6 research outputs found
Improving Ambipolar Semiconducting Properties of Thiazole-Flanked Diketopyrrolopyrrole-Based Terpolymers by Incorporating Urea Groups in the Side-Chains
Two new ambipolar thiazole-flanked
diketopyrrolopyrrole-based polymers
pDPPTz2T-1 and pDPPTz2T-2 with urea-containing linear side-chains
were prepared. The formation of hydrogen bonding enhanced the ambipolar
semiconducting properties, including mobilities and on/off ratios.
The average mobilities (hole and electron) of pDPPTz2T-2 were 25 and
3 times higher than those of pDPPTz2T without urea groups, whereas
the average on/off ratios (<i>I</i><sub>on</sub>/<i>I</i><sub>off</sub>) for hole and electron were 100 and 4 times
higher than those obtained for pDPPTz2T. Thin-film microstructure
studies reveal that incorporating urea groups into polymer side-chains
can enhance interchain packings, including the alkyl chain lamellar
and π–π stackings. Our results clearly show how
incorporating urea groups in side-chains significantly influence semiconducting
properties, which could be extended to other conjugated systems toward
ambipolar and even n-type FETs
Effects of Dietary Protein from Different Sources on Biotransformation, Antioxidation, and Inflammation in the Rat Liver
In
this work, the effects of different sources of meat protein
on liver metabolic enzymes were investigated. Rats were fed for 90
days with semisynthetic diets in which casein was fully replaced by
isolated soybean, fish, chicken, pork, or beef proteins. Then, liver
proteomics was performed using iTRAQ and LC–ESI–MS/MS.
The results indicated that intake of meat protein diets significantly
reduced the protein levels of CYP450s, GSTs, UGTs, and SULTs compared
to those of the casein and soybean protein diet groups. The total
antioxidant capacity and lipid peroxidation values did not differ
between four meat protein diet groups and the casein diet group. However,
GSH activity in the fish, chicken, and beef protein groups was significantly
higher than those of the casein and soybean protein groups. The beef
protein diet significantly upregulated the expression of immune-related
proteins. The Keap1-Nrf2-ARE signaling pathway was suggested to involve
the diet-mediated regulation of biotransformation, inflammation, and
redox status