68 research outputs found
Extreme Learning Machine-Assisted Solution of Biharmonic Equations via Its Coupled Schemes
Obtaining the solutions of partial differential equations based on various
machine learning methods has drawn more and more attention in the fields of
scientific computation and engineering applications. In this work, we first
propose a coupled Extreme Learning Machine (called CELM) method incorporated
with the physical laws to solve a class of fourth-order biharmonic equations by
reformulating it into two well-posed Poisson problems. In addition, some
activation functions including tangent, gauss, sine, and trigonometric
(sin+cos) functions are introduced to assess our CELM method. Notably, the sine
and trigonometric functions demonstrate a remarkable ability to effectively
minimize the approximation error of the CELM model. In the end, several
numerical experiments are performed to study the initializing approaches for
both the weights and biases of the hidden units in our CELM model and explore
the required number of hidden units. Numerical results show the proposed CELM
algorithm is high-precision and efficient to address the biharmonic equation in
both regular and irregular domains
Review of latent thermal energy storage systems for solar air-conditioning systems
Solar air-conditioning is an important approach to satisfy the high demand for cooling given the global energy situation. The application of phase-change materials (PCMs) in a thermal storage system is a way to address temporary power problems of solar air-conditioning systems. This paper reviews the selection, strengthening, and application of PCMs and containers in latent thermal storage system for solar air-conditioning systems. The optimization of PCM container geometry is summarized and analyzed. The hybrid enhancement methods for PCMs and containers, and the cost assessment of latent thermal storage system are discussed. The more effective heat transfer enhancement using PCMs was found to mainly involve micro-nano additives. Combinations of fins and nanoadditives, nanoparticles and metal foam are the main hybrid strengthening method. However, the thermal storage effect of hybrid strengthening is not necessarily better than single strengthening. At the same time, the latent thermal storage unit has less application in the field of solar air-conditioning systems, especially regarding heat recovery, because of its cost and thermal storage time. The integration of latent thermal storage units and solar air-conditioning components, economic analysis of improvement technology, and quantitative studies on hybrid improvement are potential research directions in the future
Chromosome 2p14 Is Linked to Susceptibility to Leprosy
BACKGROUND: A genetic component to the etiology of leprosy is well recognized but the mechanism of inheritance and the genes involved are yet to be fully established. METHODOLOGY: A genome-wide single nucleotide polymorphism (SNP) based linkage analysis was carried out using 23 pedigrees, each with 3 to 7 family members affected by leprosy. Multipoint parametric and non-parametric linkage analyses were performed using MERLIN 1.1.1. PRINCIPAL FINDINGS: Genome-wide significant evidence for linkage was identified on chromosome 2p14 with a heterogeneity logarithm of odds (HLOD) score of 3.51 (rs1106577) under a recessive model of inheritance, while suggestive evidence was identified on chr.4q22 (HLOD 2.92, rs1349350, dominant model), chr. 8q24 (HLOD 2.74, rs1618523, recessive model) and chr.16q24 (HLOD 1.93, rs276990 dominant model). Our study also provided moderate evidence for a linkage locus on chromosome 6q24-26 by non-parametric linkage analysis (rs6570858, LOD 1.54, p = 0.004), overlapping a previously reported linkage region on chromosome 6q25-26. CONCLUSION: A genome-wide linkage analysis has identified a new linkage locus on chromosome 2p14 for leprosy in Pedigrees from China
Characterization of the "deqi" response in acupuncture
<p>Abstract</p> <p>Background</p> <p>Acupuncture stimulation elicits <it>deqi</it>, a composite of unique sensations that is essential for clinical efficacy according to traditional Chinese medicine (TCM). There is lack of adequate experimental data to indicate what sensations comprise <it>deqi</it>, their prevalence and intensity, their relationship to acupoints, how they compare with conventional somatosensory or noxious response. The objective of this study is to provide scientific evidence on these issues and to characterize the nature of the <it>deqi phenomenon </it>in terms of the prevalence of sensations as well as the uniqueness of the sensations underlying the <it>deqi </it>experience.</p> <p>Methods</p> <p>Manual acupuncture was performed at LI4, ST36 and LV3 on the extremities in randomized order during fMRI in 42 acupuncture naïve healthy adult volunteers. Non-invasive tactile stimulation was delivered to the acupoints by gentle tapping with a von Frey monofilament prior to acupuncture to serve as a sensory control. At the end of each procedure, the subject was asked if each of the sensations listed in a questionnaire or any other sensations occurred during stimulation, and if present to rate its intensity on a numerical scale of 1–10. Statistical analysis including paired t-test, analysis of variance, Spearman's correlation and Fisher's exact test were performed to compare responses between acupuncture and sensory stimulation.