10 research outputs found
A fleet arithmetic on overlay capacity of multi-aircraft cooperative detect base on transformed chameleon
In allusion to the particularity of Multi-Fighter Cooperative Detection, this paper analyzes the influence of different formation modes of the aircraft.. The framework of basic formation modes is established, moreover, the solutions of these models are also introduced. There is some disadvantage of gridding-method on real-time performance. A transformed chameleon method is used to divide up the big formation and cluster it into the basic ones. The rules-less formationsâ detect an overlay area and divided into basic ones, can be figured out on the ground of dividing results. In this way, we can reduce the fighter formations to calculate the overlay capacity fleetly. The simulation results indicate that the method meet the real-time needs with error permissibility
Integrated analysis identified novel miRNAs and mRNA in endometriosis
Objectives: Endometriosis is a common gynecological disease that seriously affects womenâs health and quality of life. However, the pathogenesis of endometriosis remains uncertain. This study aims to find the key microRNAs (miRNAs) and mRNAs and further to elucidate the pathogenesis of endometriosis.
Material and methods: Differentially expressed mRNAs (DEmRNAs) and the differentially expressed miRNAs (DEmiRNAs) were obtained by Gene Expression Omnibus (GEO) datasets integration analysis. Functional enrichment analysis of DEmRNAs and DEmRNAs targeted by DEmiRNAs was enforced using GeneCodis3. The DEmiRNA-DEmRNA interaction network was built using Cytoscape. The expression of candidate DEmRNA and DEmiRNA was verified using quantitative real time-polymerase chain reaction (QRT-PCR) and online datasets followed by diagnostic and immune cell infiltration analysis.
Results: A total of 835 (327 down-regulated and 508 up-regulated) DEmRNAs and 39 (24 down-regulated and 15 up-regulated) DEmiRNAs were identified between ectopic endometria (EC) group and eutopic endometria (EU) group. DEmRNAs targeted by DEmiRNAs were markedly enriched in cell adhesion molecules, pathways in cancer, leukocyte transendothelial migration, cytokine-cytokine receptor interaction and MAPK signaling pathway. The DEmiRNA-DEmRNA interaction network of up-regulated miRNAs was consisted of 15 miRNAs and 188 corresponding mRNAs. For down-regulated miRNAs, the DEmiRNA-DEmRNA interaction network was consisted of 24 miRNAs and 305 corresponding mRNAs. QRT-PCR validation results of IRF6, PTGER3, NTRK2, hsa-miR-449a and hsa-miR-873-5p were in line with the GEO analysis result. RF6, PTGER3 and NTRK2 had a potential diagnostic value for endometriosis. In addition, the infiltration of macrophages M2 and NK cells activated was the most significantly increased and reduced in ectopic endometrial, respectively.
Conclusions: These identified DEmRNAs and DEmiRNAs may be may be associated with the pathogenesis of endometriosis. The integrated analysis of miRNA and mRNA expression profiles may provide a new perspective for understanding the mechanisms of endometriosis and developing new treatments
One–Step Synthesis of Three–Dimensional Na3V2(PO4)3/Carbon Frameworks as Promising Sodium–Ion Battery Cathode
Sodium–ion batteries (SIBs) are essential for large–scale energy storage attributed to the high abundance of sodium. Polyanion Na3V2(PO4)3 (NVP) is a dominant cathode candidate for SIBs because of its high-voltage and sodium superionic conductor (NASICON) framework. However, the electrochemical performance of NVP is hindered by the inherently poor electronic conductivity, especially for extreme fast charging and long-duration cycling. Herein, we develop a facile one-step in-situ polycondensation method to synthesize the three-dimensional (3D) Na3V2(PO4)3/holey-carbon frameworks (NVP@C) by using melamine as carbon source. In this architecture, NVP crystals intergrown with the 3D holey-carbon frameworks provide rapid transport