The Analysis of the Internal Forces in Strengthened Old Concrete Bridge Subject to Vehicular Load by Transforming Simply Supported into Continuous System

In the past half century, large numbers of simply supported bridges were constructed in China; however, with the passing of years and the increase in the volume of transport, many of the bridges are out of normal service level and even gradually lose their bearing capacity due to overload or environmental influence. Therefore, some strengthening works have to be carried out in order for these old bridges to work well. Among the common strengthening methods, an efficient way to transform a simply supported into a continuous system is widely used in simply supported bridges with small or medium span. After the transformation of the system, the internal forces in the bridge are redistributed. This paper investigated, using the FEM software ANSYS, both the endogen forces of an old T-type bridge transformed from a simply supported to a continuous system under vehicular load. The result of the analysis indicates that the flexural moments in mid-span of all lateral T beams are significantly decreased and negative moments at supports are formed, while the shear forces in controlling sections are increased that are required to be reinforced based on the computation. In addition, after transformation, both longitudinal and lateral stiffnesses of T beams are improved that provides beneficial effects on the deflections of the bridge

Why torus-unstable solar filaments experience failed eruption?

To investigate the factors that control the success and/or failure of solar eruptions, we study the magnetic field and 3-Dimensional (3D) configuration of 16 filament eruptions during 2010 July - 2013 February. All these events, i.e., erupted but failed to be ejected to become a coronal mass ejection (CME), are failed eruptions with the filament maximum height exceeding $100 Mm$. The magnetic field of filament source regions is approximated by a potential field extrapolation method. The filament 3D configuration is reconstructed from three vantage points by the observations of STEREO Ahead/Behind and SDO spacecraft. We calculate the decay index at the apex of these failed filaments and find that in 7 cases, their apex decay indexes exceed the theoretical threshold ($n_{crit} = 1.5$) of the torus instability. We further determine the orientation change or rotation angle of each filament top during the eruption. Finally, the distribution of these events in the parameter space of rotation angle versus decay index is established. Four distinct regimes in the parameter space are empirically identified. We find that, all the torus-unstable cases (decay index $n > 1.5$), have a large rotation angles ranging from $50^\circ - 130^\circ$. The possible mechanisms leading to the rotation and failed eruption are discussed. These results imply that, besides the torus instability, the rotation motion during the eruption may also play a significant role in solar eruptions

Mass-induced sea level change in the northwestern North Pacific and its contribution to total sea level change

Author Posting. © American Geophysical Union, 2013. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 40 (2013): 3975–3980, doi:10.1002/grl.50748.Over the period 2003–2011, the Gravity Recovery and Climate Experiment (GRACE) satellite pair revealed a remarkable variability in mass-induced sea surface height (MSSH) in the northwestern North Pacific. A significant correlation is found between MSSH and observed total sea surface height (SSH), indicative of the importance of barotropic variability in this region. For the period 2003–2011, MSSH rose at a rate of 6.1 ± 0.7 mm/yr, which has a significant contribution to the SSH rise (8.3 ± 0.7 mm/yr). Analysis of the barotropic vorticity equation based on National Centers for Environmental Prediction/National Center for Atmospheric Research reanalysis product, GRACE, and altimetry data suggests that the MSSH signal is primarily caused by negative wind stress curl associated with an anomalous anticyclonic atmospheric circulation. Regression analysis indicates that trends in MSSH and surface wind are related to the Pacific Decadal Oscillation, whose index had a decreasing trend in the last decade.This work was supported by the National Basic Research Program of China (2010CB950303 and 2012CB955603) and the National Natural Science Foundation of China (41176023, 41276108, and 41006006). X.H.C. is also sponsored by “Youth Innovation Promotion Association,” CAS (SQ201204, LTOZZ1202).2014-02-0

Increased incidence of thyroid disease in patients with sarcoidosis: a systematic review and meta-analysis

Background: Sarcoidosis is a multiple systemic granulomatous disease, and its main pathological feature is non-caseous necrotic epithelial granuloma. The pathogenesis is not fully understood. The prevalence of thyroid disease is like ly higher among individuals with sarcoidosis. However, this association still lacks clinica l evidence. Objective: The aim of this study was to estimate the incidence of thyroid disease in patients with sarcoidosis. Methods: A literature search was conducted using PubMed, Web of Science , Embase, and China National Knowledge Infrastructure literature databases. Fixed- or random-effects models were used for analysis according to heterogeneity. The r esults were subjected to meta-analysis with odds ratios (ORs) and corresponding 95% confi dence intervals (CIs). Results: In total, six articles were included in this meta-analysis, wh ich involved 2044 sarcoidosis cases and 5652 controls. The studies found that the incidence of thyroid disease in patients with sarcoidosis was significantly increased compared to the controls (OR 3.28, 95% CI 1.83–5.88). Conclusions: This systematic review is the first to evaluate the incidence o f thyroid disease in sarcoidosis patients, which was increased compared with the controls, suggesting that sarcoidosis patients should be screened for thyroid disease

