimum problem of the cost function. Field data observed from the Yellow River in 2013 are used to test the proposed method. When running the numerical model with the data assimilation method, errors between the calculations and the observations are analyzed. Results show that (1) the data assimilation system can improve the prediction accuracy of suspended sediment concentration; (2) the variational inverse data assimilation is an effective way to estimate the model parameters, which are poorly known in previous research; and (3) although the available observations are limited to two cross sections located in the central portion of the study reach, the variational-based data assimilation system has a positive effect on the simulated results in the portion of the model domain in which no observations are available

Traditional Chinese medicine combined with hormone therapy to treat premature ovarian failure: a meta-analysis of randomized controlled trials

Background: This meta-analysis aimed to provide critically estimated evidence for the advantages and disadvantages of Chinese herbal medicines used for premature ovarian failure (POF), which could provide suggestions for rational treatments.Materials and Methods: The databases searched included MEDLINE, EMBASE, CNKI, VIP, China Dissertation Database, China Important Conference Papers Database, and online clinical trial registry websites. Published and unpublished randomized controlled trials of traditional Chinese medicine (TCM) combined with hormone therapy (HT) and HT alone for POF were assessed up to December 30, 2015. Two authors extracted data and assessed trial quality independently using Cochrane systematic review methods. Meta-analysis was used to quantitatively describe serum hormone levels and Kupperman scores associated with perimenopause symptoms.Results: Seventeen randomized controlled trials involving 1352 participants were selected. Compared with HT alone, although no significant effects were observed in the levels of luteinizing hormone, therapy with TCM combined with HT compared to HT alone effectively altered serum hormone levels of follicle stimulating hormone (P&lt;0.01) and estradiol (P &lt; 0.01), and improved Kupperman index scores (P&lt; 0.01).Conclusions: The reported favorable effects of TCM combined with HT for treating POF patients are better than HT alone.However,the beneficial effects derived from this combination therapy cannot be viewed conclusive.In order to better support the clinical use, more rigorously designed trials are required to provide.Keywords: Traditional Chinese medicine, Hormone therapy, Premature ovarian failure, Meta-analysi

Efficacy of intravitreal ranibizumab injection combined with macular grid photocoagulation for diabetic macular edema

AIM:To evaluate the clinical efficacy of intravitreal injection of ranibizumab combined with macular grid photocoagulation for diabetic macular edema(DME).<p>METHODS:Totally 60 eyes(60 patients)with DME were randomly divided into 2 groups: 30 eyes of simple injection group underwent intravitreal injection of ranibizumab, and 30 eyes of combined treatment group underwent intravitreal injection of ranibizumab and macular grid photocoagulation 1wk later. The best corrected visual acuity(BCVA), central macular thickness(CMT)measured by optical coherence tomography(OCT)and postoperative complications were observed.<p>RESULTS:In simple injection group, the BCVA after operation were separately 0.390±0.075(4wk), 0.367±0.088(8wk)and 0.319±0.064(12wk),the CMT after operation were separately 221.63±112.34μm(4wk), 337.73±99.56μm(8wk)and 432.92±100.46μm(12wk), which were much better than pre-operation. But during follow-up, the BCVA presented down trend and the CMT was on the rise slowly. In combined treatment group, the BCVA after operation were separately 0.385±0.036(4wk), 0.382±0.079(8wk)and 0.377±0.097(12wk),the CMT after operation were separately 249.77±106.55μm(4wk), 270.40±92.88μm(8wk)and 275.84±97.34μm(12wk), which were satisfactory and steady during follow-up, better than simple injection group(<i>P</i><0.05).<p>CONCLUSION:Intravitreal injection of ranibizumab can effectively improve visual acuity and decrease central foveal thickness for patients with DME, combining with macular grid photocoagulation can ensure therapeutic effects steady and permanent

2-Ferrocenyl-3-meth­oxy-6-methyl­pyridine

In the title compound, [Fe(C5H5)(C12H12NO)], the dihedral angle between the pyridyl and substituted cyclo­penta­dienyl rings is 23.58 (3)°. The crystal structure is characterized by weak inter­molecular C—H⋯N hydrogen-bonding contacts, leading to the formation of chains running parallel to the n-glide planes. A weak inter­molecular C—H⋯π contact is also present

Molecular dynamics simulation of helium ion implantation into silicon and its migration

In this paper, a model of helium ion implanted monocrystalline Si was constructed by using molecular dynamics (MD) simulation method to study the interaction mechanism of helium ion with monocrystalline Si and helium ion migration. In order to study the damage effect of helium ion implantation on monocrystalline Si, identify diamond structure (IDS), radial distribution function, temperature analysis were calculated and analyzed. The effects of ion doses, beam currents and energies on the damage were studied. Helium ion implanted Si with ion doses of 1 x 10(14)/cm(2) was subsequently heated to 300 K. MD simulation results indicated that IDS damage induced by ion implantation was positively correlated with ion doses as the ion implantation increased to 1 x 10(14)/cm(2). The mean-square displacement of helium atoms was calculated during the temperature rising to 300 K. It was found that the high permeability of helium atoms in Si and the acceleration of atomic thermal motion owing to elevated temperature as well as the existence of larger stress would be helpful to the migration of implant helium atoms.Peer reviewe

Spatio-temporal expression of a novel neuron-derived neurotrophic factor (NDNF) in mouse brains during development

<p>Abstract</p> <p>Background</p> <p>Neuron-derived neurotrophic factor (NDNF) is evolutionarily well conserved, being present in invertebrate animals such as the nematode, <it>Caenorhabditis elegans</it>, as well as in the fruit fly, <it>Drosophila melanogaster</it>. Multiple cysteines are conserved between species and secondary structure prediction shows that NDNF is mainly composed of beta-strands. In this study, we aimed to investigate the function of NDNF.</p> <p>Results</p> <p>NDNF is a glycosylated, disulfide-bonded secretory protein that contains a fibronectin type III domain. NDNF promoted migration and growth and elicited neurite outgrowth of mouse hippocampal neurons in culture. NDNF also protected cultured hippocamal neurons against excitotoxicity and amyloid beta-peptide toxicity. Western blotting showed that NDNF was exclusively expressed in the brain and spinal cord. Immunostaining indicated that NDNF was expressed by neurons and not by astrocytes. Cajal-Retzius cells, cortex neurons, hippocampus neurons, olfactory mitral cells, cerebellar purkinje cells, cerebellar granular cells and spinal neurons were found to be NDNF-positive. NDNF expression was observed in the neurons during development.</p> <p>Conclusions</p> <p>The results of this study indicated that NDNF is a novel neurotrophic factor derived from neurons that may be useful in the treatment of neuronal degeneration diseases and nerve injuries.</p