A Tubular Flexible Triboelectric Nanogenerator with a Superhydrophobic Surface for Human Motion Detecting

The triboelectric nanogenerator (TENG) is a newly arisen technology for mechanical energy harvesting from the environment, such as raindrops, wind, tides, and so on. It has attracted widespread attention in flexible electronics to serve as self-powered sensors and energy-harvesting devices because of its flexibility, durability, adaptability, and multi-functionalities. In this work, we fabricated a tubular flexible triboelectric nanogenerator (TF-TENG) with energy harvesting and human motion monitoring capabilities by employing polydimethylsiloxane (PDMS) as construction material, and fluorinated ethylene propylene (FEP) films coated with Cu as the triboelectric layer and electrode, serving in a free-standing mode. The tube structure has excellent stretchability that can be stretched up to 400%. Modifying the FEP films to obtain a superhydrophobic surface, the output performance of TF-TENG was increased by at least 100% compared to an untreated one. Finally, as the output of TF-TENG is sensitive to swing angle and frequency, demonstration of real-time monitoring of human motion state was realized when a TF-TENG was worn on the wrist

Genome-Wide Identification and Characterization of the Medium-Chain Dehydrogenase/Reductase Superfamily of <i>Trichosporon asahii</i> and Its Involvement in the Regulation of Fluconazole Resistance

The medium-chain dehydrogenase/reductase (MDR) superfamily contains many members that are widely present in organisms and play important roles in growth, metabolism, and stress resistance but have not been studied in Trichosporon asahii. In this study, bioinformatics and RNA sequencing methods were used to analyze the MDR superfamily of T. asahii and its regulatory effect on fluconazole resistance. A phylogenetic tree was constructed using Saccharomyces cerevisiae, Candida albicans, Cryptococcus neoformans, and T. asahii, and 73 MDRs were identified, all of which contained NADPH-binding motifs. T. asahii contained 20 MDRs that were unevenly distributed across six chromosomes. T. asahii MDRs (TaMDRs) had similar 3D structures but varied greatly in their genetic evolution at different phylum levels. RNA-seq and gene expression analyses revealed that the fluconazole-resistant T. asahii strain upregulates xylitol dehydrogenase, and downregulated alcohol dehydrogenase and sorbitol dehydrogenase concluded that the fluconazole-resistant T. asahii strain was less selective toward carbon sources and had higher adaptability to the environment. Overall, our study contributes to our understanding of TaMDRs, providing a basis for further analysis of the genes associated with drug resistance in T. asahii

Data from: Effects of stand age, richness and density on productivity in subtropical forests in China

1. Forest productivity may be determined not only by biodiversity but also by environmental factors and stand structure attributes. However, the relative importance of these factors in determining productivity is still controversial for subtropical forests. 2. Based on a large dataset from 600 permanent forest inventory plots across subtropical China, we examined the relationship between biodiversity and forest productivity and tested whether stand structural attributes (stand density in terms of trees per ha, age and tree size) and environmental factors (climate and site conditions) had larger effects on productivity. Furthermore, we quantified the relative importance of environmental factors, stand structure and diversity in determining forest productivity. 3. Diversity, together with stand structure and site conditions, regulated the variability in forest productivity. The relationship between diversity and forest productivity did not vary along environmental gradients. Stand density and age were more important modulators of forest productivity than diversity. 4. Synthesis. Diversity had significant and positive effects on productivity in species-rich subtropical forests, but the effects of stand density and age were also important. Our work highlights that while biodiversity conservation is often important, the regulation of stand structure can be even more important to maintain high productivity in subtropical forests

Management and outcomes of gastric leak after sleeve gastrectomy: results from the 2010-2020 national registry

Abstract. Background:. Management of gastric leak after sleeve gastrectomy (SG) is challenging due to its unpredictable outcomes. We aimed to summarize the characteristics of SG leaks and analyze interventions and corresponding outcomes in a real-world setting. Methods:. To retrospectively review of 15,721 SG procedures from 2010 to 2020 based on a national registry. A cumulative sum analysis was used to identify a fitting curve of gastric leak rate. The Kaplan-Meier method and log-rank tests were performed to calculate and compare the probabilities of relevant outcomes. The logistic regression analysis was conducted to determine the predictors of acute leaks. Results:. A total of 78 cases of SG leaks were collected with an incidence of 0.5% (78/15,721) from this registry (6 patients who had the primary SG in non-participating centers). After accumulating 260 cases in a bariatric surgery center, the leak rate decreased to a stably low value of under 1.17%. The significant differences presented in sex, waist circumference, and the proportion of hypoproteinemia and type 2 diabetes at baseline between patients with SG leak and the whole registry population (P = 0.005, = 0.026, 50%, whereas the cumulative healing probability in the patients who required surgical treatment was significantly lower than those requring non-surgical treatment (P = 0.013). Precise dissection in the His angle area was independently associated with a lower acute leak rate, whereas preservation ≥2 cm distance from the His angle area was an independent risk factor. Conclusions:. Male sex, elevated waist circumference, hypoproteinaemia, and type 2 diabetes are risk factors of gastric leaks after SG. Optimizing surgical techniques, including precise dissection of His angle area and preservation of smaller gastric fundus, should be suggested to prevent acute leaks