基于OEC管理模式的护理环节质量控制在提高患者 满意度中的应用研究

Objective: Through the introduction of OEC management mode, build “be hospitalized- in the hospital – discharge”in each stage of scientific, humanized nursing quality management system, improve the patients' satisfaction degree. Methods:Through the pre discharged patients satisfaction telephone follow-up, analyze the key links of satisfaction, to establish the Humanized, scientific and rational management system based on the OEC management model, Modify and improve the work process and evaluation index that Influence the quality of patient satisfaction of nursing links, implemented on a pilot unit, the comparison between the experimental unit and non-pilot ward patient satisfaction. Results: Analyze of satisfaction before and after the implementation of the quality control management mode based on OEC mode: (1)pilot wards in after the implementation of self-satisfaction is significantly higher than before < 0.05), and non-pilot unit has no significant difference before and after the implementation of self-satisfaction in (P > 0.05); (2)the pilot unit and non-pilot unit, the discharged patients satisfaction was significantly higher than the latter (P < 0.05). Conclusion: The quality control of nursing process based on the OEC management mode can improve the patients' satisfaction degree significantly, that can be widely used in hospital nursing management.目的  通过引入OEC管理模式，构建患者“入院-院中-出院”各阶段科学性、人性化的护理环节质量管理体系，提高住院患者满意度。方法  通过前期出院患者满意度电话回访，分析影响满意度的重点环节，以OEC管理模式为基础，建立人性化、科学合理的环节管理制度，修改和完善患者满意度护理环节质量的工作流程和评价指标，在试点病房进行实施，比较试点病房与非试点病房之间患者满意度。结果  实施OEC管理模式环节质量控制前后满意度分析：（1）试点病房自身满意度在实施后明显高于实施前（P < 0.05），而非试点病房自身满意度在实施前后无明显差异（P > 0.05）；（2）试点病房与非试点病房之间比较，前者出院患者满意度明显高于后者（P < 0.05）。结论  基于OEC管理模式的护理环节质量控制能明显提高住院患者满意度，可以在医院护理管理中广泛推广运用

Comparison of the refractive error changes among young children in ten years interval

AIM: To compare the optometric examination results of myopic young children between those diagnosed in the period from 1998 to 2000 and those diagnosed in the period from 2008 to 2010; and to find out the causes of myopia and factors that worsen the condition, and suggest methods of its prevention and treatment.<p>METHODS: This study was a retrospective case study. We randomly selected sample from out-patient department register of cases and divided them into two main groups, ‘ten year before group'(TYBG)(1998/2000 year cases)and ‘ten years later group'(2008/2010 year cases)(TYLG). Each group was further subdivided into three sub-groups by age: under-six years old children group(CG), seven-twelve years old primary-school group(PSG)and thirteen-eighteen years old middle-school group(MSG). The optometric examination results were statistically analyzed.<p>RESULTS: The difference of the mean dioptre between the TYBG and TYLG was strongly statistically significant, also forward-lead trend of age when children suffered from myopia was found(<i>P<</i>0.01). There was a significant increase of dioptre among PSG and MSG in TYLG compared to TYBG(<i>P</i><0.01). After analyzing the relationship between dioptre and age, this study showed an increase of the proportion of myopia patients from 35.2% to 50.0% in PSG in ten years interval. This proportion decreases in MSG and remains stable in CG. All cases had been divided into slight myopia, medium myopia and high myopia, depending on their own myopia dioptre. The biggest difference of myopia dioptre were seen in MSG where the proportion of medium myopia patients increased 11.4% and high myopia patients increased 7.9% in TYLG.<p>CONCLUSION: Our study shows that the age of getting myopia was forward lead, the dioptre increases by 1.00 degree and the prevalence of myopia is increasing gradually. This situation may due to the modern life style and changes of living standard of the population. Therefore, prevention of myopia should concentrate more on younger children at kindergarten and primary school stage students

Myricetin ameliorates cognitive impairment in 3×Tg Alzheimer’s disease mice by regulating oxidative stress and tau hyperphosphorylation

