25 research outputs found

    Factors influencing patient’s medical choice behavior on Internet Medical: The perspective of trust

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    Based on the source credibility model and trust transfer theory, this study examined the influence of physician’s personal attributes and word-of-mouth on patients’ medical choice in online healthcare communities, and explored trust transfer from online to offline channel as well as the moderating effect of disease risk on the influence of ability trust and honest trust. Using data from Good Doctor Online, the results revealed that ability trust, benevolence trust, honest trust, and transference trust based on word-of-mouth all had a positive impact on the patients’ medical choice despite slight differences between channels in terms of specific proxies and degree of influence. Disease risk moderated the relationship between ability trust and honest trust and patients’ medical choice. Trust transfer from online channel to offline channel had not been verified

    Potable Water Reuse through Advanced Membrane Technology

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    © 2018 American Chemical Society. Recycling water from municipal wastewater offers a reliable and sustainable solution to cities and regions facing shortage of water supply. Places including California and Singapore have developed advanced water reuse programs as an integral part of their water management strategy. Membrane technology, particularly reverse osmosis, has been playing a key role in producing high quality recycled water. This feature paper highlights the current status and future perspectives of advanced membrane processes to meet potable water reuse. Recent advances in membrane materials and process configurations are presented and opportunities and challenges are identified in the context of water reuse

    Multiscale acoustic emission of C/SiC mini-composites and damage identification using pattern recognition

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    In this paper, multiscale acoustic emission (AE) signal analysis was applied to acoustic emission data processing to classify the AE signals produced during the tensile process of C/SiC mini-composites. An established unsupervised clustering algorithm was provided to classify an unknown set of AE data into reasonable classes. In order to correctly match the obtained classes of the AE signals with the damage mode of the sample, three scales of materials were involved. Single fiber tensile test and fiber bundle tensile test were firstly performed to achieve the characteristics of AE signal of fiber fracture. Parameter analysis and waveform analysis were added to extract the different features of each class of signals in the In-situ tensile test of C/SiC mini-composite. The change of strain field on the sample surface analyzed by DIC (Digital Image Correlation) revealed the corresponding relationship between matrix cracking and AE signals. Microscopic examinationwas used to correlate the clusters to the damage mode. By analyzing the evolution process of signal activation for each class against the load, it also provided a reliable basis for the correlation between the obtained classes of the AE signals and the damage mechanism of the material

    In-plane shear experimental method and mechanical behavior of ceramic matrix mini-composites

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    In-plane shear mechanical experiments of ceramic matrix mini-composites (CMMC) were realized in this paper by overcoming the difficulties of material preparation, specimen design, gripping and loading, deformation measurement, etc. The in-plane shear stress-strain responses of different matrix volume fractions were obtained based on the method. The stress-strain response of CMMC was strongly non-linear, and its elastic modulus and strength were positively correlated to the matrix volume fraction. The main factors affecting the digital image correlation (DIC) based micro-region shear deformation measurement are analyzed quantitatively, and the corresponding solutions are discussed. The DIC calculation time model is established, and the accurate estimation of DIC processing time is realized. The shear strain field evolution clearly captured the matrix crack initiation and propagation

    Tweak in Puzzle:Tailoring Membrane Chemistry and Structure toward Targeted Removal of Organic Micropollutants for Water Reuse

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    Membrane-based water reuse through reverse osmosis (RO) and nanofiltration (NF) faces a critical challenge from organic micropollutants (OMPs). Conventional polyamide RO and NF membranes often lack adequate selectivity to achieve sufficient removal of toxic and harmful OMPs in water. Tailoring membrane chemistry and structure to allow highly selective removal of OMPs has risen as an important topic in membrane-based water reuse. However, a critical literature gap remains to be addressed: how to design membranes for more selective removal of OMPs. In this review, we critically analyzed the roles of membrane chemistry and structure on the removal of OMPs and highlighted opportunities and strategies toward more selective removal of OMPs in the context of water reuse. Specifically, we statistically analyzed rejection of OMPs by conventional polyamide membranes to illustrate their drawbacks on OMPs removal, followed by a discussion on the underlying fundamental mechanisms. Corresponding strategies to tailor membrane properties for improving membrane selectivity against OMPs, including surface modification, nanoarchitecture construction, and deployment of alternative membrane materials, were systematically assessed in terms of water permeance, OMPs rejection, and water-OMPs selectivity. In the end, we discussed the potential and challenges of various strategies for scale-up in real applications. </p

