29,514 research outputs found
Microwave-induced resistance oscillations in a back-gated GaAs quantum well
We performed effective mass measurements employing microwave-induced
resistance oscillation in a tunable-density GaAs/AlGaAs quantum well. Our main
result is a clear observation of an effective mass increase with decreasing
density, in general agreement with earlier studies which investigated the
density dependence of the effective mass employing Shubnikov- de Haas
oscillations. This finding provides further evidence that microwave-induced
resistance oscillations are sensitive to electron-electron interactions and
offer a convenient and accurate way to obtain the effective mass.Comment: 4 pages, 4 figure
Analysis and Verification of Service Interaction Protocols - A Brief Survey
Modeling and analysis of interactions among services is a crucial issue in
Service-Oriented Computing. Composing Web services is a complicated task which
requires techniques and tools to verify that the new system will behave
correctly. In this paper, we first overview some formal models proposed in the
literature to describe services. Second, we give a brief survey of verification
techniques that can be used to analyse services and their interaction. Last, we
focus on the realizability and conformance of choreographies.Comment: In Proceedings TAV-WEB 2010, arXiv:1009.330
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HSV-2 Infection of Human Genital Epithelial Cells Upregulates TLR9 Expression Through the SP1/JNK Signaling Pathway
It is known that herpes simplex virus type 2 (HSV-2) triggers the activation of Toll-like receptor (TLR) 9 signaling pathway and the consequent production of antiviral cytokines in dendritic cells. However, the impact of HSV-2 infection on TLR9 expression and signaling in genital epithelial cells, the primary HSV-2 targets, has yet to be determined. In the current study, by using both human genital epithelial cell lines and primary genital epithelial cells as models, we found that HSV-2 infection enhances TLR9 expression at both mRNA and protein levels. Such enhancement is virus replication-dependent and CpG-independent, while the HSV-2-mediated upregulation of TLR9 does not activate TLR9 signaling pathway. Mechanistically, a SP1 binding site on TLR9 promoter appears to be essential for HSV-2-induced TLR9 transactivation. Upon HSV-2 infection, SP1 translocates from the cytoplasm to the nucleus, and consequently binds to TLR9 promoter. By using specific inhibitors, the JNK signaling pathway is shown to be involved in the HSV-2-induced TLR9 transactivation, while HSV-2 infection increases the phosphorylation but not the total level of JNK. In agreement, antagonism of JNK signaling pathway inhibits the HSV-2-induced SP1 nuclear translocation. Taken together, our study demonstrates that HSV-2 infection of human genital epithelial cells promotes TLR9 expression through SP1/JNK signaling pathway. Findings in this study provide insights into HSV-2-host interactions and potential targets for immune intervention
Solutions of the Strominger System via Stable Bundles on Calabi-Yau Threefolds
We prove that a given Calabi-Yau threefold with a stable holomorphic vector
bundle can be perturbed to a solution of the Strominger system provided that
the second Chern class of the vector bundle is equal to the second Chern class
of the tangent bundle. If the Calabi-Yau threefold has strict SU(3) holonomy
then the equations of motion derived from the heterotic string effective action
are also satisfied by the solutions we obtain.Comment: 19 pages, late
An improvement of isochronous mass spectrometry: Velocity measurements using two time-of-flight detectors
Isochronous mass spectrometry (IMS) in storage rings is a powerful tool for
mass measurements of exotic nuclei with very short half-lives down to several
tens of microseconds, using a multicomponent secondary beam separated in-flight
without cooling. However, the inevitable momentum spread of secondary ions
limits the precision of nuclear masses determined by using IMS. Therefore, the
momentum measurement in addition to the revolution period of stored ions is
crucial to reduce the influence of the momentum spread on the standard
deviation of the revolution period, which would lead to a much improved mass
resolving power of IMS. One of the proposals to upgrade IMS is that the
velocity of secondary ions could be directly measured by using two
time-of-flight (double TOF) detectors installed in a straight section of a
storage ring. In this paper, we outline the principle of IMS with double TOF
detectors and the method to correct the momentum spread of stored ions.Comment: Accepted by Nuclear Inst. and Methods in Physics Research,
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