344 research outputs found
The gender wage gap in the public and private sectors in Canada
The Canadian labour market experienced a considerable decline in the male-female pay gap during years 1988 to 1992. After 1992, however, the gender wage gap decreased only slightly. This paper will study the issue of difference in the explained gender wage gap in both the public and the private sectors and will examine the components of change in the wage gap between 1991 and 1996. We measure and decompose the gender wage differentials into explained and unexplained parts separately for the public and private sectors in Canada for the census years 1991 and 1996, and compare changes in the earnings gap between 1991 and 1996 in both sectors. The analysis is based on Oaxaca decomposition and Juhn-Murphy-Pierce decomposition techniques. Results show that gender wage differentials are present in both sectors, although at a lower level in the public sector than in the private sector. In 1996, 67 percent of the wage gap is attributable to the unexplained part in the public sector, while in the private sector, this figure is 76 percent. Generally, males tend to have higher return to experience and more favorable occupation and industry distributions, which can account for the gender wage gap. Our findings also show that the overall gender wage gap decreases in both the public sector and the private sector between 1991 and 1996. This decrease is mainly attributed to the diminishing of the unexplained portion. In both the public and the private sectors, improvements in women’s wage-determining factors and ranking relative to those of men contributed to a narrowing of the gender wage gap
Looking through goal theories in language learning: A review on goal setting and achievement goal theory
A growing interest can be seen in the studies on the motivation related to second/foreign learning in recent decades. All in all, research verdicts designate that academic motivation plays a key function in the extent to which students are successful in their research. One of the dimensions of academic motivation is goal orientation, which accounts for why learners carry out achievement activities. This type of goal is indicative of the importance one attaches to success concerning a performance standard. Furthermore, goal setting is deemed as a significant cognitive interface that connects motivation to motivational behavior. Indeed, goal setting is an inseparable part of L2 learning that has caught the attention of many researchers. It functions as a booster of motivation and success in various fields. Goals render the activities purposeful, providing individuals with directions. Moreover, goal drives them to invest more resources and effort, pushing them to persevere in learning. The new versions of motivational theories emphasize social-cognitive components underlying motivated behavior. Therefore, they are more inclusive than traditional ones. Achievement goal theory (AGT) has been developed as a motivation-related theory in recent decades. This theory serves as an effective framework to account for motivation associated with social achievement and learning environments. It also deals with the outcomes concerning cognitive and behavioral aspects. Another theory related to motivation is the Goal setting theory, which functions as a cognitive mediator between motivation and second/foreign learning behavior. It also impacts the students’ application of strategies. Drawing on the recent conceptual developments, this review seeks to make a contribution to the related literature on theories of achievement goals, i.e., AGT and goal setting associated with the L2 context. Such a review has pedagogical implications for EFL stakeholders
Id2 complexes with the SNAG domain of Snai1 inhibiting Snai1-mediated repression of integrin beta4
The epithelial-mesenchymal transition (EMT) is a fundamental process that underlies development and cancer. Although the EMT involves alterations in the expression of specific integrins that mediate stable adhesion to the basement membrane, such as alpha6beta4, the mechanisms involved are poorly understood. Here, we report that Snai1 inhibits beta4 transcription by increasing repressive histone modification (trimethylation of histone H3 at K27 [H3K27Me3]). Surprisingly, Snai1 is expressed and localized in the nucleus in epithelial cells, but it does not repress beta4. We resolved this paradox by discovering that Id2 complexes with the SNAG domain of Snai1 on the beta4 promoter and constrains the repressive function of Snai1. Disruption of the complex by depleting Id2 resulted in Snai1-mediated beta4 repression with a concomitant increase in H3K27Me3 modification on the beta4 promoter. These findings establish a novel function for Id2 in regulating Snai1 that has significant implications for the regulation of epithelial gene expression
Hydrothermal Synthesis of SBA-15 Using Sodium Silicate Derived from Coal Gangue
Well-ordered SBA-15 was prepared with a hydrothermal route by sodium silicate derived from coal gangue. The as-prepared sample was analyzed by SAXRD, BET, TEM, and SEM, respectively. The results indicate that at a low hydrothermal temperature of 100∘C the well-ordered mesoporous SBA-15 could be synthesized. The surface area, pore volume, and pore size of the sample are 552 m2/g, 0.54 cm3/g, and 7.0 nm, respectively. It is suggested that coal gangue could be used in obtaining an Si source to prepare mesoporous materials, such as SBA-15
Availability, Pharmaceutics, Security, Pharmacokinetics, and Pharmacological Activities of Patchouli Alcohol
Patchouli alcohol (PA), a tricyclic sesquiterpene, is one of the critical bioactive ingredients and is mainly isolated from aerial part of Pogostemon cablin (known as guanghuoxiang in China) belonging to Labiatae. So far, PA has been widely applied in perfume industries. This review was written with the use of reliable information published between 1974 and 2016 from libraries and electronic researches including NCKI, PubMed, Reaxys, ACS, ScienceDirect, Springer, and Wiley-Blackwell, aiming at presenting comprehensive outline of security, pharmacokinetics, and bioactivities of PA and at further providing a potential guide in exploring the PA and its use in various medical fields. We found that PA maybe was a low toxic drug that was acquired numerously through vegetable oil isolation and chemical synthesis and its stability and low water dissolution were improved in pharmaceutics. It also possessed specific pharmacokinetic characteristics, such as two-compartment open model, first-order kinetic elimination, and certain biometabolism and biotransformation process, and was shown to have multiple biological activities, that is, immunomodulatory, anti-inflammatory, antioxidative, antitumor, antimicrobial, insecticidal, antiatherogenic, antiemetic, whitening, and sedative activity. However, the systematic evaluations of preparation, pharmaceutics, toxicology, pharmacokinetics, and bioactivities underlying molecular mechanisms of action also required further investigation prior to practices of PA in clinic