    Stable superhydrophobic ceramic-based carbon nanotube composite desalination membranes

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    Membrane distillation (MD) is a promising process for the treatment of highly saline wastewaters. The central component of MD is a stable porous hydrophobic membrane with a large liquid–vapor interface for efficient water vapor transport. A key challenge for current polymeric or hydrophobically modified inorganic membranes is insufficient operating stability, resulting in some issues such as wetting, fouling, flux, and rejection decline. This study presents an overall conceptual design and application strategy for a superhydrophobic ceramic–based carbon nanotube (CNT) desalination membrane having specially designed membrane structures with unprecedented operating stability and MD performance. Superporous and superhydrophobic surface structures with CNT networks are created after quantitative regulation of in situ grown CNT. The fully covered CNT layers (FC–CNT) exhibit significantly improved thermally and superhydrophobically stable properties under an accelerated stability test. Due to the distinctive structure of the superporous surface network, providing a large liquid–vapor superhydrophobic interface and interior finger-like macrovoids, the FC–CNT membrane exhibits a stable high flux with a 99.9% rejection of Na+, outperforming existing inorganic membranes. Under simple and nondestructive electrochemically assisted direct contact MD (e-DCMD), enhanced antifouling performance is observed. The design strategy is broadly applicable to be extended toward fabrication of high performance membranes derived from other ceramic or inorganic substrates and additional applications in wastewater and gas treatment

    Prediction of H3K27M Alteration Status in Brainstem Glioma Using Multi-Shell Diffusion MRI Metrics

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    Background: Multi-shell diffusion characteristics may help characterize brainstem gliomas (BSGs) and predict H3K27M status. // Purpose: To identify the diffusion characteristics of BSG patients and investigate the predictive values of various diffusion metrics for H3K27M status in BSG. // Study Type: Prospective. // Population: Eighty-four BSG patients (median age 10.5 years [IQR 6.8–30.0 years]) were included, of whom 56 were pediatric and 28 were adult patients. // Field Strength/Sequence: 3 T, multi-shell diffusion imaging. // Assessment: Diffusion kurtosis imaging and neurite orientation dispersion and density imaging analyses were performed. Age, gender, and diffusion metrics, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity, radial diffusivity (RD), mean kurtosis (MK), axial kurtosis (AK), radial kurtosis, intracellular volume fraction (ICVF), orientation dispersion index, and isotropic volume fraction (ISOVF), were compared between H3K27M-altered and wildtype BSG patients. // Statistical Tests: Chi-square test, Mann–Whitney U test, multivariate analysis of variance (MANOVA), step-wise multivariable logistic regression. P-values <0.05 were considered significant. // Results: 82.4% pediatric and 57.1% adult patients carried H3K27M alteration. In the whole group, the H3K27M-altered BSGs demonstrated higher FA, AK and lower RD, ISOVF. The combination of age and median ISOVF showed fair performance for H3K27M prediction (AUC = 0.78). In the pediatric group, H3K27M-altered BSGs showed higher FA, AK, MK, ICVF and lower RD, MD, ISOVF. The combinations of median ISOVF, 5th percentile of FA, median MK and median MD showed excellent predictive power (AUC = 0.91). In the adult group, H3K27M-altered BSGs showed higher ICVF and lower RD, MD. The 75th percentile of RD demonstrated fair performance for H3K27M status prediction (AUC = 0.75). // Data Conclusion: Different alteration patterns of diffusion measures were identified between H3K27M-altered and wildtype BSGs, which collectively had fair to excellent predictive value for H3K27M alteration status, especially in pediatric patients. // Evidence Level: 2 // Technical Efficacy: Stage
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