A Mathematical Model for Thermosensitive Liposomal Delivery of Doxorubicin to Solid Tumour

Peer reviewedPublisher PD

The effect of tumour size on drug transport and uptake in 3-D tumour models reconstructed from magnetic resonance images

This work was partially funded by the UK Engineering and Physics Sciences Research Council (EP/I001700/1) to XYX. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

Cooperative Multi-Type Multi-Agent Deep Reinforcement Learning for Resource Management in Space-Air-Ground Integrated Networks

The Space-Air-Ground Integrated Network (SAGIN), integrating heterogeneous devices including low earth orbit (LEO) satellites, unmanned aerial vehicles (UAVs), and ground users (GUs), holds significant promise for advancing smart city applications. However, resource management of the SAGIN is a challenge requiring urgent study in that inappropriate resource management will cause poor data transmission, and hence affect the services in smart cities. In this paper, we develop a comprehensive SAGIN system that encompasses five distinct communication links and propose an efficient cooperative multi-type multi-agent deep reinforcement learning (CMT-MARL) method to address the resource management issue. The experimental results highlight the efficacy of the proposed CMT-MARL, as evidenced by key performance indicators such as the overall transmission rate and transmission success rate. These results underscore the potential value and feasibility of future implementation of the SAGIN

A pilot study of aortic hemodynamics before and after thoracic endovascular repair with a double-branched endograft

This work was partially supported by Bolton Medical, Sunrise, Florida, US. The authors declare that although Bolton Medical supported this study, the funding company had no control, input or influence on the study design, data analysis or publications.Peer reviewedPublisher PD

Federated PAC-Bayesian Learning on Non-IID data

Existing research has either adapted the Probably Approximately Correct (PAC) Bayesian framework for federated learning (FL) or used information-theoretic PAC-Bayesian bounds while introducing their theorems, but few considering the non-IID challenges in FL. Our work presents the first non-vacuous federated PAC-Bayesian bound tailored for non-IID local data. This bound assumes unique prior knowledge for each client and variable aggregation weights. We also introduce an objective function and an innovative Gibbs-based algorithm for the optimization of the derived bound. The results are validated on real-world datasets

A Preliminary Evaluation of ChatGPT for Zero-shot Dialogue Understanding

Zero-shot dialogue understanding aims to enable dialogue to track the user's needs without any training data, which has gained increasing attention. In this work, we investigate the understanding ability of ChatGPT for zero-shot dialogue understanding tasks including spoken language understanding (SLU) and dialogue state tracking (DST). Experimental results on four popular benchmarks reveal the great potential of ChatGPT for zero-shot dialogue understanding. In addition, extensive analysis shows that ChatGPT benefits from the multi-turn interactive prompt in the DST task but struggles to perform slot filling for SLU. Finally, we summarize several unexpected behaviors of ChatGPT in dialogue understanding tasks, hoping to provide some insights for future research on building zero-shot dialogue understanding systems with Large Language Models (LLMs).Comment: Technical Repor

Exploring Energy-based Language Models with Different Architectures and Training Methods for Speech Recognition

Energy-based language models (ELMs) parameterize an unnormalized distribution for natural sentences and are radically different from popular autoregressive language models (ALMs). As an important application, ELMs have been successfully used as a means for calculating sentence scores in speech recognition, but they all use less-modern CNN or LSTM networks. The recent progress in Transformer networks and large pretrained models such as BERT and GPT2 opens new possibility to further advancing ELMs. In this paper, we explore different architectures of energy functions and different training methods to investigate the capabilities of ELMs in rescoring for speech recognition, all using large pretrained models as backbones.Comment: Accepted into INTERSPEECH 202

Ref-NMS: Breaking Proposal Bottlenecks in Two-Stage Referring Expression Grounding

The prevailing framework for solving referring expression grounding is based on a two-stage process: 1) detecting proposals with an object detector and 2) grounding the referent to one of the proposals. Existing two-stage solutions mostly focus on the grounding step, which aims to align the expressions with the proposals. In this paper, we argue that these methods overlook an obvious mismatch between the roles of proposals in the two stages: they generate proposals solely based on the detection confidence (i.e., expression-agnostic), hoping that the proposals contain all right instances in the expression (i.e., expression-aware). Due to this mismatch, current two-stage methods suffer from a severe performance drop between detected and ground-truth proposals. To this end, we propose Ref-NMS, which is the first method to yield expression-aware proposals at the first stage. Ref-NMS regards all nouns in the expression as critical objects, and introduces a lightweight module to predict a score for aligning each box with a critical object. These scores can guide the NMS operation to filter out the boxes irrelevant to the expression, increasing the recall of critical objects, resulting in a significantly improved grounding performance. Since Ref- NMS is agnostic to the grounding step, it can be easily integrated into any state-of-the-art two-stage method. Extensive ablation studies on several backbones, benchmarks, and tasks consistently demonstrate the superiority of Ref-NMS. Codes are available at: https://github.com/ChopinSharp/ref-nms.Comment: Appear in AAAI 2021, Codes are available at: https://github.com/ChopinSharp/ref-nm

Spin chirality fluctuation in two-dimensional ferromagnets with perpendicular anisotropy

Non-coplanar spin textures with scalar spin chirality can generate effective magnetic field that deflects the motion of charge carriers, resulting in topological Hall effect (THE), a powerful probe of the ground state and low-energy excitations of correlated systems. However, spin chirality fluctuation in two-dimensional ferromagnets with perpendicular anisotropy has not been considered in prior studies. Herein, we report direct evidence of universal spin chirality fluctuation by probing the THE above the transition temperatures in two different ferromagnetic ultra-thin films, SrRuO$_3$ and V doped Sb$_2$Te$_3$. The temperature, magnetic field, thickness, and carrier type dependences of the THE signal, along with our Monte-Carlo simulations, unambiguously demonstrate that the spin chirality fluctuation is a universal phenomenon in two-dimensional Ising ferromagnets. Our discovery opens a new paradigm of exploring the spin chirality with topological Hall transport in two-dimensional magnets and beyondComment: accepted by nature material