</p> <p>Results</p> <p>The <it>deqi </it>response was elicited in 71% of the acupuncture procedures compared with 24% for tactile stimulation when thresholded at a minimum total score of 3 for all the sensations. The frequency and intensity of individual sensations were significantly higher in acupuncture. Among the sensations typically associated with <it>deqi</it>, aching, soreness and pressure were most common, followed by tingling, numbness, dull pain, heaviness, warmth, fullness and coolness. Sharp pain of brief duration that occurred in occasional subjects was regarded as inadvertent noxious stimulation. The most significant differences in the <it>deqi </it>sensations between acupuncture and tactile stimulation control were observed with aching, soreness, pressure and dull pain. Consistent with its prominent role in TCM, LI4 showed the most prominent response, the largest number of sensations as well as the most marked difference in the frequency and intensity of aching, soreness and dull pain between acupuncture and tactile stimulation control. Interestingly, the dull pain generally preceded or occurred in the absence of sharp pain in contrast to reports in the pain literature. An approach to summarize a sensation profile, called the <it>deqi composite</it>, is proposed and applied to explain differences in <it>deqi </it>among acupoints.</p> <p>Conclusion</p> <p>The complex pattern of sensations in the <it>deqi </it>response suggests involvement of a wide spectrum of myelinated and unmyelinated nerve fibers, particularly the slower conducting fibers in the tendinomuscular layers. The study provides scientific data on the characteristics of the <it>'deqi' </it>response in acupuncture and its association with distinct nerve fibers. The findings are clinically relevant and consistent with modern concepts in neurophysiology. They can provide a foundation for future studies on the <it>deqi </it>phenomenon.</p
The Overseeing Mother: Revisiting the Frontal-Pose Lady in the Wu Family Shrines in Second Century China
Located in present-day Jiaxiang in Shandong province, the Wu family shrines built during the second century in the Eastern Han dynasty (25–220) were among the best-known works in Chinese art history. Although for centuries scholars have exhaustively studied the pictorial programs, the frontal-pose female image situated on the second floor of the central pavilion carved at the rear wall of the shrines has remained a question. Beginning with the woman’s eyes, this article demonstrates that the image is more than a generic portrait (“hard motif ”), but rather represents “feminine overseeing from above” (“soft motif ”). This synthetic motif combines three different earlier motifs – the frontal-pose hostess enjoying entertainment, the elevated spectator, and the Queen Mother of the West. By creatively fusing the three motifs into one unity, the Jiaxiang artists lent to the frontal-pose lady a unique power: she not only dominated the center of the composition, but also, like a divine being, commanded a unified view of the surroundings on the lofty building, hence echoing the political reality of the empress mother’s “overseeing the court” in the second century during Eastern Han dynasty
Solving a class of multi-scale elliptic PDEs by means of Fourier-based mixed physics informed neural networks
Deep neural networks have received widespread attention due to their
simplicity and flexibility in the fields of engineering and scientific
calculation. In this work, we probe into solving a class of elliptic Partial
Differential Equations (PDEs) with multiple scales by means of Fourier-based
mixed physics informed neural networks(dubbed FMPINN), the solver of FMPINN is
configured as a multi-scale deep neural networks. Unlike the classical PINN
method, a dual (flux) variable about the rough coefficient of PDEs is
introduced to avoid the ill-condition of neural tangent kernel matrix that
resulted from the oscillating coefficient of multi-scale PDEs. Therefore, apart
from the physical conservation laws, the discrepancy between the auxiliary
variables and the gradients of multi-scale coefficients is incorporated into
the cost function, then obtaining a satisfactory solution of PDEs by minimizing
the defined loss through some optimization methods. Additionally, a
trigonometric activation function is introduced for FMPINN, which is suited for
representing the derivatives of complex target functions. Handling the input
data by Fourier feature mapping, it will effectively improve the capacity of
deep neural networks to solve high-frequency problems. Finally, by introducing
several numerical examples of multi-scale problems in various dimensional
Euclidean spaces, we validate the efficiency and robustness of the proposed
FMPINN algorithm in both low-frequency and high-frequency oscillation cases
Bank erosion process and distribution along channel caused by multiple debris flow surges
<p>This dataset contains point cloud data and Excel table data, which together describe the bank retreat process of 5 types of bank soils caused by multiple debris flow surges</p>
Adaptive Weight Multi-channel Matching Pursuit Algorithm-Based Strong Shielding Removal Method
The strata with large impedance differences are presented as strong amplitude seismic events on the seismic profile, which obscure useful information of nearby reservoirs and need interpretive target processing to remove the strong shielding. Therefore, this study proposes a multi-channel matching pursuit algorithm based on adaptive weight to remove strong shielding. Moreover, to address the problem of poor matching accuracy and spatial continuity of normal multi-channel matching pursuit at area where strong tectonic changes occur, a multi-channel matching pursuit de-strong shielding method based on adaptive weights is proposed. First, we used the layer structure information to flatten the strong reflection layer locally to weaken the influence of stratigraphic structure changes on the extraction of the strong reflection layer. Subsequently, we introduced a correlation coefficient between adjacent seismic traces and the central trace as the weight of multi trace averaging, which improved the stability and lateral continuity of the matching results. The result analysis of model processing tests and practical seismic data application shows that the proposed method can effectively strip the strong reflections and highlight the effective reservoir information; the well seismic match degree is significantly improved with higher matching accuracy, better spatial continuity, and better striping effect than those of the conventional matching pursuit algorithm
- …