153 research outputs found
Steady and dynamic magnetic phase transitions in interacting quantum dots arrays coupled with leads
We apply the Hubbard model, non-equilibrium Green's function (NEGF) theory,
exact diagonalization (ED) and the hierarchical equations of motion (HEOM)
method to investigate abundant magnetic phase transitions in the 1D interacting
quantum dots arrays (QDA) sandwiched by non-interaction leads. The spin
polarization phase transitions are firstly studied with a mean-field
approximation. The many-body calculation of the ED method is then used to
verify such transitions. We find with the weak device-leading couplings, the
anti-ferromagnetic (AF) state only exists in the uniform odd-numbered QDA or
the staggered-hopping QDA systems. With increasing the coupling strength or the
bias potentials, there exists the magnetism-to non-magnetism phase transition.
With the spin-resolved HEOM method we also investigate the detailed dynamic
phase transition process of these lead-QDA-lead systems.Comment: 17 pages, 6 figure
A catalogue and statistical analysis for magnetic stars
Magnetic fields are significant in the structure and evolution of stars. We
present a comprehensive catalogue of 1784 known magnetic stars, detailing their
identifications, HD numbers, precise locations, spectral types, and averaged
quadratic effective magnetic fields among other important information. The
group comprises 177 O-type stars, 551 B-type stars, 520 A-type stars, 91 F-type
stars, 53 G-type stars, 61 K-type stars, 31 M-type stars, and an additional 300
stars whose spectral classification remains indeterminate. Our analysis
examines the statistical properties of these magnetic stars. The relative
integrated distribution function and number distribution function for all
magnetic stars of the same spectral type can be effectively approximated using
an exponential function of the averaged quadratic effective magnetic field. The
analysis further reveals that A and B-type stars possess the strongest mean
magnetic fields, indicating an easier detection of their magnetic fields.Comment: 36 pages, 11 figures, accepted 2023 July 11 by RA
Pan-cancer analysis of the prevalence and associated factors of lung metastasis and the construction of the lung metastatic classification system
This study first presents an analysis of the prevalence and associated factors of the lung metastasis (LM) database and then uses this analysis to construct an LM classification system. Using cancer patient data gathered from the surveillance, epidemiology, and end results (SEER) database, this study shows that the prevalence of LM is not consistent among different cancers; that is, the prevalence of LM ranges from 0.0013 [brain; 95% confidence interval (95% CI); 0.0010–0.0018] to 0.234 (“other digestive organs”; 95% CI; 0.221–0.249). This study finds that advanced age, poor grade, higher tumor or node stage, and metastases including bone, brain, and liver are positively related to LM occurrence, while female gender, income, marital status, and insured status are negatively related. Then, this study generates four categories from 58 cancer types based on prevalence and influence factors and satisfactorily validates these. This classification system reflects the LM risk of different cancers. It can guide individualized treatment and the management of these synchronous metastatic cancer patients and help clinicians better distribute medical resources
Effects of treatment with Astragalus Membranaceus on function of rat leydig cells
Background
Astragalus membranaceus (AM) is a Chinese traditional herb which has been reported to have broad positive effects on many diseases, including hepatitis, heart disease, diabetes and skin disease. AM can promote cell proliferation, increase the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx), and inhibit apoptosis by regulating the transcription of proto-oncogenes controlling cell death. While AM is included in some commercially available “testosterone boosting supplements”, studies directly testing ability of AM to modulate testosterone production are lacking. In the present study, we examined the effects of AM on Leydig cell function in vitro. Methods
Rat Leydig cells were purified and treated with AM at different concentrations (0 ÎĽg/mL, 10 ÎĽg/mL, 20 ÎĽg/mL, 50 ÎĽg/mL, 100 ÎĽg/mL and 150 ÎĽg/mL) and cell counting-8 (CCK-8) assay, Enzyme-linked immunosorbent assay, quantitative real time PCR and analysis of activities of SOD and GPx were done respectively. Results
