Effect of Progesterone Combined with Low Molecular Weight Heparin Sodium in the Treatment of Recurrent Miscarriage

Objective: To analyze the effect of progesterone combined with low molecular weight heparin sodium in the treatment of recurrent miscarriage. Methods: A total of 68 patients with recurrent miscarriage admitted to our hospital within 1 year from 2022.04 to 2023.04 were selected as research subjects, and they were divided into control group (34 cases, treated with progesterone) and observation group (34 cases, treated with low molecular weight heparin sodium combined with progesterone) according to the random number table method. The treatment effects of the two groups were analyzed. Results: Both groups achieved certain results after treatment, but the coagulation indexes, sex hormone levels and delivery outcomes of the observation group were better than those in the control group after treatment with progesterone combined with low molecular weight heparin sodium (P<0.05). Conclusion: Progesterone combined with low molecular weight heparin sodium can effectively improve the coagulation effect, regulate the level of sex hormones, and improve the outcome of childbirth in patients with recurrent miscarriage

A Filled Function Method Dominated by Filter for Nonlinearly Global Optimization

This work presents a filled function method based on the filter technique for global optimization. Filled function method is one of the effective methods for nonlinear global optimization, since it can effectively find a better minimizer. Filter technique is applied to local optimization methods for its excellent numerical results. In order to optimize the filled function method, the filter method is employed for global optimizations in this method. A new filled function is proposed first, and then the algorithm and its properties are proved. The numerical results are listed at the end

Perpendicular magnetic anisotropy in conducting NiCo\u3csub\u3e2\u3c/sub\u3eO\u3csub\u3e4\u3c/sub\u3e films from spin-lattice coupling

High perpendicular magnetic anisotropy (PMA), a property needed for nanoscale spintronic applications, is rare in oxide conductors. We report the observation of a PMA up to 0.23 MJ/m3 in modestly strained (–0.3%) epitaxial NiCo2O4 films which are room-temperature ferrimagnetic conductors. Spin-lattice coupling manifested as magnetoelastic effect was found as the origin of the PMA. The in-plane x2-y2 states of Co on tetrahedral sites play crucial role in the magnetic anisotropy and spin-lattice coupling with an energy scale of 1 meV/f.u. The elucidation of the microscopic origin paves a way for engineering oxide conductors for PMA using metal/oxygen hybridizations

MSS-DepthNet: Depth Prediction with Multi-Step Spiking Neural Network

Event cameras are considered to have great potential for computer vision and robotics applications because of their high temporal resolution and low power consumption characteristics. However, the event stream output from event cameras has asynchronous, sparse characteristics that existing computer vision algorithms cannot handle. Spiking neural network is a novel event-based computational paradigm that is considered to be well suited for processing event camera tasks. However, direct training of deep SNNs suffers from degradation problems. This work addresses these problems by proposing a spiking neural network architecture with a novel residual block designed and multi-dimension attention modules combined, focusing on the problem of depth prediction. In addition, a novel event stream representation method is explicitly proposed for SNNs. This model outperforms previous ANN networks of the same size on the MVSEC dataset and shows great computational efficiency

Pharmacokinetics, tissue distribution, excretion, and metabolism of a novel antitumor agent, gambogenic acid, in rats

The plasma pharmacokinetics, tissue distribution, excretion, and metabolism of gambogenic acid (GNA), potential antitumor candidate, were investigated in rats. GNA showed linear pharmacokinetic characteristics in rats within the test dose (1, 2, and 4 mg/kg). The t1/2β was 40.38-41.16 min. GNA showed an extensive distribution into multiple tissues, and the bile excretion is the major pathway of excretion, accounting for 52.12 %. About 40 % of GNA might undergo metabolism in vivo and the main phase I metabolites of GNA may be 10-hydroxygambogenic acid and 9,10-epoxygambogenic acid.Colegio de Farmacéuticos de la Provincia de Buenos Aire