pathways for ion/electron transmission to increase the ultrahigh rate ability and cycle capability. Consequently, the NVP@C cathode possesses a high reversible capacity of 113.9 mAh g−1 at 100 mA g−1 and delivers an outstanding high–rate capability of 75.3 mAh g−1 at 6000 mA g−1. Moreover, it shows that the NVP@C cathode is able to display a volumetric energy density of 54 Wh L−1 at 6000 mA g−1 (31 Wh L−1 for NVP bulk), as well as excellent cycling performance of 65.4 mAh g−1 after 1000 cycles at 2000 mA g−1. Furthermore, the NVP@C exhibits remarkable reversible capabilities of 81.9 mAh g−1 at a current density of 100 mA g−1 and 60.2 mAh g−1 at 1000 mA g−1 even at a low temperature of −15 °C. The structure of porous carbon frameworks combined with single crystal materials by in-situ polycondensation offers general guidelines for the design of sodium, lithium and potassium energy storage materials
OneâStep Synthesis of ThreeâDimensional Na<sub>3</sub>V<sub>2</sub>(PO<sub>4</sub>)<sub>3</sub>/Carbon Frameworks as Promising SodiumâIon Battery Cathode
Sodiumâion batteries (SIBs) are essential for largeâscale energy storage attributed to the high abundance of sodium. Polyanion Na3V2(PO4)3 (NVP) is a dominant cathode candidate for SIBs because of its high-voltage and sodium superionic conductor (NASICON) framework. However, the electrochemical performance of NVP is hindered by the inherently poor electronic conductivity, especially for extreme fast charging and long-duration cycling. Herein, we develop a facile one-step in-situ polycondensation method to synthesize the three-dimensional (3D) Na3V2(PO4)3/holey-carbon frameworks (NVP@C) by using melamine as carbon source. In this architecture, NVP crystals intergrown with the 3D holey-carbon frameworks provide rapid transport pathways for ion/electron transmission to increase the ultrahigh rate ability and cycle capability. Consequently, the NVP@C cathode possesses a high reversible capacity of 113.9 mAh gâ1 at 100 mA gâ1 and delivers an outstanding highârate capability of 75.3 mAh gâ1 at 6000 mA gâ1. Moreover, it shows that the NVP@C cathode is able to display a volumetric energy density of 54 Wh Lâ1 at 6000 mA gâ1 (31 Wh Lâ1 for NVP bulk), as well as excellent cycling performance of 65.4 mAh gâ1 after 1000 cycles at 2000 mA gâ1. Furthermore, the NVP@C exhibits remarkable reversible capabilities of 81.9 mAh gâ1 at a current density of 100 mA gâ1 and 60.2 mAh gâ1 at 1000 mA gâ1 even at a low temperature of â15 °C. The structure of porous carbon frameworks combined with single crystal materials by in-situ polycondensation offers general guidelines for the design of sodium, lithium and potassium energy storage materials
Investigation on a Sensitive Chemiluminescence System Based on Ni(IV) Complex to Determine Two ÎČ2-Agonist Drugs in Urine and Swine Feed and Their Mechanism
Veterinary drug residues, particularly traces of β2-agonists, can cause various kinds of harmful impact to the environment and public health. Here, a sensitive chemiluminescence (CL) method incorporated with a flow injection analysis is developed for the determination of two β2-agonists [i.e., salbutamol (SAL) and terbutaline (TEB)]. The system is based on the CL reaction of Ni(IV) complex with luminol in alkaline solutions, whereas SAL and TEB can significantly enhance CL intensities. Under optimum conditions, CL intensities are proportional to the SAL and TEB concentration in the range of 1.0 × 10−9 M to 5.0 × 10−7 M and 1.0 × 10−9 M to 1.0 × 10−7 M, respectively. The limits of detection (3σ) are 1.0 × 10−11 M for TEB, and 1.3 × 10−11 for SAL respectively. Relative standard deviations (n = 11) are less than 2% for 5.0 × 10−8 M SAL and TEB. Possible reaction mechanisms for the CL system are suggested based on the CL system spectra, Ni(IV) complex oxidation characteristics, and electron spin resonance (ESR) techniques. The proposed method has been applied to the analysis of urine and swine feed samples with satisfactory results