Treatment with 100 μg/mL (P \u3c 0.05) and 150 μg/mL AM (P \u3c 0.01) significantly increased Leydig cell numbers. Treatment with AM (20 μg/mL, 50 μg/mL and 100 μg/mL) significantly increased testosterone production (P \u3c 0.01). In addition, increased Leydig cell SOD and GPx activities were observed in response to 20 μg/mL and 50 μg/mL AM treatment (P \u3c 0.01). Furthermore, expression of Bax mRNA was significantly decreased (P \u3c 0.01), and the ratio of Bcl-2/Bax mRNA was significantly increased in response to 20 μg/mL AM in the culture medium (P \u3c 0.05). Conclusions
Results supported a beneficial effect of AM on multiple aspects of rat Leydig cell function in vitro including testosterone production
Keyframe image processing of semantic 3D point clouds based on deep learning
With the rapid development of web technologies and the popularity of smartphones, users are uploading and sharing a large number of images every day. Therefore, it is a very important issue nowadays to enable users to discover exactly the information they need in the vast amount of data and to make it possible to integrate their large amount of image material efficiently. However, traditional content-based image retrieval techniques are based on images, and there is a “semantic gap” between this and people's understanding of images. To address this “semantic gap,” a keyframe image processing method for 3D point clouds is proposed, and based on this, a U-Net-based binary data stream semantic segmentation network is established for keyframe image processing of 3D point clouds in combination with deep learning techniques
The combined transarterial and transvenous onyx embolization of dural arteriovenous fistula of hypoglossal canal via the external jugular vein and facial vein: A case report
Dural arteriovenous fistulas of the hypoglossal canal (HCDAVFs) involving the anterior condylar confluence (ACC) and anterior condylar vein (ACV) are infrequent. Although transvenous embolization through the internal jugular vein (IJV) is the preferred treatment option for type I and II fistulas, it can be difficult if the IJV is unavailable. Here we report a rare case of HCDAVF in which the most common transvenous embolization access via IJV was not available. The patient underwent transarterial and transvenous onyx embolization. Transarterial embolization (TAE) aimed at controlling the arterial inflow and subsequently TVE was performed via the external jugular vein (EJV), the facial vein, the ophthalmic vein, the cavernous sinus, ACC, and ultimately to the fistula pouch. Complete obliteration of the HCDAVF was achieved without complications. We suggest that transvenous embolization (TVE) via the EJV and the facial vein can be effective in cases where trans-IJV is not possible
ACT001 improved cardiovascular function in septic mice by inhibiting the production of proinflammatory cytokines and the expression of JAK-STAT signaling pathway
Sepsis is a life-threatening multiple organ dysfunction syndrome (MODS) caused by a microbial infection that leads to high morbidity and mortality worldwide. Sepsis-induced cardiomyopathy (SIC) and coagulopathy promote the progression of adverse outcomes in sepsis. Here, we reported that ACT001, a modified compound of parthenolide, improved the survival of sepsis mice. In this work, we used cecal ligation and puncture (CLP) model to induce SIC. Transthoracic echocardiography and HE staining assays were adopted to evaluate the influence of ACT001 on sepsis-induced cardiac dysfunction. Our results showed that ACT001 significantly improved heart function and reduced SIC. Coagulation accelerates organ damage in sepsis. We found that ACT001 decreased blood clotting in the FeCl3-induced carotid artery thrombosis experiment. ACT001 also reduced the production of neutrophil extracellular traps (NETs). RNA-sequencing of heart tissues revealed that ACT001 significantly downregulated the expression of pro-inflammatory cytokines and the JAK-STAT signaling pathway. These results were confirmed with real-time PCR and ELISA. In summary, we found ACT001 rescued mice from septic shock by protecting the cardiovascular system. This was partially mediated by inhibiting pro-inflammatory cytokine production and down-regulating the JAK-STAT signaling
Clinical features, outcome and risk factors in cervical cancer patients after surgery for chronic radiation enteropathy
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