155 research outputs found

    Global Earth’s gravity field solution with GRACE orbit and range measurements using modified short arc approach

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    Traditionally, the Earth’s gravity field model is computed from GRACE orbit and range rate measurements, e.g., in a short arc approach where both the position and the velocity vectors are integrated from a force model. In this contribution, we use the GRACE orbit and range measurements to recover the Earth’s gravity field model, thus we only need to integrate the position vectors. We use the range differences between two adjacent epochs to eliminate the range ambiguities. Using GRACE Level-1B RL02 data released by Jet Propulsion laboratory, the gravity field model TJGRACE02O complete to degree and order 90 is developed from 7 years of reduced dynamic orbits covering the period 2004–2010, and the gravity field model TJGRACE02K complete to degree and order 120 is computed from 1 month of kinematic orbits and K-band range data of January. Comparing the degree geoid errors of our new models with recent gravity field models such as the CHAMP-only models EIGEN-CHAMP05S, AIUB-CHAMP03S, ULUX-CHAMP2013S and the GRACE-only models GGM05S, Tongji-GRACE01 as well as a monthly model from the ITG-GRACE2010 time series, and validating these models with GPS-leveling data sets in the USA, we can conclude that the TJGRACE02O model is more accurate than all the CHAMP-only models and TJGRACE02K is comparable in quality to the corresponding GRACE monthly model from ITG-GRACE2010.Department of Land Surveying and Geo-Informatic

    An optimized short-arc approach: methodology and application to develop refined time series of Tongji-Grace2018 GRACE monthly solutions

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    Abstract Considering the unstable inversion of ill-conditioned intermediate matrix required in each integral arc in the short-arc approach presented in Chen et al. (2015), an optimized short-arc method via stabilizing the inversion is proposed. To account for frequency-dependent noise in observations, a noise whitening technique is implemented in the optimized short-arc approach. Our study shows the optimized short-arc method is able to stabilize the inversion and eventually prolong the arc length to 6 hours. In addition, the noise whitening method is able to mitigate the impacts of low-frequency noise in observations. Using the optimized short-arc approach, a refined time series of GRACE monthly models called Tongji-Grace2018 has been developed. The analyses allow us to derive the following conclusions: (a) during the analyses over the river basins (i.e. Amazon, Mississippi, Irrawaddy and Taz) and Greenland, the correlation coefficients of mass changes between Tongji-Grace2018 and others (i.e. CSR RL06, GFZ RL06 and JPL RL06 Mascon) are all over 92 and the corresponding amplitudes are comparable; (b) the signals of Tongji-Grace2018 agree well with those of CSR RL06, GFZ RL06, ITSG-Grace2018 and JPL RL06 Mascon, while Tongji-Grace2018 and ITSG-Grace2018 are less noisy than CSR RL06 and GFZ RL06; (c) clearer global mass change trend and less striping noise over oceans can be observed in Tongji-Grace2018 even only using decorrelation filtering; and (d) for the tests over Sahara, over 36 and 19 of noise reductions are achieved by Tongji-Grace2018 relative to CSR RL06 in the cases of using decorrelation filtering and combined filtering, respectively

    Experimental study on thiosulfate leaching of gold from a high copper gold concentrate

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    The conventional cyanide leaching process is used to extract gold from a high copper gold concentrate. Because the copper associated minerals consume sodium cyanide in large quantities, the cost of the reagents is high and the economic benefit is not ideal. At the same time, a large number of cyanide tail slag are produced, which brings a series of environmental problems. In order to solve the environmental problems caused by excessive sodium cyanide consumption and cyanogen slag, the feasibility of leaching gold by thiosulfate in copper ammonia system was studied. The gold leaching rate of thiosulfate was increased to more than 90% by using the direct thiosulfate leaching process and pretreatment thiosulfate leaching process, which was close to the gold leaching index of sodium cyanide at the production site

    Study on recovery of copper and zinc from cyanide lean solution in a smelting company

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    In the process of cyanidation of gold concentrate from a smelting company, the content of copper and zinc in the liquid gradually increased. In production, acidizing process is used to treat the lean solution from high copper concentrate, and mixed products containing copper, zinc and other metals are produced. In this paper, the pH value of zinc precipitation is 6.0 and the pH value of copper precipitation is 3.0 through theoretical calculation and experiment. The separation of copper and zinc in the lean solution is realized successfully. The zinc product with grade of 42.97% and the copper product with grade of 58.33% are produced

    Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study

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    <p>Abstract</p> <p>Background</p> <p>Lung cancer is one of the most malignant tumors, representing a significant threat to human health. Lung cancer patients often exhibit tumor cell invasion and metastasis before diagnosis which often render current treatments ineffective. Here, we investigated the effect of staurosporine, a potent protein kinase C (PKC) inhibitor on the mobility and invasiveness of human lung adenocarcinoma A549 cells.</p> <p>Methods</p> <p>All experiments were conducted using human lung adenocarcinoma A549 cells that were either untreated or treated with 1 nmol/L, 10 nmol/L, or 100 nmol/L staurosporine. Electron microscopy analyses were performed to study ultrastructural differences between untreated A549 cells and A549 cells treated with staurosporine. The effect of staurosporine on the mobility and invasiveness of A549 was tested using Transwell chambers. Western blot analyses were performed to study the effect of staurosporine on the levels of PKC-α, integrin β1, E-cadherin, and LnR. Changes in MMP-9 and uPA levels were identified by fluorescence microscopy.</p> <p>Results</p> <p>We demonstrated that treatment of A549 cells with staurosporine caused alterations in the cell shape and morphology. Untreated cells were primarily short spindle- and triangle-shaped in contrast to staurosporine treated cells which were retracted and round-shaped. The latter showed signs of apoptosis, including vacuole fragmentation, chromatin degeneration, and a decrease in the number of microvilli at the surface of the cells. The A549 cell adhesion, mobility, and invasiveness significantly decreased with higher staurosporine concentrations. E-cadherin, integrin β1, and LnR levels changed by a factor of 1.5, 0.74, and 0.73, respectively compared to untreated cells. In addition, the levels of MMP-9 and uPA decreased in cells treated with staurosporine.</p> <p>Conclusion</p> <p>In summary, this study demonstrates that staurosporine inhibits cell adhesion, mobility, and invasion of A549 cells. The staurosporine-mediated inhibition of PKC-α, induction of E-Cad expression, and decreased integrin β1, LnR, MMP-9, and uPA levels could all possibly contribute to this biological process. These results represent a significant step forward in the ongoing effort to understand the development of lung carcinoma and to design novel strategies to inhibit metastasis of the tumor by targeting the cell-adhesion, mobility and invasion of tumor cells.</p

    The gap in injury mortality rates between urban and rural residents of Hubei province, China

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    <p>Abstract</p> <p>Background</p> <p>Injury is a growing public health concern in China. Injury death rates are often higher in rural areas than in urban areas in general. The objective of this study is to compare the injury mortality rates in urban and rural residents in Hubei Province in central China by age, sex and mechanism of injury.</p> <p>Methods</p> <p>Using data from the Disease Surveillance Points (DSP) system maintained by the Hubei Province Centers for Disease Control and Prevention (CDC) from 2006 to 2008, injury deaths were classified according to the International Classification of Disease-10<sup>th </sup>Revision (ICD-10). Crude and age-adjusted annual mortality rates were calculated for rural and urban residents of Hubei Province.</p> <p>Results</p> <p>The crude and age-adjusted injury death rates were significantly higher for rural residents than for urban residents (crude rate ratio 1.9, 95% confidence interval 1.8-2.0; adjusted rate ratio 2.4, 95% confidence interval 2.3-2.4). The age-adjusted injury death rate for males was 81.6/100,000 in rural areas compared with 37.0/100 000 in urban areas; for females, the respective rates were 57.9/100,000 and 22.4/100 000. Death rates for suicide (32.4 per 100 000 vs 3.9 per 100 000), traffic-related injuries (15.8 per 100 000 vs 9.5 per 100 000), drowning (6.9 per 100 000 vs 2.3 per 100 000) and crushing injuries (2.0 per 100 000 vs 0.7 per 100 000) were significantly higher in rural areas. Overall injury death rates were much higher in persons over 65 years, with significantly higher rates in rural residents compared with urban residents for suicide (279.8 per 100 000 vs 10.7 per 100 000), traffic-related injuries, and drownings in this age group. Death rates for falls, poisoning, and suffocation were similar in the two geographic groups.</p> <p>Conclusions</p> <p>Rates of suicide, traffic-related injury deaths and drownings are demonstrably higher in rural compared with urban locations and should be targeted for injury prevention activity. There is a need for injury prevention policies targeted at elderly residents, especially with regard to suicide prevention in rural areas in Central China.</p

    Variational principles for topological pressures on subsets

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    In this paper, we investigate the relations between various types of topological pressures and different versions of measure-theoretical pressures. We extend Feng- Huang's variational principle for packing entropy to packing pressure and obtain two new variational principles for Pesin-Pitskel and packing pressures respectively. We show that various types of Katok pressures for an ergodic measure with respect to a potential function are equal to the sum of measure-theoretic entropy of this measure and the integral of the potential function. Moreover, we obtain Billingsley type theorem for packing pressure, which indicates that packing pressure can be determined by measure-theoretic upper local pressure of measures, and a variational principle for packing pressure of the set of generic points for any invariant ergodic Borel probability measure.Comment: 25 pages. arXiv admin note: text overlap with arXiv:1012.1103, arXiv:1111.7121 by other author
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