PypeR, A Python Package for Using R in Python

This article describes PypeR, a Python package which allows the R language to be called in Python using the pipe communication method. By running R through pipe, the Python program gains flexibility in sub-process controls, memory control, and portability across popular operating system platforms, including Windows, GNU Linux and Mac OS X. PypeR can be downloaded at http://rinpy.sourceforge.net/

Glass matrix composite material prepared with waste foundry sand

The technology of glass matrix of the composite material manufactured through a sintering process and using waste foundry sand and waste glass as the main raw materials was studied. The effects of technological factors on the performance of this material were studied. The results showed that this composite material is formed with glass as matrix, core particulate as strengthening material, it has the performance of glass and ceramics, and could be used to substitute for stone

Evaluation of the Role of Functional Constraints on the Integrity of an Ultraconserved Region in the Genus Drosophila

Why gene order is conserved over long evolutionary timespans remains elusive. A common interpretation is that gene order conservation might reflect the existence of functional constraints that are important for organismal performance. Alteration of the integrity of genomic regions, and therefore of those constraints, would result in detrimental effects. This notion seems especially plausible in those genomes that can easily accommodate gene reshuffling via chromosomal inversions since genomic regions free of constraints are likely to have been disrupted in one or more lineages. Nevertheless, no empirical test has been performed to this notion. Here, we disrupt one of the largest conserved genomic regions of the Drosophila genome by chromosome engineering and examine the phenotypic consequences derived from such disruption. The targeted region exhibits multiple patterns of functional enrichment suggestive of the presence of constraints. The carriers of the disrupted collinear block show no defects in their viability, fertility, and parameters of general homeostasis, although their odorant perception is altered. This change in odorant perception does not correlate with modifications of the level of expression and sex bias of the genes within the genomic region disrupted. Our results indicate that even in highly rearranged genomes, like those of Diptera, unusually high levels of gene order conservation cannot be systematically attributed to functional constraints, which raises the possibility that other mechanisms can be in place and therefore the underpinnings of the maintenance of gene organization might be more diverse than previously thought

Effects of Ultra-early Intervention on Gross Motor Function in Neonates with Hypoglycemic Brain Injury

Objective : To investigate the effect of ultra-early intervention on gross motor function of neonates with hypoglycemic brain injury and evaluate the application value. Methods: we choose thirty four children with hypoglycemic brain injury who hospitalized in the neonatology department of Tai'an City central hospital from January 2017 to December 2019. They were randomly divided into conventional treatment group and ultra-early intervention group, each with 17 people. The conventional treatment group received conventional treatment. In addition to conventional treatment, the ultra-early intervention group was given ultra-early intervention . When two groups of children's corrected gestational age at 40 weeks, 42 weeks and 44 weeks, they need to be tested for NBNA neonatal neurobehavioral testing, Alberta Infant Exercise Scale (AIMS) assessment and general exercise quality assessment (GMs ). Results: When the child's corrected gestational age is 40 weeks, there is no significant difference in the scores of NBNA and AIMS between the ultra-early intervention group and the conventional treatment group; When the child's corrected gestational age is 42 weeks, the NBNA and AIMS scores of the ultra-early intervention group are higher than those of the conventional treatment group, but there is no statistical significance; When the child's corrected gestational age is 44 weeks, the ultra-early intervention group had higher NBNA and AIMS scores than the conventional treatment group, which was statistically  significant (P<0. 05). Conclusion: After ultra-early intervention, the development level of gross motor in the ultra-early intervention group was significantly higher than that in the conventional treatment group. Ultra early intervention has obvious effect on the improvement of gross motor function in neonates with hypoglycemic brain injury