Extensive Particle Identification with TPC and TOF at the STAR Experiment

Particle identification (PID) capabilities are studied by using the Time Projection Chamber (TPC) and a Time-Of-Flight (TOF) detector together at STAR. The identification capability of charged hadrons is greatly extended compared with that achieved by TPC and TOF separately. Particle spectra from p+p, d+Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV and Au+Au collisions at $\sqrt{s_{_{NN}}}=62.4$ GeV are used to develop the methods. The transverse momentum ($p_T$) ranges of $\pi$, and $p(\bar{p})$ identification are from $\sim0.3$ GeV/$c$ to $\sim10$ GeV/$c$. The high $p_T$ reach is limited by statistics in current data sets. An important conceptual advance was developed to identify electrons by using a combination of dE/dx in TPC and velocity information from the TOF detectors, which is important for future low-mass dilepton program at STAR.Comment: 19 pages, 22 figures, 3 tables, submitted to NIM

Twenty-four-hour ambulatory blood pressure variability and association with ischemic stroke subtypes in the subacute stage

Background and purposeBlood pressure (BP) variability (BPV) increases the risk of cerebral disease in both hemorrhagic and ischemic strokes. However, whether BPV is associated with different types of ischemic stroke remains unclear. In this study, we explored the relationship between BPV and ischemic stroke subtypes.MethodsWe enrolled consecutive patients aged 47–95 years with ischemic stroke in the subacute stage. We categorized them into four groups based on their artery atherosclerosis severity, brain magnetic resonance imaging markers, and disease history: large-artery atherosclerosis, branch atheromatous disease, small-vessel disease, and cardioembolic stroke. Twenty-four-hour ambulatory blood pressure monitoring was performed, and the mean systolic blood pressure/diastolic blood pressure, standard deviation, and coefficient of variation were calculated. A multiple logistic regression model and random forest were used to test the relationship between BP and BPV in the different types of ischemic stroke.ResultsA total of 286 patients, including 150 men (73.0 ± 12.3 years) and 136 women (77.8 ± 9.6 years) were included in the study. Of these, 86 (30.1%) patients had large-artery atherosclerosis, 76 (26.6%) had branch atheromatous disease, 82 (28.7%) had small-vessel disease, and 42 (14.7%) had cardioembolic stroke. There were statistically significant differences in BPV between subtypes of ischemic stroke in 24-h ambulatory blood pressure monitoring. The random forest model showed that BP and BPV were important features associated with ischemic stroke. Multinomial logistic regression analysis demonstrated that systolic blood pressure levels; systolic blood pressure variability at 24 h, daytime and nighttime; and nighttime diastolic blood pressure were independent risk factors for large-artery atherosclerosis after adjustment for confounders. When compared to branch atheromatous disease and small-vessel disease, nighttime diastolic blood pressure and standard deviation of diastolic blood pressure were significantly associated with patients in the cardioembolic stroke group. However, a similar statistical difference was not seen in patients with large-artery atherosclerosis.ConclusionThe results of this study indicate a discrepancy in blood pressure variability among different ischemic stroke subtypes during the subacute stage. Higher systolic blood pressure and systolic blood pressure variability during the 24 h, daytime, and nighttime, and nighttime diastolic blood pressure were independent predictors for large-artery atherosclerosis stroke. Increased nighttime diastolic BPV was an independent risk factor for cardioembolic stroke

High-performance chiral all-optical logic gate based on topological edge states of valley photonic crystal

For all-optical communication and information processing, it is necessary to develop all-optical logic gates based on photonic structures that can directly perform logic operations. All-optical logic gates have been demonstrated based on conventional waveguides and interferometry, as well as photonic crystal structures. Nonetheless, any defects in those structures will introduce high scattering loss, which compromises the fidelity and contrast ratio of the information process. Based on the spin-valley locking effect that can achieve defect-immune unidirectional transmission of topological edge states in valley photonic crystals (VPCs), we propose a high-performance all-optical logic OR gate based on a VPC structure. By tuning the working bandwidth of the two input channels, we prevent interference between the two channels to achieve a stable and high-fidelity output. The transmittance of both channels is higher than 0.8, and a high contrast ratio of 28.8 dB is achieved. Moreover, the chirality of the logic gate originated from the spin-valley locking effect allows using different circularly polarized light as inputs, representing "1" or "0", which is highly desired in quantum computing. The device's footprint is small, allowing high-density on-chip integration. In addition, this design can be experimentally fabricated using current nanofabrication techniques and will have potential applications in optical communication, information processing, and quantum computing.Comment: 10 pages, 6 figure

The Protective Effects of Trypsin Inhibitor on Hepatic Ischemia-Reperfusion Injury and Liver Graft Survival

The aim of this study was to explore the protective effects of ulinastatin (urinary trypsin inhibitor, UTI) on liver ischemia-reperfusion injury (IRI) and graft survival. We employed mouse liver cold IRI and orthotopic liver transplantation (OLTx) models. UTI was added to lactated Ringer’s (LR) solution for liver perfusion and preservation in vitro or combined with UTI injection intraperitoneally to the liver graft recipient. Our results indicated that UTI supplementation protected the liver from cold IRI in a dose-dependent manner and prolonged liver graft survival from extended cold preserved liver donors significantly. The underlying mechanism of UTI on liver IRI may be mediated by inhibition of proinflammatory cytokine release, increasing the expression of the antiapoptotic gene Bcl-2 and decreasing the expression of the proapoptosis genes of Caspase-3 and Bax, and further protects hepatocytes from apoptotic death and improves liver function