732 research outputs found
Responsabilidad ética de la industria farmacéutica sobre la inversión en investigación de las enfermedades olvidadas. Propuesta de mejora.
Millonesdepersonassufrenomuerendebidoalasenfermedadesolvidadas.Personalmentesostengoquelaindustriafarmacéuticadeberíainvertirmásdeloqueactualmentehaceparacombatirlas.Enesteartículosediscute,desdelaperspectivaética,lamayorimplicaciónquelaindustriafarmacéuticadebetenerconlainvestigaciónfrentealasenfermedadesolvidadas,comparandomipropuestaaotrosesquemasalternativoscomolosdePogge,ReissodeWinter.
Geochemical exploration in the Montseny Mountains (NE Spain)
A five year program of systematic multi-element geochemical exploration of the Catalonian Coastal Ranges has been initiated by the Geological Survey of Autonomic Government of Catalonia (Generalitat de Catalunya) and the Department of Geological and Geophysical Exploration (University of Barcelona). This paper reports the first stage results of this regional survey, covering an area of 530 km2 in the Montseny Mountains, NE of Barcelona (Spain). Stream sediments for metals and stream waters for fluoride were chosen because of the regional characteristics. Four target areas for future tactic survey were recognized after the prospect. The most important is a 40 km* zone in the Canoves-Vilamajor area, with high base metal values accompanied by Cd, Ni, Co, As and Sb anomalie
Combining low-code programming and SDL-based modeling with snap! in the industry 4.0 context
© 2021 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.One of the main challenges to implement Industry 4.0 technologies within the industrial fabric is the lack of suitable concrete models and tools that demonstrate the potential benefits of embracing the digital transformation process. To overcome this challenge, over the past years, various Industry 4.0 automation and robotics providers have presented solutions based on visual block programming languages, which follow an emerging low-code approach to reduce the entry barriers of digital technologies. However, block-based low-code tools typically lack the formality introduced by specification languages, limiting their ability to model the industrial processes formally. Taking this into account, in this article, we present the combination of specification languages and visual block programming languages to enable industrial users to test and/or build their own Digital Twin models at a suitable abstraction level and with low entry barriers. In particular, we combine SDL and Snap! to create SDL4Snap!, an opensource and web-based tool that facilitates the implementation and validation of Digital Twin prototypes. Overall, the resulting tool has the potential to reduce the entry barrier to Digital Twins in small and medium enterprises, which are part of the late majority and laggard groups regarding the adoption of digital technologies in the context of Industry 4.0.Peer ReviewedPostprint (published version
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