Background: Alzheimer's disease is characterized by abnormal β-amyloid (Aβ) plaque accumulation, tau hyperphosphorylation, reactive oxidative stress, mitochondrial dysfunction and synaptic loss. Myricetin, a dietary flavonoid, has been shown to exert neuroprotective effects in vitro and in vivo. Here, we aimed to elucidate the mechanism and pathways involved in the protective effect of myricetin. Methods: The effect of myricetin was assessed on Aβ42 oligomer-treated neuronal SH-SY5Y cells and in 3×Tg mice. Behavioral tests were performed to assess the cognitive effects of myricetin (14 days, ip) in 3×Tg mice. The levels of beta-amyloid precursor protein (APP), synaptic and mitochondrial proteins, glycogen synthase kinase3β (GSK3β) and extracellular regulated kinase (ERK) 2 were assessed via Western blotting. Flow cytometry assays, immunofluorescence staining, and transmission electron microscopy were used to assess mitochondrial dysfunction and reactive oxidative stress. Results: We found that, compared with control treatment, myricetin treatment improved spatial cognition and learning and memory in 3×Tg mice. Myricetin ameliorated tau phosphorylation and the reduction in pre- and postsynaptic proteins in Aβ42 oligomer-treated neuronal SH-SY5Y cells and in 3×Tg mice. In addition, myricetin reduced reactive oxygen species generation, lipid peroxidation, and DNA oxidation, and rescued mitochondrial dysfunction via the associated GSK3β and ERK 2 signalling pathways. Conclusions: This study provides new insight into the neuroprotective mechanism of myricetin in vitro in cell culture and in vivo in a mouse model of Alzheimer’s disease

2,2′-[(1E)-3-Phenyl­prop-2-ene-1,1-di­yl]bis­(3-hy­droxy-5,5-dimethyl­cyclo­hex-2-en-1-one)

In the title mol­ecule, C25H30O4, the two cyclo­hexene rings adopt envelope conformations. The two hy­droxy groups are involved in the formation of intra­molecular O—H⋯O hydrogen bonds. In the crystal structure, weak inter­molecular C—H⋯O hydrogen bonds link mol­ecules related by translation along the axis a into chains

Model of a multiverse providing the dark energy of our universe

It is shown that the dark energy presently observed in our universe can be regarded as the energy of a scalar field driving an inflation-like expansion of a multiverse with ours being a subuniverse among other parallel universes. A simple model of this multiverse is elaborated: Assuming closed space geometry, the origin of the multiverse can be explained by quantum tunneling from nothing; subuniverses are supposed to emerge from local fluctuations of separate inflation fields. The standard concept of tunneling from nothing is extended to the effect that in addition to an inflationary scalar field, matter is also generated, and that the tunneling leads to an (unstable) equilibrium state. The cosmological principle is assumed to pertain from the origin of the multiverse until the first subuniverses emerge. With increasing age of the multiverse, its spatial curvature decays exponentially so fast that, due to sharing the same space, the flatness problem of our universe resolves by itself. The dark energy density imprinted by the multiverse on our universe is time-dependent, but such that the ratio $w{=}\varrho/(c^2p)$ of its mass density and pressure (times $c^2$) is time-independent and assumes a value $-1{+}\epsilon$ with arbitrary $\epsilon{>}0$. $\epsilon$ can be chosen so small, that the dark energy model of this paper can be fitted to the current observational data as well as the cosmological constant model.Comment: 32 pages, 4 figure

N-(2-Chloro­benzo­yl)-N′-(3-pyrid­yl)thio­urea

In the mol­ecule of the title compound, C13H10ClN3OS, the dihedral angles between the plane through the thio­urea group and the pyridine and benzene rings are 53.08 (3) and 87.12 (3)°, respectively. The mol­ecules are linked by inter­molecular N—H⋯N hydrogen-bonding inter­actions to form a supra­molecular chain structure along the a axis. An intra­mol­ecular N—H⋯O hydrogen bond is also present