Recent U.S. and China's Trade Issues

International Relations/Trade,

Technology and Special Education: Designing Effective Professional Development for Equitable and Inclusive Classrooms

This dissertation investigates the adaptation of a research-based professional development approach, Innovating Instruction, for special education teachers. This adapted approach uses assistive technology (AT) as a catalyst for helping teachers acquire design skills needed to include more inquiry-based practices. The adapted approach introduces effective teaching practices based on the learning sciences and demonstrates multiple ways to use AT to meet the needs of students. To address the “unexamined link between the use of design practices and the introduction of technology within a learning science framework,” (Meier, 2018, p.142), the Innovating Instruction© professional development framework (2018) at the Center for Technology and School Change provides a three-part approach to implement these changes: design, situate, lead. Two recent National Science Foundation grants have established the model’s positive impact on teachers’ ability to design projects, to shift from disciplinary to transdisciplinary project design, and to shift instructional thinking to include inquiry-based approaches. This dissertation responds to an important challenge in special education: the limited opportunities to prepare special education teachers to provide high-quality instruction to support all students. It uses technology as a catalyst to help special education teachers learn about design practices that engage students in inquiry practices that are culturally relevant and build on student strengths. The intervention introduced teachers to inquiry-driven design practices and used technology that supported new ways of understanding the capacity of special needs students through a six-month professional development program. The research design used was a convergent parallel mixed methods approach to analyze both qualitative and qualitative data to capture how special education teachers used AT to design inquiry-based learning. The analysis revealed a statistically significant shift over the period of the professional development, implementation, and reflection phases in terms of teachers’ ability to design inquiry-based projects that integrated AT. Also, the findings showed the importance of “situating” teachers’ needs, encouraging collaborative learning with colleagues, and developing a shared knowledge base of inquiry-based teaching strategies in special education classrooms. Findings from teacher questionnaires and interviews showed emerging leadership activities: teachers took more initiative to design projects and collaborate with other teachers in the school community

Quantification of Feed Crop Supply and Demand in Idaho, 2003 – 2021

The expansion of the dairy industry in Idaho over the past two decades has impacted the supply and demand for feed crops in the State and Western U.S. This article presents a method for quantifying state level feed crop supply and demand on an annual basis. Results show that demand has exceeded supply for corn grain for the entire study period of 2003 to 2021, while supply and demand are largely at parity for alfalfa hay, corn silage, and barley. The extent to which feed demand is met by local or external supply has implications for risk management decisions for feed crop stakeholders in properly accounting for local production and external market risks

Thermopower and Nernst measurements in a half-filled lowest Landau level

Motivated by recent proposal by Potter et al. [Phys. Rev. X 6, 031026 (2016)] concerning possible thermoelectric signatures of Dirac composite fermions, we perform a systematic experimental study of thermoelectric transport of an ultrahigh-mobility GaAs/AlxGa1-xAs two dimensional electron system at filling factor v = 1/2. We demonstrate that the thermopower Sxx and Nernst Sxy are symmetric and anti-symmetric with respect to B = 0 T, respectively. The measured properties of thermopower Sxx at v = 1/2 are consistent with previous experimental results. The Nernst signals Sxy of v = 1/2, which have not been reported previously, are non-zero and show a power law relation with temperature in the phonon-drag dominant region. In the electron-diffusion dominant region, the Nernst signals Sxy of v = 1/2 are found to be significantly smaller than the linear temperature dependent values predicted by Potter et al., and decreasing with temperature faster than linear dependence.Comment: 23 pages, 5 figure

De-Pinning Transition of Bubble Phases in a High Landau Level

While in the lowest Landau level the electron-electron interaction leads to the formation of the Wigner crystal, in higher Landau levels a solid phase with multiple electrons in a lattice site of crystal was predicted, which was called the bubble phase. Reentrant integer quantum Hall states are believed to be the insulating bubble phase pinned by disorder. We carry out nonlinear transport measurements on the reentrant states and study the de-pinning of the bubble phase, which is complementary to previous microwave measurements and provides unique information. In this study, conductivity is directly measured with Corbino geometry. Based on the threshold electric field of de-pinning, a phase diagram of the reentrant state is mapped. We discuss an interaction-driven topological phase transition between the integer quantum Hall state and the reentrant integer quantum Hall state.Comment: 11 pages, 3 figure

Inhibition of autophagy promotes sonodynamic therapy-induced apoptosis of pancreatic cancer cells

Introduction. Sonodynamic therapy (SDT), a promising non-invasive therapeutic modality, has attracted increasing attention in the treatment of pancreatic cancer (PC). At present, the role of autophagy in SDT of PC remains unclear. This study aims to explore the role of autophagy in SDT of PC and its effect on apoptosis of PC cells. Material and methods. PC cells (Capan-1 and BxPC-3) underwent incubation with 5-aminolevulinic acid (5-ALA) or/and ultrasound (US) exposure (control, 5-ALA, US, and SDT groups), followed by measurement of cell apoptosis and autophagy. Specifically, cell viability, apoptosis, and the expression of apoptosis-related proteins (cleaved Caspase-3, Bax, and Bcl-2) were measured using CCK-8 assay, flow cytometry, and western blot analysis, respectively. The mitochondrial morphology was observed with the transmission electron microscopy, accompanied by the detection of autophagosome marker (LC3) co-located with Mito and the protein expression of LC3II/I. Before SDT treatment, the autophagy inhibitor 3-MA and the apoptosis inhibitor z-VAD were respectively added to PC cell cultures to evaluate the effects of autophagy inhibition on apoptosis and apoptosis inhibition on autophagy in PC cells. Results. Compared with the control group, cell viability was inhibited and cell apoptosis and autophagy were enhanced in the SDT group, while cell viability, autophagy, and apoptosis in the 5-ALA and US groups were not significantly changed. Moreover, 3-MA treatment inhibited autophagy and accelerated apoptosis, whereas z-VAD treatment reduced apoptosis but did not affect autophagy in PC cells. Conclusions. Autophagy was activated in SDT-treated PC cells, and inhibition of autophagy promoted cell apoptosis in PC cells

Summary of drug therapy to treat cognitive impairment-induced obstructive sleep apnea

Obstructive sleep apnea (OSA) is a severe sleep disorder associated with intermittent hypoxia and sleep fragmentation. Cognitive impairment is a signifi- cant and common OSA complication often described in such patients. The most commonly utilized methods in clinical OSA treatment are oral appliances and continuous positive airway pressure (CPAP). However, the current therapeutic methods for improving cognitive function could not achieve the expected efficacy in same patients. Therefore, further understanding the molecular mechanism behind cognitive dysfunction in OSA disease will provide new treatment methods and targets. This review briefly summarized the clinical manifestations of cognitive impairment in OSA disease. Moreover, the pathophysiological molecular mechanism of OSA was outlined. Our study concluded that both SF and IH could induce cognitive impairment by multiple signaling pathways, such as oxidative stress activation, inflammation, and apoptosis. However, there is a lack of effective drug therapy for cognitive impairment in OSA. Finally, the therapeutic potential of some novel compounds and herbal medicine was evaluated on attenuating cognitive impairment based on certain preclinical studies