207 research outputs found

    Trilepton Signals in the Inert Doublet Model

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    In this work, we investigate the prospects for detecting the Inert Doublet Model via the trilepton channel at the LHC. We present a set of representative benchmark scenarios in which all applicable constraints are satisfied, and show that in some of these scenarios, it is possible to obtain a signal at the 5 sigma significance level or better with integrated luminosity of 300 fb^{-1}.Comment: 15 pages, ReVTeX, 3 figures, 5 tables

    A stableness of resistance model for nonresponse adjustment with callback data

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    Nonresponse arises frequently in surveys and follow-ups are routinely made to increase the response rate. In order to monitor the follow-up process, callback data have been used in social sciences and survey studies for decades. In modern surveys, the availability of callback data is increasing because the response rate is decreasing and follow-ups are essential to collect maximum information. Although callback data are helpful to reduce the bias in surveys, such data have not been widely used in statistical analysis until recently. We propose a stableness of resistance assumption for nonresponse adjustment with callback data. We establish the identification and the semiparametric efficiency theory under this assumption, and propose a suite of semiparametric estimation methods including a doubly robust one, which generalize existing parametric approaches for callback data analysis. We apply the approach to a Consumer Expenditure Survey dataset. The results suggest an association between nonresponse and high housing expenditures

    Effective Multi-Agent Deep Reinforcement Learning Control with Relative Entropy Regularization

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    In this paper, a novel Multi-agent Reinforcement Learning (MARL) approach, Multi-Agent Continuous Dynamic Policy Gradient (MACDPP) was proposed to tackle the issues of limited capability and sample efficiency in various scenarios controlled by multiple agents. It alleviates the inconsistency of multiple agents' policy updates by introducing the relative entropy regularization to the Centralized Training with Decentralized Execution (CTDE) framework with the Actor-Critic (AC) structure. Evaluated by multi-agent cooperation and competition tasks and traditional control tasks including OpenAI benchmarks and robot arm manipulation, MACDPP demonstrates significant superiority in learning capability and sample efficiency compared with both related multi-agent and widely implemented signal-agent baselines and therefore expands the potential of MARL in effectively learning challenging control scenarios

    A review on the usability,flexibility, affinity, and affordability of virtual technology for rehabilitation training of upper limb amputees

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    (1) Background: Prosthetic rehabilitation is essential for upper limb amputees to regain their ability to work. However, the abandonment rate of prosthetics is higher than 50% due to the high cost of rehabilitation. Virtual technology shows potential for improving the availability and cost-effectiveness of prosthetic rehabilitation. This article systematically reviews the application of virtual technology for the prosthetic rehabilitation of upper limb amputees.(2) Methods: We followed PRISMA review guidance, STROBE, and CASP to evaluate the included articles. Finally, 17 articles were screened from 22,609 articles.(3) Results: This study reviews the possible benefits of using virtual technology from four aspects: usability, flexibility, psychological affinity, and long-term affordability. Three significant challenges are also discussed: realism, closed-loop control, and multi-modality integration.(4) Conclusions: Virtual technology allows for flexible and configurable control rehabilitation, both during hospital admissions and after discharge, at a relatively low cost. The technology shows promise in addressing the critical barrier of current prosthetic training issues, potentially improving the practical availability of prosthesis techniques for upper limb amputees

    Benchmarking nearest neighbor retrieval of zebra finch vocalizations across development

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    Vocalizations are highly specialized motor gestures that regulate social interactions. The reliable detection of vocalizations from raw streams of microphone data remains an open problem even in research on widely studied animals such as the zebra finch. A promising method for finding vocal samples from potentially few labelled examples (templates) is nearest neighbor retrieval, but this method has never been extensively tested on vocal segmentation tasks. We retrieve zebra finch vocalizations as neighbors of each other in the sound spectrogram space. Based on merely 50 templates, we find excellent retrieval performance in adults (F1 score of 0.93±0.07) but not in juveniles (F1 score of 0.64±0.18), presumably due to the larger vocal variability of the latter. The performance in juveniles improves when retrieval is based on fixed-size template slices (F1 score of 0.72±0.10) instead of entire templates. Among the several distance metrics we tested such as the cosine and the Euclidean distance, we find that the Spearman distance largely outperforms all others. We release our expert-curated dataset of more than 50’000 zebra finch vocal segments, which will enable training of data-hungry machine-learning approaches

    Remote sensing and social sensing data reveal scale-dependent and system-specific strengths of urban heat island determinants

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    Urban natural surfaces and non-surface human activities are key factors determining the urban heat island (UHI), but their relative importance remains highly controversial and may vary at different spatial scales and focal urban systems. However, systematic studies on the scale-dependency system-specificity remain largely lacking. Here, we selected 32 major Chinese cities as cases and used Landsat 8 images to retrieve land surface temperature (LST) and quantify natural surface variables using point of interest (POI) data as a measure of the human activity variable and using multiple regression and relative weight analysis to study the contribution and relative importance of these factors to LST at a range of grain sizes (0.25–5 km) and spatial extents (20–60 km). We revealed that the contributions and relative importance of natural surfaces and human activities are largely scale-dependent and system-specific. Natural surfaces, especially vegetation cover, are often the most important UHI determinants for a majority of scales, but the importance of non-surface human activities is increasingly pronounced at a coarser spatial scale with respect to both grain and spatial extent. The scaling relations of the UHI determinants and their relative importance were mostly linear-like at the city-collective level, but highly diverse across individual cities, so reducing non-surface heat emissions could be the most effective measure in particular cases, especially at relatively large spatial scales. This study advances the understanding of UHI formation mechanisms and highlights the complexity of the scale issue underpinning the UHI effect

    A Novel Iron Transporter SPD_1590 in Streptococcus pneumoniae Contributing to Bacterial Virulence Properties

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    Streptococcus pneumoniae, a Gram-positive human pathogen, has evolved three main transporters for iron acquisition from the host: PiaABC, PiuABC, and PitABC. Our previous study had shown that the mRNA and protein levels of SPD_1590 are significantly upregulated in the ΔpiuA/ΔpiaA/ΔpitA triple mutant, suggesting that SPD_1590 might be a novel iron transporter in S. pneumoniae. In the present study, using spd1590-knockout, -complemented, and -overexpressing strains and the purified SPD_1590 protein, we show that SPD_1590 can bind hemin, probably supplementing the function of PiuABC, to provide the iron necessary for the bacterium. Furthermore, the results of iTRAQ quantitative proteomics and cell-infection studies demonstrate that, similarly to other metal-ion uptake proteins, SPD_1590 is important for bacterial virulence properties. Overall, these results provide a better understanding of the biology of this clinically important bacterium
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