Probing Interface of Perovskite Oxide Using Surface-specific Terahertz Spectroscopy
The surface/interface species in perovskite oxides play an essential role in
many novel emergent physical phenomena and chemical processes. With low
eigen-energy in the terahertz region, such species at buried interfaces remain
poorly understood due to the lack of feasible experimental techniques. Here, we
show that vibrational resonances and two-dimensional electron gas at the
interface can be characterized using surface-specific nonlinear spectroscopy in
the terahertz range. This technique uses intra-pulse difference frequency
mixing (DFM) process, which is allowed only at surface/interface of a medium
with inversion symmetry. Sub-monolayer sensitivity can be achieved using the
state-of-the-art detection scheme for the terahertz emission from
surface/interface. As a demonstration, Drude-like nonlinear response from the
two-dimensional electron gas emerging at LaAlO3/SrTiO3 or Al2O3/ SrTiO3
interface was successfully observed. Meanwhile, the interfacial vibrational
spectrum of the ferroelectric soft mode of SrTiO3 at 2.8 THz was also obtained
that was polarized by the surface field in the interfacial region. The
corresponding surface/interface potential, which is a key parameter for
SrTiO3-based interface superconductivity and photocatalysis, can now be
determined optically via quantitative analysis on the polarized phonon
spectrum. The interfacial species with resonant frequencies in the THz region
revealed by our method provide more insights into the understanding of physical
properties of complex oxides.Comment: arXiv admin note: substantial text overlap with arXiv:2207.1461
Learning from Easy to Complex: Adaptive Multi-curricula Learning for Neural Dialogue Generation
Current state-of-the-art neural dialogue systems are mainly data-driven and
are trained on human-generated responses. However, due to the subjectivity and
open-ended nature of human conversations, the complexity of training dialogues
varies greatly. The noise and uneven complexity of query-response pairs impede
the learning efficiency and effects of the neural dialogue generation models.
What is more, so far, there are no unified dialogue complexity measurements,
and the dialogue complexity embodies multiple aspects of
attributes---specificity, repetitiveness, relevance, etc. Inspired by human
behaviors of learning to converse, where children learn from easy dialogues to
complex ones and dynamically adjust their learning progress, in this paper, we
first analyze five dialogue attributes to measure the dialogue complexity in
multiple perspectives on three publicly available corpora. Then, we propose an
adaptive multi-curricula learning framework to schedule a committee of the
organized curricula. The framework is established upon the reinforcement
learning paradigm, which automatically chooses different curricula at the
evolving learning process according to the learning status of the neural
dialogue generation model. Extensive experiments conducted on five
state-of-the-art models demonstrate its learning efficiency and effectiveness
with respect to 13 automatic evaluation metrics and human judgments.Comment: Accepted to AAAI 202
Pharmacological Activities of Patchouli Alcohol
Patchouli alcohol (PA), a tricyclic sesquiterpene, is one of the critical bioactive ingredients and is mainly isolated from aerial part of Pogostemon cablin (known as guanghuoxiang in China) belonging to Labiatae. So far, PA has been widely applied in perfume industries. This review was written with the use of reliable information published between 1974 and 2016 from libraries and electronic researches including NCKI, PubMed, Reaxys, ACS, ScienceDirect, Springer, and Wiley-Blackwell, aiming at presenting comprehensive outline of security, pharmacokinetics, and bioactivities of PA and at further providing a potential guide in exploring the PA and its use in various medical fields. We found that PA maybe was a low toxic drug that was acquired numerously through vegetable oil isolation and chemical synthesis and its stability and low water dissolution were improved in pharmaceutics. It also possessed specific pharmacokinetic characteristics, such as two-compartment open model, first-order kinetic elimination, and certain biometabolism and biotransformation process, and was shown to have multiple biological activities, that is, immunomodulatory, anti-inflammatory, antioxidative, antitumor, antimicrobial, insecticidal, antiatherogenic, antiemetic, whitening, and sedative activity. However, the systematic evaluations of preparation, pharmaceutics, toxicology, pharmacokinetics, and bioactivities underlying molecular mechanisms of action also required further investigation prior to practices of PA in clinic
High throughput Single-cell Cultivation on Microfluidic Streak Plates
This paper describes the microfluidic streak plate (MSP), a facile method for high-throughput microbial cell separation and cultivation in nanoliter sessile droplets. The MSP method builds upon the conventional streak plate technique by using microfluidic devices to generate nanoliter droplets that can be streaked manually or robotically onto petri dishes prefilled with carrier oil for cultivation of single cells. In addition, chemical gradients could be encoded in the droplet array for comprehensive dose-response analysis. The MSP method was validated by using single-cell isolation of Escherichia coli and antimicrobial susceptibility testing of Pseudomonas aeruginosa PAO1. The robustness of the MSP work flow was demonstrated by cultivating a soil community that degrades polycyclic aromatic hydrocarbons. Cultivation in droplets enabled detection of the richest species diversity with better coverage of rare species. Moreover, isolation and cultivation of bacterial strains by MSP led to the discovery of several species with high degradation efficiency, including four Mycobacterium isolates and a previously unknown fluoranthene-degrading Blastococcus species
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